Clinical Trials

Sunitinib has been extensively evaluated across numerous clinical trials spanning Phase 1 to Phase 3, focusing primarily on solid tumors such as renal cell carcinoma, gastrointestinal stromal tumors, non-small cell lung cancer, prostate neoplasms, and breast cancer. Sponsored by pharmaceutical entities and academic institutions, these investigations encompass actively recruiting, completed, terminated, and withdrawn protocols. Recent research evaluates sunitinib in combination regimens for renal cell carcinoma and MET-driven papillary renal cell carcinoma.

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT06032728 NOT_YET_RECRUITING
Renal Cell Carcinoma
First Affiliated Hospital, Sun Yat-Sen University
2023-10-01
NCT06726421 RECRUITING
Renal Cell Carcinoma (Kidney Cancer); Kidney Cancer Metastatic; Renal Cell Carcinoma Metastatic
Sun Yat-sen University
2024-09-18 PHASE3
NCT03899155 RECRUITING
Cancer
Bristol-Myers Squibb
2019-08-09 PHASE2
NCT03768063 ACTIVE_NOT_RECRUITING
Cancer
Hoffmann-La Roche
2019-02-28 PHASE3
NCT07218926 RECRUITING
Gastrointestinal Neoplasms
GlaxoSmithKline
2025-12-03 PHASE3
NCT07477457 RECRUITING
Osteosarcoma; Metastasis
Memorial Sloan Kettering Cancer Center
2026-03-11 PHASE2
NCT02693535 RECRUITING
Lymphoma, Non-Hodgkin; Multiple Myeloma; Advanced Solid Tumors
American Society of Clinical Oncology
2016-03-14 PHASE2
NCT00329043 ACTIVE_NOT_RECRUITING
Prostate Cancer
M.D. Anderson Cancer Center
2006-05-15 PHASE2
NCT07096609 RECRUITING
GIST
Asan Medical Center
2025-10-29 PHASE1; PHASE2
NCT07667751 RECRUITING
Ovary Cancer
Bai-Rong Xia
2026-06-01 PHASE2
NCT07689201 NOT_YET_RECRUITING
Gastrointestinal Neoplasms
GlaxoSmithKline
2026-08-31 PHASE2
NCT05734105 ACTIVE_NOT_RECRUITING
GIST
Deciphera Pharmaceuticals, LLC
2023-12-13 PHASE3
NCT02925234 RECRUITING
Cancer; Tumors; Neoplasm; Neoplasia
The Netherlands Cancer Institute
2016-08 PHASE2
NCT05905887 RECRUITING
Gastrointestinal Stromal Tumors
Asan Medical Center
2023-09-06 PHASE2
NCT03900793 RECRUITING
Osteosarcoma
University of Colorado, Denver
2019-08-26 PHASE1
NCT03541902 ACTIVE_NOT_RECRUITING
Malignant Neoplasms of Urinary Tract; Renal Cell Carcinoma; Chromophobe Renal Cell Carcinoma; Metastatic Renal Cell Carcinoma; Papillary Renal Cell Carcinoma; Renal Cell Carcinoma Associated With Xp11.2 Translocations/TFE3 Gene Fusions; Sarcomatoid Renal Cell Carcinoma; Stage IV Renal Cell Cancer AJCC v8; Unclassified Renal Cell Carcinoma
M.D. Anderson Cancer Center
2018-05-15 PHASE2
NCT06326346 RECRUITING
Gastrointestinal Stromal Tumors
Asan Medical Center
2024-11-20 PHASE2
NCT05366816 RECRUITING
Gastrointestinal Stromal Tumors
University of Miami
2023-10-17 PHASE2
NCT02068586 ACTIVE_NOT_RECRUITING
Ciliary Body and Choroid Melanoma, Medium/Large Size; Ciliary Body and Choroid Melanoma, Small Size; Iris Melanoma; Stage I Intraocular Melanoma; Stage IIA Intraocular Melanoma; Stage IIB Intraocular Melanoma; Stage IIIA Intraocular Melanoma; Stage IIIB Intraocular Melanoma; Stage IIIC Intraocular Melanoma; Stage I Uveal Melanoma AJCC V7; Stage II Uveal Melanoma AJCC V7; Stage III Uveal Melanoma AJCC V7
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
2014-11-19 PHASE2
NCT02465060 ACTIVE_NOT_RECRUITING
Advanced Lymphoma; Advanced Malignant Solid Neoplasm; Bladder Carcinoma; Breast Carcinoma; Cervical Carcinoma; Colon Carcinoma; Colorectal Carcinoma; Endometrial Carcinoma; Esophageal Carcinoma; Exocrine Pancreas Carcinoma; Gastric Carcinoma; Glioma; Head and Neck Carcinoma; Hematopoietic and Lymphoid Cell Neoplasm; Kidney Carcinoma; Liver Carcinoma; Lung Carcinoma; Lymphoma; Malignant Uterine Corpus Neoplasm; Malignant Uterine Neoplasm; Melanoma; Multiple Myeloma; Ovarian Carcinoma; Prostate Carcinoma; Rectal Carcinoma; Recurrent Bladder Carcinoma; Recurrent Breast Carcinoma; Recurrent Cervical Carcinoma; Recurrent Colon Carcinoma; Recurrent Colorectal Carcinoma; Recurrent Esophageal Carcinoma; Recurrent Gastric Carcinoma; Recurrent Glioma; Recurrent Head and Neck Carcinoma; Recurrent Liver Carcinoma; Recurrent Lung Carcinoma; Recurrent Lymphoma; Recurrent Malignant Solid Neoplasm; Recurrent Malignant Uterine Corpus Neoplasm; Recurrent Melanoma; Recurrent Multiple Myeloma; Recurrent Ovarian Carcinoma; Recurrent Pancreatic Carcinoma; Recurrent Prostate Carcinoma; Recurrent Rectal Carcinoma; Recurrent Skin Carcinoma; Recurrent Thyroid Gland Carcinoma; Refractory Lymphoma; Refractory Malignant Solid Neoplasm; Refractory Multiple Myeloma; Skin Carcinoma; Thyroid Gland Carcinoma
National Cancer Institute (NCI)
2015-08-17 PHASE2
NCT03297606 RECRUITING
Lymphoma, Non-Hodgkin; Multiple Myeloma; Advanced Solid Tumors
Canadian Cancer Trials Group
2018-03-23 PHASE2
NCT05678673 ACTIVE_NOT_RECRUITING
Non-Clear Cell Renal Cell Carcinoma
Exelixis
2023-01-01 PHASE3
NCT05687123 RECRUITING
Metastatic Pancreatic Neuroendocrine Tumor; Pancreatic Neoplasm; Stage III Pancreatic Neuroendocrine Tumor AJCC v8; Stage IV Pancreatic Neuroendocrine Tumor AJCC v8; Unresectable Pancreatic Neuroendocrine Tumor
National Cancer Institute (NCI)
2024-08-14 PHASE1
NCT00715442 ACTIVE_NOT_RECRUITING
Renal Cell Carcinoma
M.D. Anderson Cancer Center
2008-06-24 PHASE2
NCT05024214 RECRUITING
Solid Tumors; Non-small Cell Lung Cancer; Renal Cell Carcinoma; Hepatocellular Carcinoma
3D Medicines (Sichuan) Co., Ltd.
2021-11-15 PHASE1; PHASE2
NCT05477576 RECRUITING
GEP-NET; Gastroenteropancreatic Neuroendocrine Tumor; Gastroenteropancreatic Neuroendocrine Tumor Disease; Neuroendocrine Tumors; Carcinoid; Carcinoid Tumor; Pancreatic NET
RayzeBio, Inc.
2022-03-24 PHASE3
NCT05245968 ACTIVE_NOT_RECRUITING
Gastrointestinal Stromal Tumors
Taiho Pharmaceutical Co., Ltd.
2021-12-01 PHASE1
NCT03463460 ACTIVE_NOT_RECRUITING
Thymic Carcinoma
Dwight Owen
2018-06-19 PHASE2
NCT06222593 RECRUITING
Carcinoma, Renal Cell
State University of New York at Buffalo
2024-10-01 PHASE1; PHASE2
NCT02688491 UNKNOWN
Renal Neoplasms; Targeted Molecular Therapy
First Affiliated Hospital, Sun Yat-Sen University
2016-07
NCT06208748 ACTIVE_NOT_RECRUITING
Gastrointestinal Stromal Tumors; GIST
Sarcoma Alliance for Research through Collaboration
2024-08-01 PHASE2
NCT05751733 RECRUITING
Gastrointestinal Stromal Tumors
Xiangya Hospital of Central South University
2023-02-01
NCT06940349 RECRUITING
Solid Tumors Refractory to Standard Therapy
Rabin Medical Center
2021-10-21 PHASE1; PHASE2
NCT05043090 ACTIVE_NOT_RECRUITING
Papillary Renal Cell Carcinoma
AstraZeneca
2021-10-28 PHASE3
NCT05208047 RECRUITING
Advanced Gastrointestinal Stromal Tumors; Metastatic Cancer
Cogent Biosciences, Inc.
2022-04-14 PHASE3
NCT04523272 ACTIVE_NOT_RECRUITING
Advanced Renal Cancer
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2020-08-25 PHASE3
NCT05949424 UNKNOWN
Renal Cell Carcinoma; Ovarian Carcinoma; Thyroid Carcinoma; Breast Carcinoma; Endometrium Carcinoma
University Medical Center Groningen
2024-05 PHASE4
NCT03944304 COMPLETED
Gastrointestinal Stromal Tumors
Asan Medical Center
2019-05-27 PHASE2
NCT04893785 RECRUITING
Lung Neuroendocrine Neoplasm; GEP Neuroendocrine Tumor
National Cancer Institute, Naples
2021-06-15 PHASE2
NCT03277924 COMPLETED
Soft Tissue Sarcoma; Bone Sarcoma
Grupo Espanol de Investigacion en Sarcomas
2017-05-31 PHASE1; PHASE2
NCT06222593 Not yet recruiting
Carcinoma Renal Cell
State University of New York at Buffalo
2024-06-01 Phase 1|Phase 2
NCT04394975 COMPLETED
Primary Disease: Unresectable or Metastatic Renal Cell Carcinoma Focus of the Study:PFS Assessed by IRC Per RECIST 1.1
Shanghai Junshi Bioscience Co., Ltd.
