SMILES:

CC1=CC=CC(=C1)C2=CC(=CC=N2)NC3=CC=NC4=C3C=CC(=C4)C5=CC=C(C=C5)[S;v6](C)(=O)=O
TGFβRI-IN-3 Chemical Structure
Chemical Structure
Check the TGFβRI-IN-3 product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name N-[2-(3-methylphenyl)-4-pyridinyl]-7-(4-methylsulfonylphenyl)quinolin-4-amine
CAS Number 2763602-67-9
Molecular Formula

C28H23N3O2S
Molecular Weight (MW) 465.57
SMILES CC1=CC=CC(=C1)C2=CC(=CC=N2)NC3=CC=NC4=C3C=CC(=C4)C5=CC=C(C=C5)[S;v6](C)(=O)=O
InChIKey VYDDFPZEAIUBBH-UHFFFAOYSA-N

How to Prepare Stock Solution?

Concentration Volume Mass
🧮 Molarity Calculator

Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 93 mg/mL (199.75 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water Insoluble
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Jump to

Note: Technical data last updated: Sep 1, 2026.