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For research use only. Not for use in humans.

Tezepelumab (Anti-TSLP)

Synonyms: TSLP,Thymic stromal lymphopoietin

Tezepelumab (Anti-TSLP) is a potent human IgG2 monoclonal antibody that inhibits the binding of TSLP to the TSLP receptor, and also has potent efficacy and mechanism in asthma.

Tezepelumab (Anti-TSLP)

Quality Control

Batch: A230701 Purity: 99% Protein concentration: 6.59mg/ml Endotoxin Level: ＜1EU/mg
99

Mechanism of Action

Description
Tezepelumab (Anti-TSLP) is a potent human IgG2 monoclonal antibody that inhibits the binding of TSLP to the TSLP receptor, and also has potent efficacy and mechanism in asthma.

Product Details

CAS No. 1572943-04-4
Molecular Weight 145.5 kDa
Isotype Human IgG2
Source CHO
Purification AKTA
Sterility 0.2 μM filtered
Formulation 100 mM Pro-Ac, 20mM Arg, pH5.0
Storage
(From the date of receipt)		 Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT07013123 NOT_YET_RECRUITING Drug: Tezepelumab|Drug: Acarizax|Drug: Placebo Severe Asthma; Allergy to House Dust Mites University Hospital, Montpellier 2025-07-15 PHASE3
NCT07735494 RECRUITING Drug: Tezepelumab Severe Asthma University of Leeds 2026-07-31
NCT06878261 RECRUITING Chronic Obstructive Pulmonary Disease (COPD) AstraZeneca 2025-03-25 PHASE3
NCT06883305 RECRUITING Chronic Obstructive Pulmonary Disease (COPD) AstraZeneca 2025-03-18 PHASE3
NCT07771855 RECRUITING Drug: Tezepelumab Bronchiolitis Obliterans Syndrome (BOS); HSCT; Bronchial Disease Hopital Foch 2026-06-24 PHASE2
NCT07302516 NOT_YET_RECRUITING Asthma Qilu Pharmaceutical Co., Ltd. 2025-12-25 PHASE3

(data from https://clinicaltrials.gov, updated on 2025-06-10)

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