2020-08-20 PHASE3
NCT02230176 COMPLETED
Pancreatic Neuroendocrine Carcinoma
Gustave Roussy, Cancer Campus, Grand Paris
2015-02 PHASE2
NCT06208748 Not yet recruiting
Gastrointestinal Stromal Tumors|GIST
Sarcoma Alliance for Research through Collaboration|Cogent Biosciences Inc.|Dana-Farber Cancer Institute|The Life Raft Group
2024-03 Phase 2
NCT02689167 UNKNOWN
Kidney Neoplasms; Metastatic Renal Cell Cancer
Centre Hospitalier Universitaire de Besancon
2016-02-19 PHASE2
NCT04193553 COMPLETED
Gastro Intestinal Stromal Tumour
Centre Leon Berard
2020-01-17 PHASE2
NCT03013946 TERMINATED
Renal Cell Carcinoma, Metastatic; Renal Cell Cancer, Recurrent
AIO-Studien-gGmbH
2017-01-18 PHASE3
NCT05816642 UNKNOWN
Metastatic Renal Cell Carcinoma
RenJi Hospital
2022-08-01
NCT01254864 COMPLETED
Prostate Cancer
M.D. Anderson Cancer Center
2011-03-16 PHASE2
NCT01391962 COMPLETED
Sarcoma, Alveolar Soft Part
National Cancer Institute (NCI)
2011-07-18 PHASE2
NCT02761057 COMPLETED
Locally Advanced Papillary Renal Cell Carcinoma; Metastatic Papillary Renal Cell Carcinoma; Stage III Renal Cell Cancer AJCC v7; Stage IV Renal Cell Cancer AJCC v7; Type 1 Papillary Renal Cell Carcinoma; Type 2 Papillary Renal Cell Carcinoma; Unresectable Renal Cell Carcinoma
National Cancer Institute (NCI)
2016-07-25 PHASE2
NCT02684006 COMPLETED
Renal Cell Cancer
Pfizer
2016-03-23 PHASE3
NCT00813423 COMPLETED
Adult Solid Neoplasm
National Cancer Institute (NCI)
2010-02-19 PHASE1
NCT06390826 ACTIVE_NOT_RECRUITING
Advanced Lymphoma; Advanced Malignant Solid Neoplasm; Refractory Lymphoma; Refractory Malignant Solid Neoplasm; Refractory Multiple Myeloma
National Cancer Institute (NCI)
2016-11-01 PHASE2
NCT05745142 Completed
Carcinoma Renal Cell|Clear-cell Metastatic Renal Cell Carcinoma
Pfizer
2023-02-23 --
NCT03571438 UNKNOWN
Kidney Cancer
University Hospital, Grenoble
2017-10-16
NCT04006769 COMPLETED
Gastrointestinal Stromal Tumor, Malignant
Xiangya Hospital of Central South University
2020-10-30 EARLY_PHASE1
NCT04633122 COMPLETED
Gastrointestinal Stromal Tumor(GIST)
Zai Lab (Shanghai) Co., Ltd.
2020-11-25 PHASE2
NCT03449173 UNKNOWN
Type B3 Thymoma; Thymic Carcinoma
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
2017-03-02 PHASE2
NCT04409223 TERMINATED
Gastrointestinal Stromal Tumors
Jiangsu HengRui Medicine Co., Ltd.
2020-09-12 PHASE3
NCT00843037 COMPLETED
Paraganglioma; Pheochromocytoma
University Health Network, Toronto
2009-02 PHASE2
NCT03905889 TERMINATED
Renal Cell Carcinoma Metastatic
Brown University
2019-06-05 PHASE1
NCT03729245 TERMINATED
Renal Cell Carcinoma; Metastatic Renal Cell Carcinoma
Nektar Therapeutics
2018-12-18 PHASE3
NCT03025893 UNKNOWN
Glioblastoma Multiforme; Glioblastoma, Adult; Glioblastoma; Recurrent Brain Tumor; GBM
Amsterdam UMC, location VUmc
2018-08-31 PHASE2; PHASE3
NCT03609424 COMPLETED
Gastrointestinal Stromal Tumors
Asan Medical Center
2019-02-14 PHASE1; PHASE2
NCT02239952 UNKNOWN
Cancer; High-grade Glioma
Amsterdam UMC, location VUmc
2014-11
NCT03170180 COMPLETED
Stomach Neoplasms
Samsung Medical Center
2017-03-01 PHASE2
NCT05043090 Recruiting
Papillary Renal Cell Carcinoma
AstraZeneca
2021-10-28 Phase 3
NCT03673501 ACTIVE_NOT_RECRUITING
Gastrointestinal Stromal Tumors
Deciphera Pharmaceuticals, LLC
2019-02-08 PHASE3
NCT03909724 UNKNOWN
Colorectal Cancer; Metastasis
Amsterdam UMC, location VUmc
2019-10-01 PHASE2; PHASE3
NCT03862768 UNKNOWN
Gastrointestinal Stromal Tumors; Surgery
Shanghai Zhongshan Hospital
2019-07
NCT01621568 COMPLETED
Thymoma; Thymus Neoplasms
National Cancer Institute (NCI)
2012-05-15 PHASE2
NCT03641326 TERMINATED
Gliosarcoma; Central Nervous System Sarcoma
National Cancer Institute (NCI)
2019-02-21 PHASE2
NCT02019576 COMPLETED
Clear Cell Metastatic Renal Cell Carcinoma
Sunnybrook Health Sciences Centre
2014-05 PHASE2
NCT02960906 COMPLETED
Clear Cell Metastatic Renal Cell Carcinoma
Association Pour La Recherche des Thérapeutiques Innovantes en Cancérologie
2017-05-31 PHASE2
NCT02432846 COMPLETED
Renal Cell Carcinoma, Metastatic
Mendus
2015-04 PHASE2
NCT04669366 Completed
Kidney Neoplasms
Pfizer
2021-01-20 --
NCT03953079 COMPLETED
Neovascular Age-Related Macular Degeneration
Graybug Vision
2019-09-26 PHASE2
NCT03878524 TERMINATED
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Anatomic Stage IV Breast Cancer AJCC v8; Anemia; Ann Arbor Stage III Hodgkin Lymphoma; Ann Arbor Stage III Non-Hodgkin Lymphoma; Ann Arbor Stage IV Hodgkin Lymphoma; Ann Arbor Stage IV Non-Hodgkin Lymphoma; Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative; Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Castration-Resistant Prostate Carcinoma; Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Hematopoietic and Lymphoid System Neoplasm; Locally Advanced Pancreatic Adenocarcinoma; Metastatic Breast Carcinoma; Metastatic Malignant Solid Neoplasm; Metastatic Pancreatic Adenocarcinoma; Myelodysplastic/Myeloproliferative Neoplasm With Ring Sideroblasts and Thrombocytosis; Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable; Primary Myelofibrosis; Recurrent Acute Lymphoblastic Leukemia; Recurrent Acute Myeloid Leukemia; Recurrent Chronic Lymphocytic Leukemia; Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Recurrent Hematologic Malignancy; Recurrent Hodgkin Lymphoma; Recurrent Myelodysplastic Syndrome; Recurrent Myelodysplastic/Myeloproliferative Neoplasm; Recurrent Myeloproliferative Neoplasm; Recurrent Non-Hodgkin Lymphoma; Recurrent Plasma Cell Myeloma; Recurrent Small Lymphocytic Lymphoma; Refractory Acute Lymphoblastic Leukemia; Refractory Acute Myeloid Leukemia; Refractory Chronic Lymphocytic Leukemia; Refractory Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Refractory Chronic Myelomonocytic Leukemia; Refractory Hematologic Malignancy; Refractory Hodgkin Lymphoma; Refractory Malignant Solid Neoplasm; Refractory Myelodysplastic Syndrome; Refractory Myelodysplastic/Myeloproliferative Neoplasm; Refractory Non-Hodgkin Lymphoma; Refractory Plasma Cell Myeloma; Refractory Primary Myelofibrosis; Refractory Small Lymphocytic Lymphoma; Stage II Pancreatic Cancer AJCC v8; Stage III Pancreatic Cancer AJCC v8; Stage IV Pancreatic Cancer AJCC v8; Stage IV Prostate Cancer AJCC v8; Unresectable Pancreatic Adenocarcinoma
OHSU Knight Cancer Institute
2020-04-01 PHASE1
NCT01664182 COMPLETED
Advanced Renal Cell Carcinoma; Advanced Sarcomatoid Renal Cell Carcinoma; Stage III Renal Cell Cancer AJCC v7; Stage IV Renal Cell Cancer AJCC v7
National Cancer Institute (NCI)
2012-08-01 PHASE2
NCT01694277 COMPLETED
Gastrointestinal Stromal Tumors
AB Science
2012-04 PHASE3
NCT02919371 UNKNOWN
Renal Cell Carcinoma
King Faisal Specialist Hospital & Research Center
2014-12 PHASE1; PHASE2
NCT03066427 COMPLETED
Clear Cell Renal Carcinoma
Spanish Oncology Genito-Urinary Group
2017-05-10 PHASE2
NCT02811861 ACTIVE_NOT_RECRUITING
Renal Cell Carcinoma
Eisai Inc.
2016-10-13 PHASE3
NCT02959554 TERMINATED
Metastatic Renal Cell Carcinoma
AIO-Studien-gGmbH
2016-12 PHASE2
NCT04085341 COMPLETED
Diabetic Macular Edema; Retina Vein Occlusion
Graybug Vision
2019-09-11 PHASE2
NCT02401815 COMPLETED
Gastrointestinal Stromal Tumors
Cogent Biosciences, Inc.
2015-03-06 PHASE1; PHASE2
NCT02790580 UNKNOWN
Breast Cancer
National University Hospital, Singapore
2016-05 PHASE2
NCT00543504 COMPLETED
Advanced Cancer
M.D. Anderson Cancer Center
2007-10-10 PHASE1
NCT01566747 COMPLETED
Renal Cell Carcinoma
Cancer Trials Ireland
2011-03 PHASE2
NCT01164228 COMPLETED
Kidney Cancer
ECOG-ACRIN Cancer Research Group
2010-09-17 PHASE2
NCT02420821 COMPLETED
Renal Cell Carcinoma
Hoffmann-La Roche
2015-05-20 PHASE3
NCT03141177 COMPLETED
Renal Cell Carcinoma
Bristol-Myers Squibb
2017-07-23 PHASE3
NCT02555748 COMPLETED
Metastatic Renal Cell Cancer
Institut Claudius Regaud
2015-11-17 PHASE4
NCT02342600 WITHDRAWN
Gastrointestinal Stromal Tumors
Sarcoma Alliance for Research through Collaboration
2017-01 PHASE2
NCT03592199 UNKNOWN
Clear Cell Renal Cell Carcinoma
Instituto do Cancer do Estado de São Paulo
2017-12-11 PHASE2
NCT03323710 WITHDRAWN
Renal Cell Carcinoma
Military Institute od Medicine National Research Institute
2018-09 PHASE2
NCT02713763 COMPLETED
Pancreatic Neuroendocrine Tumour Metastatic
Grupo Espanol de Tumores Neuroendocrinos
2017-02-14 PHASE2
NCT03109015 COMPLETED
Carcinoma, Renal Cell
Duke University
2017-09-27 PHASE2
NCT01185366 TERMINATED
Kidney Cancer
M.D. Anderson Cancer Center
2010-08 PHASE2
NCT02450123 COMPLETED
Refractory Solid Tumors
Samsung Medical Center
2016-03-23
NCT02691793 COMPLETED
Refractory Solid Tumors
Samsung Medical Center
2017-11-20 PHASE4
NCT03091192 ACTIVE_NOT_RECRUITING
Carcinoma; Carcinoma, Renal Cell; Kidney Neoplasms; Urologic Neoplasms; Kidney Diseases; Neoplasms by Site; Enzyme Inhibitors; Protein Kinase Inhibitors
AstraZeneca
2017-07-25 PHASE3
NCT02058901 COMPLETED
Solid Tumors
Amsterdam UMC, location VUmc
2013-07 PHASE1
NCT02315625 TERMINATED
Neuroendocrine Tumors; Neuroendocrine Carcinoma; Neuroendocrine Neoplasms; Carcinoma, Neuroendocrine; Neuroendocrine Tumors of the Gastrointestinal Tract and Pancreas
National Cancer Institute (NCI)
2015-04-08 PHASE2
NCT02216578 COMPLETED
Metastatic Gastrointestinal Stromal Tumor
European Organisation for Research and Treatment of Cancer - EORTC
2017-02-02 PHASE2
NCT02483247 COMPLETED
Cancer
Sumitomo Pharma America, Inc.
