CAS No. 516-35-8

Batch: Purity:100.00
Taurochenodeoxycholic acid Chemical Structure
Chemical Structure
Check the Taurochenodeoxycholic acid product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 516-35-8
Molecular Formula

C26H45NO6S

Molecular Weight (MW) 499.70
SMILES CC(CCC(=O)NCCS(=O)(=O)O)C1CCC2C1(CCC3C2C(CC4C3(CCC(C4)O)C)O)C

Ordering Information

Biological Activity

Taurochenodeoxycholic acid is an endogenous bioactive conjugated bile acid that functions as a natural agonist for the farnesoid X receptor (FXR). Activation of FXR by taurochenodeoxycholic acid regulates bile acid synthesis, transport, and metabolic homeostasis through downstream gene expression pathways. It is widely utilized as a cholagogue and choleretic agent to promote bile secretion and hepatobiliary transport. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 100 mg/mL (200.12 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 100 mg/mL
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.