CAS No. 61-54-1
Batch:
Purity:99.55
Chemical Structure
Check the
Tryptamine
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 2-(1H-indol-3-yl)ethanamine | |
|---|---|---|
| CAS Number | 61-54-1 | |
| Molecular Formula |
C10H12N2 |
|
| Molecular Weight (MW) | 160.22 | |
| SMILES | C1=CC=C2C(=C1)C(=CN2)CCN | |
| InChIKey | APJYDQYYACXCRM-UHFFFAOYSA-N |
Tryptamine is an endogenous monoamine alkaloid that functions as an agonist of human trace amine-associated receptor 1 (hTAAR1) and acts as a non-selective serotonin receptor agonist. By stimulating hTAAR1 and serotonin receptors, tryptamine modulates G-protein-coupled receptor signaling pathways, influencing neurotransmitter release and neuronal excitability. It also functions as a serotonin-norepinephrine-dopamine releasing agent, regulating monoaminergic signaling in the central nervous system. [1][2]
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
32 mg/mL
(199.72 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 32 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.