2015-09 PHASE1
NCT01309633 COMPLETED
Nasopharyngeal Carcinoma
National University Hospital, Singapore
2011-09-02 PHASE2
NCT00478426 COMPLETED
Endometrial Adenocarcinoma; Endometrial Endometrioid Adenocarcinoma; Endometrial Serous Adenocarcinoma; Recurrent Uterine Corpus Carcinoma; Stage IVA Uterine Corpus Cancer AJCC v7; Stage IVB Uterine Corpus Cancer AJCC v7; Uterine Carcinosarcoma; Uterine Corpus Carcinosarcoma
National Cancer Institute (NCI)
2007-04-30 PHASE2
NCT05800106 COMPLETED
Gastrointestinal Stromal Tumors; Renal Cell Carcinoma; Pancreatic Neuroendocrine Tumor
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2018-12-04 PHASE1
NCT02060370 COMPLETED
Genitourinary Cancer; Kidney Cancer
M.D. Anderson Cancer Center
2014-08 PHASE2
NCT02570789 TERMINATED
Clear-cell Metastatic Renal Cell Carcinoma
Cliniques universitaires Saint-Luc- Université Catholique de Louvain
2012-12 PHASE4
NCT03035630 WITHDRAWN
Clear-cell Renal Cell Carcinoma; RCC; Kidney Cancer; Clear-cell Kidney Carcinoma
Guru Sonpavde
2017-05-23 PHASE2
NCT00930033 COMPLETED
Metastatic Renal Cell Carcinoma
Assistance Publique - Hôpitaux de Paris
2009-09-09 PHASE3
NCT01735968 COMPLETED
3rd Line GIST
Novartis Pharmaceuticals
2013-02-27 PHASE1
NCT02853331 COMPLETED
Renal Cell Carcinoma
Merck Sharp & Dohme LLC
2016-09-16 PHASE3
NCT02535351 TERMINATED
Clear-cell Metastatic Renal Cell Carcinoma
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
2015-11 PHASE3
NCT03249740 COMPLETED
Neovascular Age-Related Macular Degeneration
Graybug Vision
2017-08-29 PHASE1
NCT03260894 COMPLETED
Renal Cell Carcinoma (RCC)
Incyte Corporation
2017-12-07 PHASE3
NCT01517243 COMPLETED
Metastatic Renal Cell Carcinoma
Dartmouth-Hitchcock Medical Center
2010-09-22 PHASE2
NCT03275558 WITHDRAWN
Recurrent Glioblastoma; Gliosarcoma; Anaplastic Gliomas
Center Trials & Treatment
2018-07-17 PHASE1
NCT02402062 COMPLETED
Neuroendocrine Tumors; Pancreatic Neoplasms
Grupo Espanol de Tumores Neuroendocrinos
2015-05-11 PHASE2
NCT02779283 COMPLETED
Acute Lymphoblastic Leukemia; Acute Myeloid Leukemia
OHSU Knight Cancer Institute
2016-01-13 PHASE1
NCT02208128 UNKNOWN
Renal Cell Carcinoma
Heidelberg University
2014-05
NCT03379012 COMPLETED
Metastatic Renal Cell Carcinoma
Kidney Cancer Research Bureau
2016-02-08 PHASE2
NCT01005472 COMPLETED
Metastatic Melanoma
Jonsson Comprehensive Cancer Center
2008-12-01 PHASE1
NCT02626754 TERMINATED
Renal Cell Carcinoma
vghtpe user
2015-08-12 PHASE2
NCT01636908 COMPLETED
Cancer; Advanced Solid Tumors
Amsterdam UMC, location VUmc
2011-08
NCT02607332 COMPLETED
Gastrointestinal Stromal Tumors
Asan Medical Center
2015-11 PHASE2
NCT01190241 TERMINATED
Advanced Solid Tumors; Inoperable; Metastasis
Amsterdam UMC, location VUmc
2010-08
NCT02446795 UNKNOWN
Renal Cell Carcinoma; Kidney Cancer
Consorzio Oncotech
2016-11 PHASE1; PHASE2
NCT02623127 COMPLETED
Thymic Carcinoma
Seoul National University Hospital
2015-10 PHASE2
NCT01731925 UNKNOWN
Carcinoid Tumors
GERCOR - Multidisciplinary Oncology Cooperative Group
2013-01-07 PHASE2
NCT03456401 TERMINATED
Renal Cancer Cell
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
2014-11 PHASE2
NCT01499121 COMPLETED
Clear Cell, Metastatic Renal Cell Carcinoma
Sunnybrook Health Sciences Centre
2012-05 PHASE2
NCT01551459 COMPLETED
Metastatic Uveal Melanoma
The Clatterbridge Cancer Centre NHS Foundation Trust
2010-10 PHASE2
NCT02889328 COMPLETED
Gastrointestinal Stromal Tumors (GISTs)
Asan Medical Center
2016-09 PHASE2
NCT01396148 COMPLETED
Gastrointestinal Stromal Tumors
Pfizer
2012-06 PHASE2
NCT01829217 COMPLETED
Lung Cancer
Dana-Farber Cancer Institute
2013-05 PHASE2
NCT02386111 TERMINATED
Carcinoma, Renal Cell; Kidney Diseases; Kidney Neoplasms; Urogenital Neoplasms; Urologic Diseases; Urologic Neoplasms; Neoplasms; Neoplasms by Histologic Type; Clear-cell Metastatic Renal Cell Carcinoma
Celldex Therapeutics
2015-05 PHASE1
NCT02560012 TERMINATED
Carcinoma, Renal Cell
The University of Texas Health Science Center, Houston
2016-01-04 PHASE2
NCT01164202 COMPLETED
Liver Cancer
Federation Francophone de Cancerologie Digestive
2010-07 PHASE2; PHASE3
NCT02231749 COMPLETED
Advanced Renal Cell Carcinoma; Metastatic Renal Cell Carcinoma
Bristol-Myers Squibb
2014-10-16 PHASE3
NCT02074878 TERMINATED
Breast Cancer
Mothaffar Rimawi
2014-06 PHASE1
NCT01784978 TERMINATED
Metastatic Renal Cell Carcinoma
Associació per a la Recerca Oncologica, Spain
2013-02-12 PHASE2
NCT02013089 UNKNOWN
Gastrointestinal Cancers
Sun Yat-sen University
2013-12
NCT01620216 TERMINATED
Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome; Chronic Myelomonocytic Leukemia; Recurrent Acute Lymphoblastic Leukemia; Recurrent Acute Myeloid Leukemia; Refractory Acute Lymphoblastic Leukemia; Refractory Acute Myeloid Leukemia
OHSU Knight Cancer Institute
2012-05-11 PHASE2
NCT01803503 UNKNOWN
Solid Tumors; Breast Cancer; Non-small Cell Lung Cancer; Prostate Cancer; Gastric Cancer
National University Hospital, Singapore
2013-05 PHASE2
NCT02398552 UNKNOWN
Metastatic Renal Cell Carcinoma
Peking University Cancer Hospital & Institute
2015-03 PHASE2
NCT00381641 COMPLETED
Differentiated Thyroid Gland Carcinoma; Recurrent Thyroid Gland Carcinoma; Refractory Thyroid Gland Carcinoma; Stage III Thyroid Gland Follicular Carcinoma AJCC v7; Stage III Thyroid Gland Medullary Carcinoma AJCC v7; Stage IV Thyroid Gland Follicular Carcinoma AJCC v7; Stage IV Thyroid Gland Medullary Carcinoma AJCC v7; Stage IV Thyroid Gland Papillary Carcinoma AJCC v7; Stage IVA Thyroid Gland Follicular Carcinoma AJCC v7; Stage IVA Thyroid Gland Medullary Carcinoma AJCC v7; Stage IVA Thyroid Gland Papillary Carcinoma AJCC v7; Stage IVB Thyroid Gland Follicular Carcinoma AJCC v7; Stage IVB Thyroid Gland Medullary Carcinoma AJCC v7; Stage IVB Thyroid Gland Papillary Carcinoma AJCC v7; Stage IVC Thyroid Gland Follicular Carcinoma AJCC v7; Stage IVC Thyroid Gland Medullary Carcinoma AJCC v7; Stage IVC Thyroid Gland Papillary Carcinoma AJCC v7; Thyroid Gland Oncocytic Carcinoma; Unresectable Thyroid Gland Carcinoma
National Cancer Institute (NCI)
2006-08-29 PHASE2
NCT02164240 COMPLETED
Gastrointestinal Stromal Tumor
Dana-Farber Cancer Institute
2014-07 PHASE1
NCT02928575 UNKNOWN
Glioblastoma Multiforme
Bassam Abdulkarim
2012-08 PHASE2
NCT01176799 UNKNOWN
Breast Cancer
National University Hospital, Singapore
2010-08 PHASE2
NCT02072031 UNKNOWN
Anlotinib; RCC
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2013-12 PHASE2
NCT01907607 COMPLETED
Advanced Gastrointestinal Stromal Tumors
Institut Bergonié
2014-02 PHASE2
NCT01718327 COMPLETED
Unresectable and Advanced Cholangiocarcinoma
GERCOR - Multidisciplinary Oncology Cooperative Group
2011-09-01 PHASE2
NCT01984242 COMPLETED
Renal Cell Carcinoma
Hoffmann-La Roche
2014-01-08 PHASE2
NCT00400114 COMPLETED
Esophageal Cancer
University Health Network, Toronto
2006-09-25 PHASE2
NCT02071641 TERMINATED
Metastatic Renal Cell Carcinoma
Amsterdam UMC, location VUmc
2012-10 PHASE2
NCT00794950 COMPLETED
Urinary Tract Urothelial Carcinoma
University of Michigan
2009-01 PHASE2
NCT02268435 WITHDRAWN
Gastrointestinal Stromal Tumors
Asan Medical Center
2015-03 PHASE1
NCT01468688 COMPLETED
3rd Line GIST
Novartis Pharmaceuticals
2012-04-20 PHASE1
NCT01308034 COMPLETED
Non GIST Sarcomas
Centre Leon Berard
2011-03 PHASE1
NCT01835158 COMPLETED
Clear Cell Renal Cell Carcinoma; Metastatic Kidney Carcinoma; Stage III Renal Cell Cancer AJCC v7; Stage IV Renal Cell Cancer AJCC v7
National Cancer Institute (NCI)
2013-07-08 PHASE2
NCT00375674 COMPLETED
Kidney Neoplasms
Pfizer
2007-08-01 PHASE3
NCT01514448 COMPLETED
Metastatic Renal Cell Carcinoma (mRCC)
Novartis Pharmaceuticals
2012-05-21 PHASE4
NCT01525550 COMPLETED
Well-differentiated Pancreatic Neuroendocrine Tumor
Pfizer
2012-06-06 PHASE4
NCT01472081 COMPLETED
Renal Cell Carcinoma; Clear-cell Metastatic Renal Cell Carcinoma
Bristol-Myers Squibb
2012-02-09 PHASE1
NCT02380625 UNKNOWN
Ebola Virus Disease
Clinical Research Management, Inc.
