Home Biosimilar Antibodies Immunology & Inflammation CD markers Teclistamab (Anti-BCMA & CD3)
For research use only. Not for use in humans.

Teclistamab (Anti-BCMA & CD3)

Synonyms: JNJ-64007957

Teclistamab is a humanized bispecific IgG4 monoclonal antibody that targets CD3 on T cells and B-cell maturation antigen (BCMA) on multiple myeloma (MM) cells. It triggers a T cell-mediated immune response, leading to the elimination of BCMA-positive cells and exhibits the potential to treat patients with triple-class exposed relapsed/refractory multiple myeloma (R/RMM). MW: 143.66 KD.

Teclistamab (Anti-BCMA & CD3)

Quality Control

Batch: A402901 Purity: 99% Protein concentration: 5.327mg/ml Endotoxin Level: ＜1EU/mg
99

Specificity

Name Citation CD38 CD45 CD39 CD88 CD73 Others
RBN013209 0
MK-0159 0
CD38 inhibitor 1 (compound 78c) 7
AB680 0
NQ301 1 TXA2 receptor
SodiuM Metatungstate 3
PMX-53 3
LY-3475070 2
Expand to Check More
1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Mechanism of Action

Description
Teclistamab is a humanized bispecific IgG4 monoclonal antibody that targets CD3 on T cells and B-cell maturation antigen (BCMA) on multiple myeloma (MM) cells. It triggers a T cell-mediated immune response, leading to the elimination of BCMA-positive cells and exhibits the potential to treat patients with triple-class exposed relapsed/refractory multiple myeloma (R/RMM). MW: 143.66 KD.

Product Details

CAS No. 2119595-80-9
Source CHO
Storage
(From the date of receipt)		 -80℃(avoid freeze-thaw cycles)

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

Tech Support

Handling Instructions

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