Sunitinib has been extensively evaluated across numerous clinical trials spanning Phase 1 to Phase 3, focusing primarily on solid tumors such as renal cell carcinoma, gastrointestinal stromal tumors, non-small cell lung cancer, prostate neoplasms, and breast cancer. Sponsored by pharmaceutical entities and academic institutions, these investigations encompass actively recruiting, completed, terminated, and withdrawn protocols. Recent research evaluates sunitinib in combination regimens for renal cell carcinoma and MET-driven papillary renal cell carcinoma.
| NCT Number | Recruitment | Conditions | Sponsor/Collaborators | Start Date | Phases |
|---|---|---|---|---|---|
| NCT06032728 | NOT_YET_RECRUITING | Renal Cell Carcinoma |
First Affiliated Hospital, Sun Yat-Sen University |
2023-10-01 | |
| NCT06726421 | RECRUITING | Renal Cell Carcinoma (Kidney Cancer); Kidney Cancer Metastatic; Renal Cell Carcinoma Metastatic |
Sun Yat-sen University |
2024-09-18 | PHASE3 |
| NCT03899155 | RECRUITING | Cancer |
Bristol-Myers Squibb |
2019-08-09 | PHASE2 |
| NCT03768063 | ACTIVE_NOT_RECRUITING | Cancer |
Hoffmann-La Roche |
2019-02-28 | PHASE3 |
| NCT07218926 | RECRUITING | Gastrointestinal Neoplasms |
GlaxoSmithKline |
2025-12-03 | PHASE3 |
| NCT07477457 | RECRUITING | Osteosarcoma; Metastasis |
Memorial Sloan Kettering Cancer Center |
2026-03-11 | PHASE2 |
| NCT02693535 | RECRUITING | Lymphoma, Non-Hodgkin; Multiple Myeloma; Advanced Solid Tumors |
American Society of Clinical Oncology |
2016-03-14 | PHASE2 |
| NCT00329043 | ACTIVE_NOT_RECRUITING | Prostate Cancer |
M.D. Anderson Cancer Center |
2006-05-15 | PHASE2 |
| NCT07096609 | RECRUITING | GIST |
Asan Medical Center |
2025-10-29 | PHASE1; PHASE2 |
| NCT07667751 | RECRUITING | Ovary Cancer |
Bai-Rong Xia |
2026-06-01 | PHASE2 |
| NCT07689201 | NOT_YET_RECRUITING | Gastrointestinal Neoplasms |
GlaxoSmithKline |
2026-08-31 | PHASE2 |
| NCT05734105 | ACTIVE_NOT_RECRUITING | GIST |
Deciphera Pharmaceuticals, LLC |
2023-12-13 | PHASE3 |
| NCT02925234 | RECRUITING | Cancer; Tumors; Neoplasm; Neoplasia |
The Netherlands Cancer Institute |
2016-08 | PHASE2 |
| NCT05905887 | RECRUITING | Gastrointestinal Stromal Tumors |
Asan Medical Center |
2023-09-06 | PHASE2 |
| NCT03900793 | RECRUITING | Osteosarcoma |
University of Colorado, Denver |
2019-08-26 | PHASE1 |
| NCT03541902 | ACTIVE_NOT_RECRUITING | Malignant Neoplasms of Urinary Tract; Renal Cell Carcinoma; Chromophobe Renal Cell Carcinoma; Metastatic Renal Cell Carcinoma; Papillary Renal Cell Carcinoma; Renal Cell Carcinoma Associated With Xp11.2 Translocations/TFE3 Gene Fusions; Sarcomatoid Renal Cell Carcinoma; Stage IV Renal Cell Cancer AJCC v8; Unclassified Renal Cell Carcinoma |
M.D. Anderson Cancer Center |
2018-05-15 | PHASE2 |
| NCT06326346 | RECRUITING | Gastrointestinal Stromal Tumors |
Asan Medical Center |
2024-11-20 | PHASE2 |
| NCT05366816 | RECRUITING | Gastrointestinal Stromal Tumors |
University of Miami |
2023-10-17 | PHASE2 |
| NCT02068586 | ACTIVE_NOT_RECRUITING | Ciliary Body and Choroid Melanoma, Medium/Large Size; Ciliary Body and Choroid Melanoma, Small Size; Iris Melanoma; Stage I Intraocular Melanoma; Stage IIA Intraocular Melanoma; Stage IIB Intraocular Melanoma; Stage IIIA Intraocular Melanoma; Stage IIIB Intraocular Melanoma; Stage IIIC Intraocular Melanoma; Stage I Uveal Melanoma AJCC V7; Stage II Uveal Melanoma AJCC V7; Stage III Uveal Melanoma AJCC V7 |