2015-04 PHASE1; PHASE2
NCT01824615 COMPLETED
Ovarian Cancer; Adverse Effects
Cathay General Hospital
2013-01 PHASE2
NCT02400385 WITHDRAWN
Melanoma
California Pacific Medical Center Research Institute
2014-10 PHASE2
NCT02324803 UNKNOWN
Self Efficacy; Adverse Drug Event; Carcinoma, Renal Cell
Southern China Urology Cancer Consortium
2014-07 PHASE2
NCT01061411 COMPLETED
Clear Cell Sarcoma of the Kidney; Recurrent Renal Cell Carcinoma; Stage III Renal Cell Cancer; Stage IV Renal Cell Cancer
Roswell Park Cancer Institute
2010-02-06 PHASE1
NCT01216371 TERMINATED
Renal Cell Carcinoma; Pulmonary Metastases
Association of Urologic Oncology (AUO)
2010-10 PHASE2
NCT01402817 TERMINATED
Neurofibromatosis; NF1; Plexiform Neurofibromas
Indiana University
2012-03 PHASE2
NCT00326898 COMPLETED
Clear Cell Renal Cell Carcinoma; Stage I Renal Cell Cancer AJCC v6 and v7; Stage II Renal Cell Cancer AJCC v7; Stage III Renal Cell Cancer AJCC v7
National Cancer Institute (NCI)
2006-04-24 PHASE3
NCT01396408 ACTIVE_NOT_RECRUITING
Advanced Rare Tumours
Canadian Cancer Trials Group
2012-02-09 PHASE2
NCT01265901 COMPLETED
Metastatic Renal Cell Carcinoma
Immatics Biotechnologies GmbH
2010-12 PHASE3
NCT01402089 COMPLETED
Non Small-cell Lung Cancer; Renal-cell Cancer; Gastrointestinal Stroma Tumor
Markus Joerger
2012-01 PHASE4
NCT01389583 UNKNOWN
Gastrointestinal Stromal Tumor
National Health Research Institutes, Taiwan
2011-10 PHASE2
NCT00519896 COMPLETED
Recurrent Thyroid Cancer; Stage IVA Follicular Thyroid Cancer; Stage IVA Papillary Thyroid Cancer; Stage IVB Follicular Thyroid Cancer; Stage IVB Papillary Thyroid Cancer; Stage IVC Follicular Thyroid Cancer; Stage IVC Papillary Thyroid Cancer; Thyroid Gland Medullary Carcinoma
University of Washington
2007-07 PHASE2
NCT00903175 COMPLETED
Renal Cell Carcinoma
Novartis Pharmaceuticals
2009-10 PHASE2
NCT00465179 COMPLETED
Renal Cell Cancer; Kidney Cancer
M.D. Anderson Cancer Center
2007-03 PHASE2
NCT01108445 COMPLETED
Advanced Non-clear Cell Renal Cell Carcinoma
Duke University
2010-09 PHASE2
NCT01524848 COMPLETED
Gastrointestinal Stromal Tumors
Scandinavian Sarcoma Group
2012-02 PHASE2
NCT00631527 COMPLETED
Prostate Cancer
M.D. Anderson Cancer Center
2008-02 PHASE1
NCT00912912 TERMINATED
Genitourinary Disease
M.D. Anderson Cancer Center
2009-05 PHASE2
NCT01034878 COMPLETED
Carcinoma, Renal Cell
Istituto Clinico Humanitas
2009-12 PHASE2
NCT00943839 COMPLETED
Kidney Cancer
Centre Antoine Lacassagne
2009-02
NCT01498835 COMPLETED
Soft Tissue Sarcoma
Heidelberg University
2012-02 PHASE1
NCT01089088 COMPLETED
Bladder Cancer; Transitional Cell Cancer of the Renal Pelvis and Ureter; Urethral Cancer
Cardiff University
2009-04 PHASE2
NCT00589784 COMPLETED
CNS Cancer; Meningioma; Intracranial Hemangiopericytoma; Hemangioblastoma; Neurofibromatosis
Memorial Sloan Kettering Cancer Center
2007-10 PHASE2
NCT01850147 UNKNOWN
Cancer; Lung Cancer
Chinese Academy of Medical Sciences
2013-03 PHASE2
NCT00694096 COMPLETED
Renal Cell Cancer
University of Utah
2007-09 PHASE1
NCT00734851 TERMINATED
Prostate Cancer
Duke University
2008-12 PHASE2
NCT01391130 TERMINATED
Metastatic Clear Cell Renal Cell Carcinoma
Eli Lilly and Company
2011-08 PHASE2
NCT01054911 TERMINATED
Tumor
University of Alabama at Birmingham
2009-10
NCT00577382 COMPLETED
Mucosal Lentiginous Melanoma; Acral Lentiginous Malignant Melanoma
Dana-Farber Cancer Institute
2007-08 PHASE2
NCT00428220 COMPLETED
Metastatic Breast Cancer; Advanced Breast Cancer; Metastatic Castration Resistant Prostate Cancer; Metastatic Renal Cell Cancer; Non-Small Cell Lung Cancer; Thyroid Cancer; Advanced/Metastatic Non-Small Cell Lung Cancer; Advanced Gastric Cancer; Gastrointestinal Stromal Tumor; Hepatocellular Carcinoma; Pancreatic Islet Cell Carcinoma; Pancreatic Neuroendocrine Tumor
Pfizer
2007-07
NCT01122615 COMPLETED
Renal Cell Cancer; Kidney Cancer
M.D. Anderson Cancer Center
2010-05 PHASE1
NCT01289028 COMPLETED
Gastrointestinal Stromal Tumors
Novartis Pharmaceuticals
2008-11 PHASE3
NCT00463060 COMPLETED
Cancer
Icahn School of Medicine at Mount Sinai
2007-01 PHASE1; PHASE2
NCT00747305 TERMINATED
Kidney Cancer
Harry Drabkin
2008-10 PHASE1
NCT01381822 UNKNOWN
Advanced Renal Cell Carcinoma; Gastrointestinal Stromal Tumors; Pancreatic Neuroendocrine Tumors
Threshold Pharmaceuticals
2011-06 PHASE1
NCT00570882 COMPLETED
Metastatic Renal Cell Carcinoma
Asan Medical Center
2007-10 PHASE2
NCT00499135 COMPLETED
Adult Solid Neoplasm; Clear Cell Renal Cell Carcinoma; Recurrent Renal Cell Carcinoma; Stage III Renal Cell Cancer; Stage IV Renal Cell Cancer
National Cancer Institute (NCI)
2007-05-22 PHASE1
NCT00979992 COMPLETED
Ovarian Clear Cell Adenocarcinoma; Recurrent Ovarian Carcinoma
National Cancer Institute (NCI)
2010-04-19 PHASE2
NCT00981890 COMPLETED
Brain Metastases
University Health Network, Toronto
2009-07 PHASE1
NCT00793871 COMPLETED
Gastrointestinal Neoplasms, Gastrointestinal Stromal Tumors
Pfizer
2008-11 PHASE4
NCT01323400 COMPLETED
GIST
Centre Leon Berard
2011-03 PHASE2
NCT01740154 TERMINATED
Fatigue; Recurrent Renal Cell Cancer; Stage IV Renal Cell Cancer
Case Comprehensive Cancer Center
2012-09
NCT00982657 TERMINATED
Solid Tumor
Pfizer
2009-09 PHASE2
NCT00853125 TERMINATED
Kidney Cancer
Rutgers, The State University of New Jersey
2009-02 PHASE2
NCT01306045 COMPLETED
Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell Lung; Carcinoma, Thymic
National Cancer Institute (NCI)
2011-02-08 PHASE2
NCT01502228 TERMINATED
Renal Cell Carcinoma
Indiana University
2011-10
NCT01243359 COMPLETED
Clear Cell Renal Cell Carcinoma; Recurrent Renal Cell Cancer; Stage I Renal Cell Cancer; Stage II Renal Cell Cancer; Stage III Renal Cell Cancer; Stage IV Renal Cell Cancer; Unspecified Adult Solid Tumor, Protocol Specific
National Cancer Institute (NCI)
2010-10 PHASE1
NCT01673386 TERMINATED
Metastatic Renal Cell Carcinoma
AVEO Pharmaceuticals, Inc.
