CAS No. 17388-39-5
Batch:
Purity:99.76
Chemical Structure
Check the
Swertiamarin
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 17388-39-5 | |
|---|---|---|
| Molecular Formula |
C16H22O10 |
|
| Molecular Weight (MW) | 374.34 | |
| SMILES | C=CC1C(OC=C2C1(CCOC2=O)O)OC3C(C(C(C(O3)CO)O)O)O |
Swertiamarin is a natural secoiridoid glucoside with anti-inflammatory, anticancer, hypoglycemic, and hypolipidemic activities. It inhibits pro-inflammatory signaling through modulation of the NF-κB pathway, suppressing downstream expression of cytokines such as TNF-α, IL-1β, and IL-6. Additionally, swertiamarin regulates lipid metabolism and glucose homeostasis, demonstrating protective cellular effects against oxidative stress and inflammatory damage in experimental models. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
74 mg/mL
(197.68 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.