Target Selectivity of Trichostatin A (TSA)
| Key Target | IC50 | Description | Reference |
|---|---|---|---|
| HDAC1 | 0.0349 g/mL | HDAC1 inhibitory activity assay | PMC10384246 |
| HDAC4 | 3.349 g/mL | HDAC4 inhibitory activity assay | PMC10384246 |
Check the
Trichostatin A (TSA)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Cell-free Assays (IC50/Ki) for Trichostatin A (TSA)
| Key Target | IC50 (Cell-free) | Description | Reference |
|---|---|---|---|
| HDAC1 | 0.0349 g/mL | HDAC1 inhibitory activity assay | Download PDF |
| HDAC4 | 3.349 g/mL | HDAC4 inhibitory activity assay | Download PDF |
Cell-based Assay (IC50) for Trichostatin A (TSA)
| Cell Type | IC50 (Cell-based) | Description | Reference |
|---|---|---|---|
| T98G | 14.35 μM | Alamar Blue HS viability reagent assay | Download PDF |
| T98G (spheroids) | 45.39 μM | Alamar Blue HS viability reagent assay | Download PDF |
| meningioma WHO grade 1 spheroids | 1.25 µM | 3D Cell Viability Assay, IC50 values calculated using GraphPad Prism analysis software | Download PDF |
| meningioma WHO grade 2 spheroids | 1.60 µM | 3D Cell Viability Assay, IC50 values calculated using GraphPad Prism analysis software | Download PDF |
| MDA-MB-231 cells | 0.6 μM | CCK-8 assay | Download PDF |
| A549 | 30 µM | MTT assay | Download PDF |
| NCI-H1975 | 40 µM | MTT assay | Download PDF |
| Caco-2 | 2.5 µm | MTT assay | PMC8357004 |
Jump to
- Trichostatin A (TSA) Mechanism of Action: HDAC Inhibition in Cancer Cell Research
- Trichostatin A (TSA) Clinical Trials
- Trichostatin A (TSA) Working Concentration | Cell Culture | Treatment
- Trichostatin A (TSA) Solubility in DMSO
- Trichostatin A (TSA) Stock Solution
- Trichostatin A (TSA) Storage
- Trichostatin A (TSA) Stability
- Trichostatin A (TSA) Combination Database
- Trichostatin A (TSA) Molecular Weight
- Trichostatin A (TSA) SMILES
- Trichostatin A (TSA) CAS Number
- Trichostatin A (TSA) Chemical Structure (2D and 3D)
- Trichostatin A (TSA) IC50 for Cell-based and Cell-free Assays
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