2012-07 PHASE2
NCT00556049 COMPLETED
Renal Cell Carcinoma; Neoplasm Metastases
Massachusetts General Hospital
2007-12 PHASE2
NCT01462695 COMPLETED
Childhood Cerebellar Anaplastic Astrocytoma; Childhood Cerebral Anaplastic Astrocytoma; Childhood Cerebral Astrocytoma; Childhood Infratentorial Ependymoma; Childhood Mixed Glioma; Childhood Oligodendroglioma; Childhood Supratentorial Ependymoma; Recurrent Childhood Cerebellar Astrocytoma; Recurrent Childhood Cerebral Astrocytoma; Recurrent Childhood Ependymoma; Recurrent Childhood Subependymal Giant Cell Astrocytoma
National Cancer Institute (NCI)
2012-01 PHASE2
NCT01215578 TERMINATED
Neuroendocrine Tumors; Pancreatic Neoplasms; Advanced Disease; Sunitinib
Assistance Publique - Hôpitaux de Paris
2008-10 PHASE2
NCT00693992 COMPLETED
Stage IIIB Lung Non-Small Cell Cancer AJCC v7; Stage IV Non-Small Cell Lung Cancer AJCC v7
National Cancer Institute (NCI)
2008-06-15 PHASE3
NCT01441388 WITHDRAWN
Carcinoma, Renal Cell; Glioblastoma; Carcinoma, Hepatocellular
Pfizer
2011-12 PHASE1
NCT00884676 COMPLETED
Unspecified Adult Solid Tumor, Protocol Specific
Jaime Merchan
2008-11 PHASE1
NCT01371201 COMPLETED
Malignant Progressive Pheochromocytoma and Paraganglioma (PPGL)
Gustave Roussy, Cancer Campus, Grand Paris
2011-12-22 PHASE2
NCT00732914 COMPLETED
Renal Cell Carcinoma
Sponsor GmbH
2009-01 PHASE3
NCT00702884 COMPLETED
Esophageal Cancer
Tony Bekaii-Saab
2008-06-30 PHASE2
NCT00570908 TERMINATED
Breast Cancer
Baylor Breast Care Center
2009-02 PHASE2
NCT00524186 TERMINATED
Esophageal Cancer; Gastric Cancer
Roswell Park Cancer Institute
2007-05 PHASE1
NCT01481870 UNKNOWN
Metastatic Renal Cell Carcinoma
Yamagata University
2010-01 PHASE3
NCT00887575 COMPLETED
Breast Cancer
SCRI Development Innovations, LLC
2009-06 PHASE1; PHASE2
NCT00783653 COMPLETED
Acute Myeloid Leukemia
Universitätsklinikum Hamburg-Eppendorf
2008-08 PHASE1; PHASE2
NCT00718562 COMPLETED
Gastrointestinal Stromal Tumors
Novartis Pharmaceuticals
2008-09 PHASE2
NCT00453154 COMPLETED
Extensive Stage Lung Small Cell Carcinoma; Recurrent Lung Small Cell Carcinoma
National Cancer Institute (NCI)
2007-03-15 PHASE1; PHASE2
NCT01158222 COMPLETED
Clear Cell Renal Cell Carcinoma; Stage IV Renal Cell Cancer
Case Comprehensive Cancer Center
2010-08-18 PHASE2
NCT01216657 TERMINATED
Chemo-refractory Melanoma
Krankenhaus Nordwest
2009-03 PHASE2
NCT01829841 COMPLETED
Renal Cell Cancer; Metastatic Renal Cell Cancer
Jiangsu HengRui Medicine Co., Ltd.
2011-05 PHASE2
NCT01440959 COMPLETED
Gastrointestinal Stromal Tumors
Asan Medical Center
2011-09 PHASE2
NCT01151852 COMPLETED
Gastrointestinal Stromal Tumors
Asan Medical Center
2010-06 PHASE3
NCT00891878 COMPLETED
Adenocarcinoma of the Gastroesophageal Junction; Esophageal Cancer
Alliance for Clinical Trials in Oncology
2009-08 PHASE2
NCT00886132 COMPLETED
Adenoid Cystic Carcinoma; Salivary Gland Cancer
University Health Network, Toronto
2007-01 PHASE2
NCT00788060 COMPLETED
Renal Cell Carcinoma
Daniel George, MD
2008-10 PHASE1
NCT00489944 UNKNOWN
Intraocular Melanoma
San Diego Pacific Oncology & Hematology Associates
2007-05 PHASE2
NCT00859456 TERMINATED
Sarcoma, Soft Tissue
Columbia University
2007-04 PHASE2
NCT01020630 COMPLETED
Adenocarcinoma
PD Dr Markus Möhler
2009-11 PHASE2
NCT00847015 COMPLETED
Bladder Cancer; Urinary Bladder
Memorial Sloan Kettering Cancer Center
2009-02 PHASE2
NCT00495872 COMPLETED
Solid Tumors
M.D. Anderson Cancer Center
2007-06 PHASE1
NCT00906360 TERMINATED
Metastatic Squamous Neck Cancer With Occult Primary Squamous Cell Carcinoma; Recurrent Metastatic Squamous Neck Cancer With Occult Primary; Recurrent Salivary Gland Cancer; Recurrent Squamous Cell Carcinoma of the Hypopharynx; Recurrent Squamous Cell Carcinoma of the Larynx; Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity; Recurrent Squamous Cell Carcinoma of the Nasopharynx; Recurrent Squamous Cell Carcinoma of the Oropharynx; Recurrent Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity; Recurrent Verrucous Carcinoma of the Larynx; Recurrent Verrucous Carcinoma of the Oral Cavity; Salivary Gland Squamous Cell Carcinoma; Stage III Salivary Gland Cancer; Stage III Squamous Cell Carcinoma of the Hypopharynx; Stage III Squamous Cell Carcinoma of the Larynx; Stage III Squamous Cell Carcinoma of the Lip and Oral Cavity; Stage III Squamous Cell Carcinoma of the Nasopharynx; Stage III Squamous Cell Carcinoma of the Oropharynx; Stage III Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity; Stage III Verrucous Carcinoma of the Larynx; Stage III Verrucous Carcinoma of the Oral Cavity; Stage IV Salivary Gland Cancer; Stage IV Squamous Cell Carcinoma of the Hypopharynx; Stage IV Squamous Cell Carcinoma of the Larynx; Stage IV Squamous Cell Carcinoma of the Lip and Oral Cavity; Stage IV Squamous Cell Carcinoma of the Nasopharynx; Stage IV Squamous Cell Carcinoma of the Oropharynx; Stage IV Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity; Stage IV Verrucous Carcinoma of the Larynx; Stage IV Verrucous Carcinoma of the Oral Cavity; Tongue Cancer; Untreated Metastatic Squamous Neck Cancer With Occult Primary
National Cancer Institute (NCI)
2008-07 PHASE1
NCT00672594 COMPLETED
Prostate Cancer; Prostatectomy
Duke University
2006-07 PHASE2
NCT00387920 COMPLETED
Central Nervous System Metastases; Childhood Central Nervous System Choriocarcinoma; Childhood Central Nervous System Embryonal Tumor; Childhood Central Nervous System Germ Cell Tumor; Childhood Central Nervous System Germinoma; Childhood Central Nervous System Mixed Germ Cell Tumor; Childhood Central Nervous System Teratoma; Childhood Central Nervous System Yolk Sac Tumor; Recurrent Childhood Central Nervous System Embryonal Tumor; Unspecified Childhood Solid Tumor, Protocol Specific
National Cancer Institute (NCI)
2006-10 PHASE1
NCT01122888 TERMINATED
Adult Giant Cell Glioblastoma; Adult Glioblastoma; Adult Gliosarcoma; Adult Solid Neoplasm; Recurrent Adult Brain Neoplasm
National Cancer Institute (NCI)
2009-12 PHASE1
NCT00513695 COMPLETED
Inflammatory Breast Cancer; Male Breast Cancer; Stage II Breast Cancer; Stage IIIA Breast Cancer; Stage IIIB Breast Cancer; Stage IIIC Breast Cancer
University of Washington
2007-06 PHASE2
NCT00821327 COMPLETED
Urothelial Cancer
US Oncology Research
2008-08 PHASE2
NCT00606008 COMPLETED
Anaplastic Astrocytoma; Glioblastoma
H. Lee Moffitt Cancer Center and Research Institute
2007-03 PHASE2
NCT01118351 TERMINATED
Recurrent Bladder Cancer; Transitional Cell Carcinoma of the Bladder
Case Comprehensive Cancer Center
2008-10 PHASE2
NCT00979966 COMPLETED
Non-clear Cell Renal Cell Cancer
Central European Society for Anticancer Drug Research
2009-07 PHASE2
NCT00864721 COMPLETED
Non Small Cell Lung Cancer
US Oncology Research
2009-02 PHASE2
NCT00357318 COMPLETED
Unspecified Adult Solid Tumor, Protocol Specific
National Cancer Institute (NCI)
2006-06 PHASE1
NCT00923117 TERMINATED
Glioblastoma Multiforme; Malignant Gliomas; Anaplastic Gliomas
National Cancer Institute (NCI)
2008-06 PHASE2
NCT01068769 COMPLETED
Gastrointestinal Stromal Tumor
Suzanne George, MD
2010-02 PHASE2
NCT00543049 COMPLETED
Platinum Refractory Epithelial Ovarian Cancer; Primary Cancer of the Peritoneum; Cancer of the Fallopian Tube
AGO Study Group
2007-09 PHASE2
NCT01147822 COMPLETED
Carcinoma, Renal Cell
Novartis Pharmaceuticals
2010-05-19 PHASE2
NCT00720941 COMPLETED
Carcinoma, Renal Cell
Novartis Pharmaceuticals
2008-08-14 PHASE3
NCT00768144 COMPLETED
Ovarian Cancer; Fallopian Tube Cancer; Peritoneal Cancer
Dana-Farber Cancer Institute
2008-09 PHASE2
NCT00678119 COMPLETED
Renal Cell Carcinoma
Argos Therapeutics
2008-01 PHASE2
NCT00777478 UNKNOWN
Colorectal Cancer
Radboud University Medical Center
2008-12 PHASE1
NCT01042795 TERMINATED
Urothelial Carcinoma; Bladder Cancer
University of Michigan
2009-09 PHASE2
NCT01238055 COMPLETED
Advanced Gastric Cancer
Samsung Medical Center
2008-11 PHASE2
NCT00631618 COMPLETED
Metastatic Melanoma
California Pacific Medical Center Research Institute
2007-09 PHASE2
NCT00510640 COMPLETED
Cancer; Thyroid Carcinoma
University Hospital, Bordeaux
2007-08 PHASE2
NCT00753727 UNKNOWN
Soft Tissue Sarcoma
Australasian Sarcoma Study Group
2008-09 PHASE1; PHASE2
NCT01258348 COMPLETED
Metastatic Renal Cell Cancer
Eli Lilly and Company
2008-07 PHASE1
NCT00620347 COMPLETED
Lung Cancer
National Cancer Center, Korea
2008-03 PHASE2
NCT00397488 COMPLETED
Bladder Cancer; Transitional Cell Cancer of the Renal Pelvis and Ureter; Urethral Cancer
Memorial Sloan Kettering Cancer Center
2006-09 PHASE2
NCT00619268 COMPLETED
Metastatic Renal Cell Carcinoma
Centre Leon Berard
2008-02 PHASE2
NCT00434109 COMPLETED
Neuroendocrine Tumor; Islet Cell Tumor
H. Lee Moffitt Cancer Center and Research Institute
2006-11 PHASE2
NCT01271712 COMPLETED
Gastrointestinal Stromal Tumors
Bayer
2011-01-04 PHASE3
NCT00392496 COMPLETED
Adult Diffuse Large Cell Lymphoma; Recurrent Adult Diffuse Large Cell Lymphoma; Stage IV Adult Diffuse Large Cell Lymphoma
National Cancer Institute (NCI)
2007-02 PHASE2
NCT01082809 COMPLETED
Advanced Biliary Tract Adenocarcinoma
Samsung Medical Center
2009-03 PHASE2
NCT00388037 COMPLETED
Recurrent Fallopian Tube Cancer; Recurrent Ovarian Epithelial Cancer; Recurrent Primary Peritoneal Cavity Cancer; Stage IIIA Fallopian Tube Cancer; Stage IIIA Ovarian Epithelial Cancer; Stage IIIA Primary Peritoneal Cavity Cancer; Stage IIIB Fallopian Tube Cancer; Stage IIIB Ovarian Epithelial Cancer; Stage IIIB Primary Peritoneal Cavity Cancer; Stage IIIC Fallopian Tube Cancer; Stage IIIC Ovarian Epithelial Cancer; Stage IIIC Primary Peritoneal Cavity Cancer; Stage IV Fallopian Tube Cancer; Stage IV Ovarian Epithelial Cancer; Stage IV Primary Peritoneal Cavity Cancer
National Cancer Institute (NCI)
2007-01 PHASE2
NCT00910039 TERMINATED
Cognitive/Functional Effects; Metastatic Cancer; Unspecified Adult Solid Tumor, Protocol Specific
Case Comprehensive Cancer Center
2009-04 PHASE2
NCT00967603 COMPLETED
Pancreatic Cancer
IRCCS San Raffaele
2008-02 PHASE2
NCT00474786 COMPLETED
Renal Cell Carcinoma
Pfizer
2007-09 PHASE3
NCT00392444 COMPLETED
Advanced Malignant Mesothelioma; Recurrent Malignant Mesothelioma
National Cancer Institute (NCI)
2007-02 PHASE2
NCT01286896 COMPLETED
Malignant Solid Tumour
The Netherlands Cancer Institute
2011-04-11 PHASE1
NCT00698815 COMPLETED
Recurrent Non-Small Cell Lung Carcinoma; Stage IIIB Non-Small Cell Lung Cancer AJCC v7; Stage IV Non-Small Cell Lung Cancer AJCC v7
National Cancer Institute (NCI)
2008-04-15 PHASE2
NCT00676650 TERMINATED
Prostatic Neoplasms
Pfizer
2008-07 PHASE3
NCT00798889 COMPLETED
Solid Tumors
Pfizer
2004-03
NCT00400569 COMPLETED
Liposarcoma; Leiomyosarcoma; Fibrosarcoma; Malignant Fibrous Histiocytoma
H. Lee Moffitt Cancer Center and Research Institute
2006-11 PHASE2
NCT01039519 COMPLETED
Gastrointestinal Stromal Tumor
Synta Pharmaceuticals Corp.
