Molecular Weight: 822.04 g/mol
Chemical Structure
Check the
Tacrolimus monohydrate
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(121.64 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 100 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
| IUPAC Name | (1R,9S,12S,13R,14S,17R,18E,21S,23S,24R,25S,27R)-1,14-dihydroxy-12-[(E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-23,25-dimethoxy-13,19,21,27-tetramethyl-17-prop-2-enyl-11,28-dioxa-4-azatricyclo[22.3.1.04,9]octacos-18-ene-2,3,10,16-tetrone;hydrate | |
|---|---|---|
| CAS Number | 109581-93-3 | |
| Molecular Formula |
C44H69NO12.H2O |
|
| Molecular Weight (MW) | 822.04 | |
| InChIKey | NWJQLQGQZSIBAF-MLAUYUEBSA-N |
- Tacrolimus monohydrate Clinical Trials
- Tacrolimus monohydrate Solubility in DMSO
- Tacrolimus monohydrate Stock Solution
- Tacrolimus monohydrate Storage
- Tacrolimus monohydrate Stability
- Tacrolimus monohydrate CAS Number
- Tacrolimus monohydrate Chemical Structure (2D and 3D)
- Tacrolimus monohydrate SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.