CAS No. 126784-99-4

Batch: Purity:99.95
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Ulipristal Acetate (CDB 2914) Chemical Structure
Chemical Structure
Check the Ulipristal Acetate (CDB 2914) product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 126784-99-4
Molecular Formula

C30H37NO4
Molecular Weight (MW) 475.62
SMILES CC(=O)C1(CCC2C1(CC(C3=C4CCC(=O)C=C4CCC23)C5=CC=C(C=C5)N(C)C)C)OC(=O)C

Biological Activity

Ulipristal acetate is a selective progesterone receptor modulator (SPRM) that targets the progesterone receptor (PR) with high affinity. By binding directly to PR, it competitively inhibits progesterone receptor activation and modulates downstream transcriptional activity within the PR signaling pathway. This receptor blockade suppresses progesterone-dependent gene expression, leading to the inhibition of follicular rupture and the suppression of ovulation in reproductive tissue. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 83 mg/mL (174.5 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 14 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
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Reference

[1] Attardi BJ, et al. Mol Cell Endocrinol. 2004;222(1-2):121-32.

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Note: Technical data last updated: Sep 1, 2026.