CAS No. 58-96-8
| IUPAC Name | 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione | |
|---|---|---|
| CAS Number | 58-96-8 | |
| Molecular Formula |
C9H12N2O6 |
|
| Molecular Weight (MW) | 244.2 | |
| SMILES | C1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)O | |
| InChIKey | DRTQHJPVMGBUCF-XVFCMESISA-N |
Uridine is an endogenous pyrimidine nucleoside that plays a critical role in RNA synthesis and pyrimidine nucleotide metabolism. It acts as an essential precursor for uridine triphosphate (UTP) and uridine diphosphate (UDP) formation via the pyrimidine salvage pathway, maintaining intracellular nucleotide homeostasis. Downstream, uridine supports membrane phospholipid biosynthesis and cellular energy metabolism through conversion into functional nucleotide derivatives. [1]
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Concentration
Volume
Mass
|
|---|
| Solvent | Solubility & Note |
|---|---|
| DMSO |
49 mg/mL
(200.65 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 49 mg/mL |
| Ethanol | Insoluble |
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
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