2010-01 PHASE2
NCT01069770 UNKNOWN
Clear Cell Renal Cell Carcinoma; Metastasis
Korean Urological Oncology Society
2009-07 PHASE2
NCT00699374 TERMINATED
Carcinoma, Hepatocellular
Pfizer
2008-07 PHASE3
NCT01024920 COMPLETED
Carcinoma, Renal Cell
Boehringer Ingelheim
2009-12-16 PHASE2
NCT01210053 UNKNOWN
Non-small Cell Lung Cancer
Third Military Medical University
2010-09 PHASE2
NCT01064310 COMPLETED
Carcinoma, Renal Cell
Novartis Pharmaceuticals
2010-05-17 PHASE3
NCT00975806 TERMINATED
Renal Cell Carcinoma
Celgene
2009-09-01 PHASE1; PHASE2
NCT00879619 TERMINATED
Prostate Cancer; Adenocarcinoma of the Prostate; Recurrent Prostate Cancer; Stage I Prostate Cancer; Stage III Prostate Cancer; Stage IV Prostate Cancer
John P. Fruehauf
2009-07 PHASE1; PHASE2
NCT00673504 COMPLETED
Pancreatic Cancer
Central European Society for Anticancer Drug Research
2008-04 PHASE2
NCT00480935 TERMINATED
Renal Cell Carcinoma
University Health Network, Toronto
2007-10 PHASE2
NCT00537056 COMPLETED
Kidney Neoplasms; Carcinoma, Renal Cell; Kidney (Renal Cell) Cancer
Stanford University
2007-10
NCT00931450 UNKNOWN
Breast Cancer
Institut Català d'Oncologia
2009-03 PHASE1; PHASE2
NCT00953446 TERMINATED
Renal Cell Carcinoma
Beth Israel Deaconess Medical Center
2010-06-15
NCT00372424 COMPLETED
Breast Cancer
Pfizer
2006-12 PHASE1
NCT01219751 UNKNOWN
Metastatic Renal Cell Carcinoma
Asan Medical Center
2008-06 PHASE2
NCT01506336 COMPLETED
Gastro Intestinal Stromal Tumor
AB Science
2008-10 PHASE2
NCT00451048 COMPLETED
Chronic Myelomonocytic Leukemia; de Novo Myelodysplastic Syndromes; Myelodysplastic Syndromes; Secondary Myelodysplastic Syndromes
National Cancer Institute (NCI)
2007-02 PHASE2
NCT00853372 COMPLETED
Advanced Renal Cell Carcinoma
Amgen
2009-05-28 PHASE2
NCT00453895 COMPLETED
Adrenocortical Carcinoma
University of Wuerzburg
2007-07 PHASE2
NCT00706706 COMPLETED
Carcinoma, Renal Cell
Pfizer
2008-07 PHASE4
NCT00729833 TERMINATED
Advanced Cancer; Advanced Solid Tumors
Pfizer
2008-09 PHASE1
NCT00705874 COMPLETED
Cancer
Progen Pharmaceuticals
2006-05 PHASE1
NCT00609622 TERMINATED
Colorectal Neoplasms
Pfizer
2008-04 PHASE2
NCT01548170 COMPLETED
Cancer
Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
2011-04 PHASE1
NCT00520533 TERMINATED
Renal Cell Carcinoma (RCC)
Ludwig Institute for Cancer Research
2008-02 PHASE1
NCT01121562 COMPLETED
Pancreatic Neuroendocrine Tumors
Pfizer
2010-07 PHASE2
NCT00486538 COMPLETED
Advanced Renal Cell Carcinoma
AbbVie (prior sponsor, Abbott)
2007-06 PHASE2
NCT00869011 UNKNOWN
Renal Cell Carcinoma
Charite University, Berlin, Germany
2009-12 PHASE3
NCT00890110 UNKNOWN
Renal Cell Cancer
Hadassah Medical Organization
2009-06 PHASE1; PHASE2
NCT00695292 COMPLETED
Small Cell Lung Cancer
SCRI Development Innovations, LLC
2008-06 PHASE2
NCT00890747 COMPLETED
Accelerated Phase Chronic Myelogenous Leukemia; Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome; Acute Undifferentiated Leukemia; Adult Acute Lymphoblastic Leukemia in Remission; Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities; Adult Acute Myeloid Leukemia With Del(5q); Adult Acute Myeloid Leukemia With Inv(16)(p13;q22); Adult Acute Myeloid Leukemia With t(15;17)(q22;q12); Adult Acute Myeloid Leukemia With t(16;16)(p13;q22); Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); Adult Grade III Lymphomatoid Granulomatosis; Adult Langerhans Cell Histiocytosis; Adult Nasal Type Extranodal NK/T-cell Lymphoma; Aggressive NK-cell Leukemia; AIDS-related Diffuse Large Cell Lymphoma; AIDS-related Diffuse Mixed Cell Lymphoma; AIDS-related Diffuse Small Cleaved Cell Lymphoma; AIDS-related Immunoblastic Large Cell Lymphoma; AIDS-related Lymphoblastic Lymphoma; AIDS-related Malignancies; AIDS-related Small Noncleaved Cell Lymphoma; Anaplastic Large Cell Lymphoma; Angioimmunoblastic T-cell Lymphoma; Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative; Chronic Eosinophilic Leukemia; Chronic Myelomonocytic Leukemia; Chronic Neutrophilic Leukemia; Chronic Phase Chronic Myelogenous Leukemia; Clear Cell Renal Cell Carcinoma; Cutaneous B-cell Non-Hodgkin Lymphoma; de Novo Myelodysplastic Syndromes; Essential Thrombocythemia; Extramedullary Plasmacytoma; Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue; Hepatosplenic T-cell Lymphoma; HIV Infection; HIV-associated Hodgkin Lymphoma; Intraocular Lymphoma; Isolated Plasmacytoma of Bone; Light Chain Deposition Disease; Mast Cell Leukemia; Myelodysplastic Syndrome With Isolated Del(5q); Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable; Myeloid/NK-cell Acute Leukemia; Nodal Marginal Zone B-cell Lymphoma; Noncutaneous Extranodal Lymphoma; Osteolytic Lesions of Multiple Myeloma; Peripheral T-cell Lymphoma; Plasma Cell Neoplasm; Polycythemia Vera; Post-transplant Lymphoproliferative Disorder; Previously Treated Myelodysplastic Syndromes; Primary Myelofibrosis; Primary Systemic Amyloidosis; Progressive Hairy Cell Leukemia, Initial Treatment; Prolymphocytic Leukemia; Recurrent Adult Acute Lymphoblastic Leukemia; Recurrent Adult Acute Myeloid Leukemia; Recurrent Adult Burkitt Lymphoma; Recurrent Adult Diffuse Large Cell Lymphoma; Recurrent Adult Diffuse Mixed Cell Lymphoma; Recurrent Adult Diffuse Small Cleaved Cell Lymphoma; Recurrent Adult Grade III Lymphomatoid Granulomatosis; Recurrent Adult Hodgkin Lymphoma; Recurrent Adult Immunoblastic Large Cell Lymphoma; Recurrent Adult Lymphoblastic Lymphoma; Recurrent Adult T-cell Leukemia/Lymphoma; Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma; Recurrent Grade 1 Follicular Lymphoma; Recurrent Grade 2 Follicular Lymphoma; Recurrent Grade 3 Follicular Lymphoma; Recurrent Mantle Cell Lymphoma; Recurrent Marginal Zone Lymphoma; Recurrent Mycosis Fungoides/Sezary Syndrome; Recurrent Renal Cell Cancer; Recurrent Small Lymphocytic Lymphoma; Refractory Chronic Lymphocytic Leukemia; Refractory Hairy Cell Leukemia; Refractory Multiple Myeloma; Relapsing Chronic Myelogenous Leukemia; Stage IV Renal Cell Cancer; T-cell Large Granular Lymphocyte Leukemia; Testicular Lymphoma; Unspecified Adult Solid Tumor, Protocol Specific; Waldenström Macroglobulinemia
National Cancer Institute (NCI)
2009-08 PHASE1
NCT00731211 COMPLETED
Renal Cell Carcinoma
SCRI Development Innovations, LLC
2008-09 PHASE2
NCT00864864 COMPLETED
Glioblastoma; Brain Tumor
Massachusetts General Hospital
2007-05 EARLY_PHASE1
NCT00792025 COMPLETED
Bladder Cancer; Transitional Cell Cancer of the Renal Pelvis and Ureter
Institut Curie
2008-12 PHASE2
NCT00330564 TERMINATED
Von Hippel-Lindau Syndrome; Renal Cell Carcinoma; Hemangioblastoma
M.D. Anderson Cancer Center
2006-05 PHASE2
NCT01215565 TERMINATED
Hepatocellular Carcinoma; Fibrolamellar Hepatocellular Carcinoma
Assistance Publique - Hôpitaux de Paris
2009-10 PHASE2
NCT00796861 TERMINATED
Ascites
Milton S. Hershey Medical Center
2007-05 PHASE2
NCT00748358 COMPLETED
Prostatic Neoplasms; Neoplasms, Hormone-Dependent; Tumor Markers, Biological; Survival Rate; Disease-Free Survival
Assistance Publique - Hôpitaux de Paris
2008-03 PHASE2
NCT00795171 UNKNOWN
Hormone Refractory Prostate Cancer
Medical University of Vienna
2008-11 PHASE2
NCT00616122 TERMINATED
Breast Cancer
University of California, San Francisco
2006-03-01 PHASE1; PHASE2
NCT00459979 COMPLETED
Kidney Cancer
Case Comprehensive Cancer Center
2007-03 PHASE2
NCT00961571 TERMINATED
Metastatic Colorectal Cancer
Georgetown University
2009-08 PHASE2
NCT00541008 COMPLETED
Kidney Cancer
UNICANCER
2007-09-05 PHASE2
NCT00673816 TERMINATED
Von Hippel-Lindau Syndrome
National Eye Institute (NEI)
2008-05 PHASE1; PHASE2
NCT01168440 COMPLETED
Von Hippel-Lindau Disease
Association Pour La Recherche des Thérapeutiques Innovantes en Cancérologie
