2D Structure
loading...
2D chemical structural formula diagram.
3D Structure
loading...
This 3D model represents a theoretically simulated conformation and is for reference only.
Check the
Volasertib (BI6727)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | N-[4-[4-(cyclopropylmethyl)piperazin-1-yl]cyclohexyl]-4-[[(7R)-7-ethyl-5-methyl-6-oxo-8-propan-2-yl-7H-pteridin-2-yl]amino]-3-methoxybenzamide | |
|---|---|---|
| CAS Number | 755038-65-4 | |
| Molecular Formula |
C34H50N8O3 |
|
| Molecular Weight (MW) | 618.81 | |
| SMILES | CCC1C(=O)N(C2=CN=C(N=C2N1C(C)C)NC3=C(C=C(C=C3)C(=O)NC4CCC(CC4)N5CCN(CC5)CC6CC6)OC)C | |
| InChIKey | SXNJFOWDRLKDSF-XKHVUIRMSA-N |
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
35 mg/mL
(56.56 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
30 mg/mL
(48.48 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
30 mg/mL
(48.48 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
20 mg/mL
(32.32 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
20 mg/mL
(32.32 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
- Volasertib (BI6727) Mechanism of Action: PLK1 Inhibition in Leukemia Cell Research
- Volasertib (BI6727) Clinical Trials
- Volasertib (BI6727) Working Concentration | Cell Culture | Treatment
- Volasertib (BI6727) Solubility in DMSO
- Volasertib (BI6727) Stock Solution
- Volasertib (BI6727) Storage
- Volasertib (BI6727) Stability
- Volasertib (BI6727) Combination Database
- Volasertib (BI6727) Molecular Weight
- Volasertib (BI6727) SMILES
- Volasertib (BI6727) CAS Number
- Volasertib (BI6727) IC50 for Cell-based and Cell-free Assays
- Volasertib (BI6727) Sigma (SML3641)? Try a better option.
- Volasertib (BI6727) APExBIO (A8558)? Try a better option.
- Volasertib (BI6727) Cayman (18193)? Try a better option.
- Volasertib (BI6727) MedChemExpress (HY-12137)? Try a better option.
- Volasertib (BI6727) SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.