CAS No. 125317-39-7

Batch: Purity:99.89
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Vinorelbine Ditartrate (KW-2307) Chemical Structure
Chemical Structure
Check the Vinorelbine Ditartrate (KW-2307) product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 125317-39-7
Molecular Formula

C45H54N4O8.2C4H6O6
Molecular Weight (MW) 1079.11
SMILES CCC1=CC2CC(C3=C(CN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)C78CCN9C7C(C=CC9)(C(C(C8N6C)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC.C(C(C(=O)O)O)(C(=O)O)O.C(C(C(=O)O)O)(C(=O)O)O

Ordering Information

Biological Activity

Vinorelbine Ditartrate is a semi-synthetic vinca alkaloid that acts as an inhibitor of microtubule dynamics through direct interaction with tubulin. By disrupting microtubule polymerization and mitotic spindle assembly, it inhibits proper chromosome segregation and induces cell cycle arrest at the M-phase. Downstream, this action suppresses cellular proliferation and triggers mitotic apoptosis, autophagy, and inflammatory pathways in tumor cells.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 100 mg/mL (92.66 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 100 mg/mL
Ethanol 100 mg/mL
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.