CAS No. 69558-55-0

Batch: Purity:99.87
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Thymopentin Chemical Structure
Chemical Structure
Check the Thymopentin product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 69558-55-0
Molecular Formula

C30H49N9O9
Molecular Weight (MW) 679.77
SMILES CC(C)C(C(=O)NC(CC1=CC=C(C=C1)O)C(=O)O)NC(=O)C(CC(=O)O)NC(=O)C(CCCCN)NC(=O)C(CCCN=C(N)N)N

Biological Activity

Thymopentin (TP5) is a synthetic pentapeptide immunomodulating agent corresponding to the active site of thymopoietin. It regulates T cell function by inducing intracellular cyclic GMP elevations in peripheral T lymphocytes, while selectively stimulating cyclic AMP accumulation in precursor T cells to trigger T cell differentiation. Through these cyclic nucleotide signaling pathways, thymopentin modulates immune responses and enhances T-lymphocyte maturation and immune activity. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 100 mg/mL (147.1 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 100 mg/mL
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Reference

[1] Goldstein G, et al. Science. 1979;204(4399):1309-10.

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Note: Technical data last updated: Sep 1, 2026.