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University |
2014-11-19 | PHASE2 |
| NCT02465060 | ACTIVE_NOT_RECRUITING | Advanced Lymphoma; Advanced Malignant Solid Neoplasm; Bladder Carcinoma; Breast Carcinoma; Cervical Carcinoma; Colon Carcinoma; Colorectal Carcinoma; Endometrial Carcinoma; Esophageal Carcinoma; Exocrine Pancreas Carcinoma; Gastric Carcinoma; Glioma; Head and Neck Carcinoma; Hematopoietic and Lymphoid Cell Neoplasm; Kidney Carcinoma; Liver Carcinoma; Lung Carcinoma; Lymphoma; Malignant Uterine Corpus Neoplasm; Malignant Uterine Neoplasm; Melanoma; Multiple Myeloma; Ovarian Carcinoma; Prostate Carcinoma; Rectal Carcinoma; Recurrent Bladder Carcinoma; Recurrent Breast Carcinoma; Recurrent Cervical Carcinoma; Recurrent Colon Carcinoma; Recurrent Colorectal Carcinoma; Recurrent Esophageal Carcinoma; Recurrent Gastric Carcinoma; Recurrent Glioma; Recurrent Head and Neck Carcinoma; Recurrent Liver Carcinoma; Recurrent Lung Carcinoma; Recurrent Lymphoma; Recurrent Malignant Solid Neoplasm; Recurrent Malignant Uterine Corpus Neoplasm; Recurrent Melanoma; Recurrent Multiple Myeloma; Recurrent Ovarian Carcinoma; Recurrent Pancreatic Carcinoma; Recurrent Prostate Carcinoma; Recurrent Rectal Carcinoma; Recurrent Skin Carcinoma; Recurrent Thyroid Gland Carcinoma; Refractory Lymphoma; Refractory Malignant Solid Neoplasm; Refractory Multiple Myeloma; Skin Carcinoma; Thyroid Gland Carcinoma |
National Cancer Institute (NCI) |
2015-08-17 | PHASE2 |
| NCT03297606 | RECRUITING | Lymphoma, Non-Hodgkin; Multiple Myeloma; Advanced Solid Tumors |
Canadian Cancer Trials Group |
2018-03-23 | PHASE2 |
| NCT05678673 | ACTIVE_NOT_RECRUITING | Non-Clear Cell Renal Cell Carcinoma |
Exelixis |
2023-01-01 | PHASE3 |
| NCT05687123 | RECRUITING | Metastatic Pancreatic Neuroendocrine Tumor; Pancreatic Neoplasm; Stage III Pancreatic Neuroendocrine Tumor AJCC v8; Stage IV Pancreatic Neuroendocrine Tumor AJCC v8; Unresectable Pancreatic Neuroendocrine Tumor |
National Cancer Institute (NCI) |
2024-08-14 | PHASE1 |
| NCT00715442 | ACTIVE_NOT_RECRUITING | Renal Cell Carcinoma |
M.D. Anderson Cancer Center |
2008-06-24 | PHASE2 |
| NCT05024214 | RECRUITING | Solid Tumors; Non-small Cell Lung Cancer; Renal Cell Carcinoma; Hepatocellular Carcinoma |
3D Medicines (Sichuan) Co., Ltd. |
2021-11-15 | PHASE1; PHASE2 |
| NCT05477576 | RECRUITING | GEP-NET; Gastroenteropancreatic Neuroendocrine Tumor; Gastroenteropancreatic Neuroendocrine Tumor Disease; Neuroendocrine Tumors; Carcinoid; Carcinoid Tumor; Pancreatic NET |
RayzeBio, Inc. |
2022-03-24 | PHASE3 |
| NCT05245968 | ACTIVE_NOT_RECRUITING | Gastrointestinal Stromal Tumors |
Taiho Pharmaceutical Co., Ltd. |
2021-12-01 | PHASE1 |
| NCT03463460 | ACTIVE_NOT_RECRUITING | Thymic Carcinoma |
Dwight Owen |
2018-06-19 | PHASE2 |
| NCT06222593 | RECRUITING | Carcinoma, Renal Cell |
State University of New York at Buffalo |
2024-10-01 | PHASE1; PHASE2 |
| NCT02688491 | UNKNOWN | Renal Neoplasms; Targeted Molecular Therapy |
