SMILES:

CCN1CCN(CC1)CC2=CC=C(NC(=O)C3=CC=C(C)C(=C3)OC4=C5C=C(OC)C(=CC5=NC=N4)OC)C=C2C(F)(F)F
TL02-59 Chemical Structure
Chemical Structure
Check the TL02-59 product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name 3-(6,7-dimethoxyquinazolin-4-yl)oxy-N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methylbenzamide
CAS Number 1315330-17-6
Molecular Formula

C32H34F3N5O4
Molecular Weight (MW) 609.64
SMILES CCN1CCN(CC1)CC2=CC=C(NC(=O)C3=CC=C(C)C(=C3)OC4=C5C=C(OC)C(=CC5=NC=N4)OC)C=C2C(F)(F)F
InChIKey AMHWQBGAKJESFB-UHFFFAOYSA-N

How to Prepare Stock Solution?

Concentration Volume Mass
🧮 Molarity Calculator

Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 100 mg/mL (164.03 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 1 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.