2010-03 PHASE2
NCT00626509 UNKNOWN
Kidney Cancer
Gruppo Italiano Carcinoma Renale
2008-02 PHASE2
NCT00905021 TERMINATED
Metastatic Breast Cancer
Baylor Breast Care Center
2010-03 PHASE1; PHASE2
NCT00535379 UNKNOWN
Glioblastoma Multiforme
Medical University Innsbruck
2007-10 PHASE2
NCT00495625 TERMINATED
Liver Cancer
H. Lee Moffitt Cancer Center and Research Institute
2006-10 PHASE2
NCT01091207 COMPLETED
Gastrointestinal Stromal Tumors
Samsung Medical Center
2009-11 PHASE2
NCT01019798 UNKNOWN
Non Small Cell Lung Cancer
Taipei Medical University Hospital
2009-01 PHASE2
NCT00524316 TERMINATED
Liver Cancer
Roswell Park Cancer Institute
2007-04 PHASE2
NCT00814021 COMPLETED
Kidney Cancer; Metastatic Cancer
Institut Claudius Regaud
2009-04 PHASE2
NCT01118039 UNKNOWN
Bladder Cancer; Transitional Cell Cancer of the Renal Pelvis and Ureter; Urethral Cancer
Hospital del Mar
2006-07 PHASE2
NCT00437372 COMPLETED
Cancer; Head and Neck Cancer; Pelvic Cancer; Nervous System Neoplasms; Thoracic Neoplasms
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
2007-03 PHASE1
NCT01743300 COMPLETED
Healthy
Leiden University Medical Center
2007-07 PHASE1
NCT00824538 TERMINATED
Breast Cancer
University of California, San Francisco
2009-02 PHASE2
NCT00459875 COMPLETED
Kidney Cancer
Memorial Sloan Kettering Cancer Center
2007-03 PHASE2
NCT00474994 COMPLETED
Adult Malignant Fibrous Histiocytoma of Bone; Desmoid Tumor; Endometrial Cancer; Ovarian Cancer; Sarcoma; Small Intestine Cancer
Memorial Sloan Kettering Cancer Center
2007-04 PHASE2
NCT00521092 WITHDRAWN
AIDS-related Kaposi Sarcoma; Classic Kaposi Sarcoma
National Cancer Institute (NCI)
2009-01 PHASE2
NCT00430261 COMPLETED
Lung Cancer; Adenocarcinoma
Swedish Medical Center
2007-01 PHASE2
NCT00668863 COMPLETED
Unresectable or Metastatic Colorectal Cancer
Pfizer
2008-05 PHASE2
NCT00656669 COMPLETED
Breast Cancer
Indiana University
2008-04
NCT01024205 COMPLETED
Kidney Cancer
Barts and the London School of Medicine and Dentistry
2007-08 PHASE2
NCT00555620 COMPLETED
Stomach Neoplasms
Pfizer
2008-05 PHASE1
NCT00425386 COMPLETED
Kidney Cancer
OHSU Knight Cancer Institute
2006-08 PHASE2
NCT00953459 TERMINATED
Lung Cancer
European Organisation for Research and Treatment of Cancer - EORTC
2009-02 PHASE2
NCT00457392 COMPLETED
Carcinoma, Non-Small Cell Lung
Pfizer
2007-07 PHASE3
NCT00720148 COMPLETED
Solid Tumors
Emory University
2008-02 PHASE1
NCT00717587 UNKNOWN
Kidney Cancer
Abramson Cancer Center at Penn Medicine
2008-06 PHASE2
NCT00806663 COMPLETED
Metastatic Colorectal Cancer; Liver Metastases
Central European Society for Anticancer Drug Research
2008-08 PHASE2
NCT00471276 COMPLETED
Breast Neoplasms
Pfizer
2007-08 PHASE2
NCT00267748 COMPLETED
Carcinoma, Renal Cell
Pfizer
2005-12 PHASE2
NCT00462553 COMPLETED
Adenocarcinoma of the Pancreas; Recurrent Pancreatic Cancer; Stage III Pancreatic Cancer; Stage IV Pancreatic Cancer; Unspecified Adult Solid Tumor, Protocol Specific
National Cancer Institute (NCI)
2007-03 PHASE1
NCT00618319 COMPLETED
GIST
Biogen
2008-02 PHASE2
NCT00787787 TERMINATED
Adult Primary Hepatocellular Carcinoma; Advanced Adult Primary Liver Cancer; Localized Unresectable Adult Primary Liver Cancer; Recurrent Adult Primary Liver Cancer
University of Washington
2008-09 PHASE2
NCT00528619 COMPLETED
Neoplasms
Pfizer
2006-11 PHASE1
NCT00936832 WITHDRAWN
Colorectal Cancer; Metastatic Cancer
Federation Francophone de Cancerologie Digestive
2009-04 PHASE2
NCT00482755 COMPLETED
Breast Cancer
NCIC Clinical Trials Group
2009-04-08 PHASE2
NCT00526656 COMPLETED
Bladder Cancer
Case Comprehensive Cancer Center
2007-09 PHASE2
NCT00457691 COMPLETED
Metastatic Colorectal Cancer
Pfizer
2007-06 PHASE3
NCT00387335 COMPLETED
Metastatic Squamous Neck Cancer With Occult Primary Squamous Cell Carcinoma; Recurrent Metastatic Squamous Neck Cancer With Occult Primary; Recurrent Squamous Cell Carcinoma of the Hypopharynx; Recurrent Squamous Cell Carcinoma of the Larynx; Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity; Recurrent Squamous Cell Carcinoma of the Nasopharynx; Recurrent Squamous Cell Carcinoma of the Oropharynx; Recurrent Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity; Stage IV Squamous Cell Carcinoma of the Hypopharynx; Stage IV Squamous Cell Carcinoma of the Larynx; Stage IV Squamous Cell Carcinoma of the Lip and Oral Cavity; Stage IV Squamous Cell Carcinoma of the Nasopharynx; Stage IV Squamous Cell Carcinoma of the Oropharynx; Stage IV Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity
National Cancer Institute (NCI)
2006-08 PHASE2
NCT00730353 COMPLETED
Esophageal Cancer
Hoosier Cancer Research Network
2008-08 PHASE2
NCT00709995 COMPLETED
Metastatic Renal Cell Carcinoma
Eli Lilly and Company
2008-06-30 PHASE2
NCT00265798 ACTIVE_NOT_RECRUITING
Gastrointestinal Stromal Tumor
National Cancer Institute (NCI)
2005-09-14 PHASE2
NCT00393939 COMPLETED
Breast Neoplasms
Pfizer
2007-02 PHASE3
NCT00555256 COMPLETED
Non-Small Cell Lung Cancer
Washington University School of Medicine
2007-11 PHASE1
NCT00422344 COMPLETED
Renal Cell Carcinoma; Kidney Cancer
Memorial Sloan Kettering Cancer Center
2006-10 PHASE1
NCT00581789 COMPLETED
Non Small Cell Lung Cancer
University of Wisconsin, Madison
2007-08 PHASE1
NCT00265317 COMPLETED
Carcinoma, Non-Small-Cell Lung
Pfizer
2006-06 PHASE2
NCT00891475 COMPLETED
Carcinoma, Renal Cell
Kidney Cancer Research Bureau
2008-05 PHASE1; PHASE2
NCT01070706 COMPLETED
Breast Cancer
Jungsil Ro
2009-03 PHASE1; PHASE2
NCT00662025 COMPLETED
Advanced/Metastatic Breast Cancer
Pfizer
2008-04 PHASE2
NCT00555672 COMPLETED
Stomach Neoplasms
Pfizer
2008-08 PHASE1
NCT00435409 COMPLETED
Breast Neoplasms
Pfizer
2007-02 PHASE3
NCT00616109 COMPLETED
Extensive-Stage Small Cell Lung Cancer
University of Michigan Rogel Cancer Center
2007-09 PHASE2
NCT00372775 COMPLETED
Non-Small Cell Lung Cancer
Pfizer
2007-03 PHASE2
NCT00732992 COMPLETED
Neoplasm, Malignant
Pfizer
2008-08 PHASE1
NCT00372567 TERMINATED
Gastrointestinal Stromal Tumor
Pfizer
2007-06 PHASE3
NCT00373113 TERMINATED
Breast Neoplasms
Pfizer
2006-11 PHASE3
NCT00573404 TERMINATED
Gastrointestinal Stromal Tumor
Vanderbilt-Ingram Cancer Center
2007-07 PHASE1
NCT00556205 WITHDRAWN
Renal Cell Carcinoma
Massachusetts General Hospital
2009-09 PHASE2
NCT00663559 COMPLETED
Carcinoma Renal Cells
Spanish Oncology Genito-Urinary Group
2008-02 PHASE2
NCT00818350 UNKNOWN
Urinary Bladder Neoplasms
Campania Younger Oncologists Association
2009-01 PHASE1; PHASE2
NCT00849186 COMPLETED
Kidney Cancer
Roswell Park Cancer Institute
2007-08
NCT00417885 TERMINATED
Breast Neoplasms
Pfizer
2007-06 PHASE1; PHASE2
NCT00631410 COMPLETED
Colorectal Neoplasms
Pfizer
2008-01 PHASE1
NCT00411151 COMPLETED
Gastric Adenocarcinoma; Barrett Esophagus
Johannes Gutenberg University Mainz
2006-12 PHASE2
NCT00553696 COMPLETED
Stomach Neoplasms
Pfizer
2007-11 PHASE1
NCT00678288 TERMINATED
Carcinoma, Renal Cell
Bayer
2008-04 PHASE2
NCT00499473 COMPLETED
Adult Anaplastic Astrocytoma; Adult Diffuse Astrocytoma; Adult Giant Cell Glioblastoma; Adult Glioblastoma; Adult Gliosarcoma; Adult Mixed Glioma; Adult Oligodendroglioma; Adult Pineal Gland Astrocytoma
National Cancer Institute (NCI)
2007-06 PHASE2
NCT00599313 COMPLETED
Metastatic Prostate Cancer
US Oncology Research
2007-03 PHASE2
NCT00371553 COMPLETED
Relapsed or Cisplatin-Refractory Germ Cell Cancer
British Columbia Cancer Agency
2006-11 PHASE2
NCT00373256 COMPLETED
Breast Neoplasms
Pfizer
2006-11 PHASE3
NCT00570635 COMPLETED
Gastrointestinal Stromal Tumors; Gastrointestinal Neoplasms
Exelixis
2007-12 PHASE2
NCT00688766 TERMINATED
Gastrointestinal Stromal Tumors
Infinity Pharmaceuticals, Inc.
