EPZ-6438 (Tazemetostat) is a potent and highly selective EZH2 inhibitor. It works by binding to the EZH2 enzyme, blocking H3K27 methylation and PRC2-mediated epigenetic silencing. This reactivates tumor suppressors, showing high therapeutic value in lymphomas and sarcomas.
EPZ-6438 (Tazemetostat) IC50 for Cell-based and Cell-free Assays
Comprehensive lC50 Values for EPZ-6438 (Tazemetostat) Across Cell-free Enzyme Inhibitory Profiles and Cell- based Functional Assays.