CAS No. 620-67-7

Batch: Purity:
Triheptanoin Chemical Structure
Chemical Structure
Check the Triheptanoin product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 620-67-7
Molecular Formula

C24H44O6
Molecular Weight (MW) 428.60
SMILES CCCCCCC(=O)OCC(COC(=O)CCCCCC)OC(=O)CCCCCC

Ordering Information

Biological Activity

Triheptanoin is a synthetic medium-chain triglyceride and anaplerotic substrate consisting of odd-chain heptanoate fatty acids. Upon metabolism, heptanoate enters the tricarboxylic acid (TCA) cycle via the propionyl-CoA carboxylase pathway to replenish critical TCA cycle intermediates. This anaplerotic mechanism preserves mitochondrial respiration, attenuates cellular oxidative stress, and protects against neuronal degeneration and energy depletion. [1][2]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.