Molecular Weight: 454.53 g/mol
Chemical Structure
Check the
TAS-116 (Pimitespib)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
91 mg/mL
(200.2 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 11 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer longer shelf life compared to stock solutions.
Looking for a specific aliquot size? Contact your local sales representative or orders@selleckchem.com.
Chemical Information
| IUPAC Name | 3-ethyl-4-[4-[4-(1-methylpyrazol-4-yl)imidazol-1-yl]-3-propan-2-ylpyrazolo[3,4-b]pyridin-1-yl]benzamide | |
|---|---|---|
| CAS Number | 1260533-36-5 | |
| Molecular Formula |
C25H26N8O |
|
| Molecular Weight (MW) | 454.53 | |
| SMILES | CCC1=C(C=CC(=C1)C(=O)N)N2C3=NC=CC(=C3C(=N2)C(C)C)N4C=C(N=C4)C5=CN(N=C5)C | |
| InChIKey | NVVPMZUGELHVMH-UHFFFAOYSA-N |
Jump to
- TAS-116 (Pimitespib) Mechanism of Action: HSP90 Inhibition in Tumor Cell Research
- TAS-116 (Pimitespib) Clinical Trials
- TAS-116 (Pimitespib) Working Concentration | Cell Culture | Treatment
- TAS-116 (Pimitespib) Solubility in DMSO
- TAS-116 (Pimitespib) Stock Solution
- TAS-116 (Pimitespib) Storage
- TAS-116 (Pimitespib) Stability
- TAS-116 (Pimitespib) Combination Database
- TAS-116 (Pimitespib) SMILES
- TAS-116 (Pimitespib) CAS Number
- TAS-116 (Pimitespib) Chemical Structure (2D and 3D)
- TAS-116 (Pimitespib) IC50 for Cell-based and Cell-free Assays
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- TAS-116 (Pimitespib) Sigma (BL3H9A3B23A5)? Try a better option.
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- TAS-116 (Pimitespib) SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.