CAS No. 127-47-9

Batch: Purity:99.62
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Vitamin A Acetate Chemical Structure
Chemical Structure
Check the Vitamin A Acetate product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 127-47-9
Molecular Formula

C22H32O2
Molecular Weight (MW) 328.49
SMILES CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CCOC(=O)C)C)C

Ordering Information

Biological Activity

Vitamin A Acetate is an essential nutritional retinoid precursor that modulates retinoic acid receptor (RAR) signaling pathways. Upon cellular uptake and enzymatic conversion into active retinoic acid derivatives, it regulates nuclear receptor-mediated gene transcription. This pathway activation influences downstream cellular differentiation, cell cycle arrest, and apoptosis, thereby promoting epithelial tissue homeostasis and inhibiting aberrant cell proliferation.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 65 mg/mL (197.87 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 65 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.