CAS No. 121-33-5
Batch:
Purity:99.99
Chemical Structure
Check the
Vanillin
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 121-33-5 | |
|---|---|---|
| Molecular Formula |
C8H8O3 |
|
| Molecular Weight (MW) | 152.15 |
Vanillin is a phenolic aldehyde that functions as an inhibitor of DNA-dependent protein kinase (DNA-PK). By targeting DNA-PK activity, vanillin impairs non-homologous end joining (NHEJ) repair of DNA double-strand breaks in mammalian cells. Consequently, this inhibition disrupts DNA repair pathways, leading to increased cellular sensitivity to ionizing radiation and DNA-damaging cytotoxic agents. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
30 mg/mL
(197.17 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 30 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
Note: Technical data last updated: Sep 1, 2026.