CAS No. 117-89-5
Batch:
Purity:
Chemical Structure
Check the
Trifluoperazine
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 117-89-5 | |
|---|---|---|
| Molecular Formula |
C21H24F3N3S |
|
| Molecular Weight (MW) | 407.50 | |
| SMILES | CN1CCN(CC1)CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)C(F)(F)F |
Trifluoperazine is a small-molecule inhibitor of calmodulin and the dopamine D2 receptor. By binding to dopamine D2 receptors and inhibiting calcium-dependent calmodulin activation, it disrupts downstream G protein-coupled receptor signaling and calmodulin-mediated enzymatic pathways. These inhibitory actions impair intracellular calcium signaling and modulate dopaminergic neurotransmission, leading to altered central nervous system cellular phenotypes and signaling cascade regulation. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.