CAS No. 59-43-8
Batch:
Purity:99.96
Chemical Structure
Check the
Thiamine monochloride
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 59-43-8 | |
|---|---|---|
| Molecular Formula |
C12H17ClN4OS |
|
| Molecular Weight (MW) | 300.81 | |
| SMILES | [Cl-].CC1=NC=C(C[N+]2=CSC(=C2C)CCO)C(=N1)N |
Thiamine monochloride is an essential water-soluble vitamin and precursor to thiamine pyrophosphate, a key cofactor for central metabolic enzymes including pyruvate dehydrogenase and transketolase. It regulates the tricarboxylic acid cycle and pentose phosphate pathway to support cellular energy production and ATP synthesis. Through these metabolic pathways, thiamine maintains oxidative glucose metabolism and supports normal neuronal function and cellular homeostasis. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
60 mg/mL
(199.46 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 60 mg/mL |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- Thiamine monochloride Clinical Trials
- Thiamine monochloride Solubility in DMSO
- Thiamine monochloride Stock Solution
- Thiamine monochloride Storage
- Thiamine monochloride Stability
- Thiamine monochloride Molecular Weight
- Thiamine monochloride SMILES
- Thiamine monochloride Chemical Structure (2D and 3D)
- Thiamine monochloride SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.