CAS No. 322-79-2
| IUPAC Name | 2-acetyloxy-4-(trifluoromethyl)benzoic acid | |
|---|---|---|
| CAS Number | 322-79-2 | |
| Molecular Formula |
C10H7F3O4 |
|
| Molecular Weight (MW) | 248.16 | |
| SMILES | CC(=O)OC1=C(C=CC(=C1)C(F)(F)F)C(=O)O | |
| InChIKey | RMWVZGDJPAKBDE-UHFFFAOYSA-N |
Triflusal is an orally active antiplatelet agent that functions as a selective cyclooxygenase-1 (COX-1) inhibitor. It irreversibly inhibits COX-1 through acetylation of the enzyme, suppressing downstream production of thromboxane B2 in platelets. This inhibition disrupts arachidonic acid signaling pathways, leading to attenuated platelet activation and diminished vascular thrombotic potential without significantly interfering with vascular prostacyclin synthesis.
|
Concentration
Volume
Mass
|
|---|
| Solvent | Solubility & Note |
|---|---|
| DMSO |
50 mg/mL
(201.48 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 50 mg/mL |
| Water | Insoluble |
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.