2008-08 PHASE3
NCT00428597 TERMINATED
Carcinoma, Islet Cell; Carcinoma, Pancreas
Pfizer
2007-06 PHASE3
NCT00338884 COMPLETED
Carcinoma, Renal Cell
Pfizer
2006-09 PHASE2
NCT00482911 TERMINATED
Intraocular Melanoma; Malignant Conjunctival Neoplasm
National Institutes of Health Clinical Center (CC)
2007-04 PHASE2
NCT00904657 COMPLETED
Blood Pressure
University of Cologne
2008-10 PHASE1
NCT00113516 COMPLETED
Non-small Cell Lung Cancer
Pfizer
2005-09 PHASE2
NCT00514137 COMPLETED
Refractory Multiple Myeloma; Stage I Multiple Myeloma; Stage II Multiple Myeloma; Stage III Multiple Myeloma
National Cancer Institute (NCI)
2007-09 PHASE2
NCT00389974 COMPLETED
Cervical Adenocarcinoma; Cervical Adenosquamous Cell Carcinoma; Cervical Squamous Cell Carcinoma; Recurrent Cervical Cancer; Stage IVB Cervical Cancer
National Cancer Institute (NCI)
2007-01 PHASE2
NCT00511849 COMPLETED
Neoplasms
Pfizer
2005-11 PHASE1
NCT00387426 TERMINATED
Accelerated Phase Chronic Myelogenous Leukemia; Acute Undifferentiated Leukemia; Adult Acute Lymphoblastic Leukemia in Remission; Adult Acute Myeloid Leukemia in Remission; Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities; Adult Acute Myeloid Leukemia With Inv(16)(p13;q22); Adult Acute Myeloid Leukemia With t(15;17)(q22;q12); Adult Acute Myeloid Leukemia With t(16;16)(p13;q22); Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative; Blastic Phase Chronic Myelogenous Leukemia; Chronic Myelomonocytic Leukemia; Chronic Phase Chronic Myelogenous Leukemia; Mast Cell Leukemia; Meningeal Chronic Myelogenous Leukemia; Primary Myelofibrosis; Progressive Hairy Cell Leukemia, Initial Treatment; Prolymphocytic Leukemia; Recurrent Adult Acute Lymphoblastic Leukemia; Recurrent Adult Acute Myeloid Leukemia; Refractory Chronic Lymphocytic Leukemia; Refractory Hairy Cell Leukemia; Relapsing Chronic Myelogenous Leukemia; Secondary Acute Myeloid Leukemia; Stage I Chronic Lymphocytic Leukemia; Stage II Chronic Lymphocytic Leukemia; Stage III Chronic Lymphocytic Leukemia; Stage IV Chronic Lymphocytic Leukemia; T-cell Large Granular Lymphocyte Leukemia; Untreated Adult Acute Lymphoblastic Leukemia; Untreated Adult Acute Myeloid Leukemia; Untreated Hairy Cell Leukemia
National Cancer Institute (NCI)
2006-09 PHASE2
NCT00399152 COMPLETED
Renal Cancer; GIST
AEterna Zentaris
2006-10 PHASE1
NCT00444314 COMPLETED
Metastatic Renal Cell Carcinoma
CASI pharmaceuticals, Inc.
2007-02 PHASE2
NCT00398112 COMPLETED
B-cell Chronic Lymphocytic Leukemia; Recurrent Small Lymphocytic Lymphoma; Refractory Chronic Lymphocytic Leukemia
National Cancer Institute (NCI)
2007-08 PHASE2
NCT00599924 COMPLETED
Colorectal Neoplasms; Neoplasms
Pfizer
2005-09 PHASE1
NCT00453310 COMPLETED
Extragonadal Germ Cell Tumor; Ovarian Cancer; Teratoma; Testicular Germ Cell Tumor
Memorial Sloan Kettering Cancer Center
2007-03 PHASE2
NCT00291577 COMPLETED
Breast Neoplasms
Pfizer
2006-07 PHASE1
NCT00514228 COMPLETED
Liver Cancer
Swiss Cancer Institute
2007-07 PHASE2
NCT00748163 WITHDRAWN
Lung Cancer
Masonic Cancer Center, University of Minnesota
2008-08 PHASE2
NCT00462982 COMPLETED
Kidney Cancer; Melanoma (Skin); Metastatic Cancer
Memorial Sloan Kettering Cancer Center
2007-03 PHASE2
NCT00457743 COMPLETED
Gastrointestinal Stromal Tumors
Pfizer
2005-01 PHASE1; PHASE2
NCT00471328 COMPLETED
Gastrointestinal Stromal Tumors
Novartis Pharmaceuticals
2007-03 PHASE3
NCT00402415 TERMINATED
Tumors
Yale University
2006-02 PHASE1
NCT00782834 TERMINATED
Gastrointestinal Stromal Tumors
Fox Chase Cancer Center
2008-07 PHASE2
NCT00617253 COMPLETED
Cancer; Renal Cell Carcinoma
Novo Nordisk A/S
2007-07-12 PHASE2
NCT00299741 COMPLETED
Prostate Cancer
Massachusetts General Hospital
2006-03 PHASE2
NCT00226811 COMPLETED
Stomach Neoplasms
Pfizer
2006-01 PHASE2
NCT00434356 TERMINATED
Metastatic Breast Cancer
Genentech, Inc.
2007-03 PHASE2
NCT00522249 TERMINATED
Carcinoma, Renal Cell
The Methodist Hospital Research Institute
2007-05 PHASE1; PHASE2
NCT00421512 COMPLETED
Metastatic Renal Cell Carcinoma; Kidney Cancer
Memorial Sloan Kettering Cancer Center
2006-03 PHASE1
NCT00434226 TERMINATED
Non-Small Cell Lung Cancer
Genentech, Inc.
2007-03 PHASE2
NCT00583063 COMPLETED
Solid Tumors
University of Chicago
2007-10 EARLY_PHASE1
NCT00247676 COMPLETED
Liver Neoplasms; Unresectable Hepatocellular Carcinoma
Pfizer
2006-02 PHASE2
NCT00491738 TERMINATED
Renal Cell Carcinoma
Genentech, Inc.
2007-08 PHASE2
NCT00712504 COMPLETED
Advanced Solid Tumors; Non Small Cell Lung Cancer
Pfizer
2004-07 PHASE1
NCT00137423 COMPLETED
Carcinoma, Renal Cell Metastasis
Pfizer
2005-05 PHASE2
NCT00397787 COMPLETED
Acinar Cell Adenocarcinoma of the Pancreas; Duct Cell Adenocarcinoma of the Pancreas; Recurrent Pancreatic Cancer; Stage IV Pancreatic Cancer
National Cancer Institute (NCI)
2006-11 PHASE2
NCT00113529 COMPLETED
Carcinoma, Renal Cell
Pfizer
2004-10 PHASE1; PHASE2
NCT00496223 TERMINATED
Melanoma
H. Lee Moffitt Cancer Center and Research Institute
2006-09 PHASE1; PHASE2
NCT00378911 COMPLETED
Recurrent Uterine Sarcoma; Uterine Leiomyosarcoma
National Cancer Institute (NCI)
2006-10 PHASE2
NCT00092001 COMPLETED
Carcinoma, Non-Small-Cell Lung
Pfizer
2005-01 PHASE2
NCT00089648 COMPLETED
Carcinoma, Renal Cell
Pfizer
2004-12 PHASE2
NCT00056693 COMPLETED
Neuroendocrine Tumors
Pfizer
2003-04 PHASE2
NCT00417677 TERMINATED
Renal Cell Carcinoma
Wyeth is now a wholly owned subsidiary of Pfizer
2007-03 PHASE1; PHASE2
NCT00861419 COMPLETED
Advanced Solid Tumors
Amgen
2005-12 PHASE1
NCT00550810 UNKNOWN
Prostate Cancer; Hormone Refractory
Alberta Health services
2007-10 PHASE2
NCT01070186 WITHDRAWN
Renal Cell Carcinoma
Jonsson Comprehensive Cancer Center
2010-10 PHASE2

(data from https://clinicaltrials.gov, updated on 2023-09-13)

Check the Sunitinib (SU-11248) product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Compliance for Clinical Use

Mechanism and Biochemical Profile

Sunitinib functions as a potent multi-targeted receptor tyrosine kinase inhibitor that selectively binds VEGFR2, PDGFRβ, and c-Kit, thereby suppressing autophosphorylation and blocking downstream intracellular signaling cascades. This kinase inhibition impairs tumor angiogenesis and promotes endothelial apoptosis, providing the mechanistic foundation for its demonstrated clinical efficacy in renal cell carcinoma and gastrointestinal stromal tumors.

Appendix RUO and cGMP Quality Standards

Quality Dimension RUO (Research Use Only) cGMP (Current Good Manufacturing Practice)
Clinical Applicability Prohibited in human clinical trials or medical diagnostics. Mandatory for human clinical trials (Phase I–III) and therapies.
Regulatory Status Non-regulated grade; exempt from drug manufacturing laws. Legally enforced by health authorities (e.g., FDA, EMA, NMPA).
Facility Environment Unclassified analytical or research laboratories. Validated Cleanrooms (ISO Class 5–8) with continuous monitoring.
Quality Control Basic purity and activity testing. Rigorous safety release testing (Sterility, Endotoxin, Mycoplasma).
Process Validation Basic equipment calibration; no process validation required. Full qualification (IQ/OQ/PQ) and complete batch records.
Quality Assurance Vendor self-declared without required formal QMS. Mandatory QA/QC unit, Change Control, CAPA, and vendor audits.
Regulatory Impact High risk of IND rejection if used as a critical raw material. Required for IND/NDA filings, supported by Drug Master Files (DMF).

Footnotes

Regulatory Note: Governed by FDA (21 CFR Parts 210/211/312), EMA (EudraLex Vol 4), ICH Guidelines (E6/Q7/Q9/Q10), and compendial standards (USP <71>/<85>/<1043>).

Note: Technical data last updated: Sep 1, 2026.