Cell-free Assays (IC50/Ki) for Ulixertinib (BVD-523)
| Key Target | IC50 (Cell-free) | Description | Reference |
|---|---|---|---|
| ERK1, ERK2 | ERK1: 15 nM, ERK2: 12 nM | Quantitative chemoproteomic assay (SILAC analyses, nonlinear regression analysis (one site –Fit log IC50) in GraphPad Prism) | Download PDF |
| hERG | 3.4 µM | Inhibition assay | Download PDF |
Cell-based Assay (IC50) for Ulixertinib (BVD-523)
| Cell Type | IC50 (Cell-based) | Description | Reference |
|---|---|---|---|
| MDA-GSCs and NHAs | 18-43 µM | AlamarBlue Cell Viability Assay, dose-response curves | Download PDF |
Check the
Ulixertinib (BVD-523)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
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- Ulixertinib (BVD-523) Mechanism of Action: ERK1/2 Inhibition in Melanoma Cell Research
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- Ulixertinib (BVD-523) Working Concentration | Cell Culture | Treatment
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- Ulixertinib (BVD-523) Combination Database
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- Ulixertinib (BVD-523) Sigma (AMBH2D6FB286)? Try a better option.
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