CAS No. 161715-24-8

Batch: Purity:99.65
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Tebipenem Pivoxil (L084) Chemical Structure
Chemical Structure
Check the Tebipenem Pivoxil (L084) product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name 2,2-dimethylpropanoyloxymethyl (4R,5S,6S)-3-[1-(4,5-dihydro-1,3-thiazol-2-yl)azetidin-3-yl]sulfanyl-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate
CAS Number 161715-24-8
Molecular Formula

C22H31N3O6S2
Molecular Weight (MW) 497.63
SMILES CC1C2C(C(=O)N2C(=C1SC3CN(C3)C4=NCCS4)C(=O)OCOC(=O)C(C)(C)C)C(C)O
InChIKey SNUDIPVBUUXCDG-QHSBEEBCSA-N

Ordering Information

Biological Activity

Tebipenem pivoxil (L-084) is an oral prodrug of tebipenem, belonging to the carbapenem class of antibiotics. It targets penicillin-binding proteins to inhibit peptidoglycan cross-linking during bacterial cell wall synthesis. Blockade of cell wall assembly disrupts cell wall integrity, leading to osmotic lysis and cell death. Consequently, tebipenem pivoxil exhibits potent bactericidal activity against common respiratory and otolaryngologic bacterial pathogens.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 99 mg/mL (198.94 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 87 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.