First Affiliated Hospital, Sun Yat-Sen University |
2016-07 | |
| NCT06208748 | ACTIVE_NOT_RECRUITING | Gastrointestinal Stromal Tumors; GIST |
Sarcoma Alliance for Research through Collaboration |
2024-08-01 | PHASE2 |
| NCT05751733 | RECRUITING | Gastrointestinal Stromal Tumors |
Xiangya Hospital of Central South University |
2023-02-01 | |
| NCT06940349 | RECRUITING | Solid Tumors Refractory to Standard Therapy |
Rabin Medical Center |
2021-10-21 | PHASE1; PHASE2 |
| NCT05043090 | ACTIVE_NOT_RECRUITING | Papillary Renal Cell Carcinoma |
AstraZeneca |
2021-10-28 | PHASE3 |
| NCT05208047 | RECRUITING | Advanced Gastrointestinal Stromal Tumors; Metastatic Cancer |
Cogent Biosciences, Inc. |
2022-04-14 | PHASE3 |
| NCT04523272 | ACTIVE_NOT_RECRUITING | Advanced Renal Cancer |
Chia Tai Tianqing Pharmaceutical Group Co., Ltd. |
2020-08-25 | PHASE3 |
| NCT05949424 | UNKNOWN | Renal Cell Carcinoma; Ovarian Carcinoma; Thyroid Carcinoma; Breast Carcinoma; Endometrium Carcinoma |
University Medical Center Groningen |
2024-05 | PHASE4 |
| NCT03944304 | COMPLETED | Gastrointestinal Stromal Tumors |
Asan Medical Center |
2019-05-27 | PHASE2 |
| NCT04893785 | RECRUITING | Lung Neuroendocrine Neoplasm; GEP Neuroendocrine Tumor |
National Cancer Institute, Naples |
2021-06-15 | PHASE2 |
| NCT03277924 | COMPLETED | Soft Tissue Sarcoma; Bone Sarcoma |
Grupo Espanol de Investigacion en Sarcomas |
2017-05-31 | PHASE1; PHASE2 |
| NCT06222593 | Not yet recruiting | Carcinoma Renal Cell |
State University of New York at Buffalo |
2024-06-01 | Phase 1|Phase 2 |
| NCT04394975 | COMPLETED | Primary Disease: Unresectable or Metastatic Renal Cell Carcinoma Focus of the Study:PFS Assessed by IRC Per RECIST 1.1 |
Shanghai Junshi Bioscience Co., Ltd. |
2020-08-20 | PHASE3 |
| NCT02230176 | COMPLETED | Pancreatic Neuroendocrine Carcinoma |
Gustave Roussy, Cancer Campus, Grand Paris |
2015-02 | PHASE2 |
| NCT06208748 | Not yet recruiting | Gastrointestinal Stromal Tumors|GIST |
Sarcoma Alliance for Research through Collaboration|Cogent Biosciences Inc.|Dana-Farber Cancer Institute|The Life Raft Group |
2024-03 | Phase 2 |
| NCT02689167 | UNKNOWN | Kidney Neoplasms; Metastatic Renal Cell Cancer |
Centre Hospitalier Universitaire de Besancon |
2016-02-19 | PHASE2 |
| NCT04193553 | COMPLETED | Gastro Intestinal Stromal Tumour |
Centre Leon Berard |
2020-01-17 | PHASE2 |
| NCT03013946 | TERMINATED | Renal Cell Carcinoma, Metastatic; Renal Cell Cancer, Recurrent |
AIO-Studien-gGmbH |
2017-01-18 | PHASE3 |
| NCT05816642 | UNKNOWN | Metastatic Renal Cell Carcinoma |
RenJi Hospital |
2022-08-01 | |
| NCT01254864 | COMPLETED | Prostate Cancer |
M.D. Anderson Cancer Center |
2011-03-16 | PHASE2 |
| NCT01391962 | COMPLETED | Sarcoma, Alveolar Soft Part |
National Cancer Institute (NCI) |
2011-07-18 | PHASE2 |
| NCT02761057 | COMPLETED | Locally Advanced Papillary Renal Cell Carcinoma; Metastatic Papillary Renal Cell Carcinoma; Stage III Renal Cell Cancer AJCC v7; Stage IV Renal Cell Cancer AJCC v7; Type 1 Papillary Renal Cell Carcinoma; Type 2 Papillary Renal Cell Carcinoma; Unresectable Renal Cell Carcinoma |
National Cancer Institute (NCI) |
2016-07-25 | PHASE2 |
| NCT02684006 | COMPLETED | Renal Cell Cancer |
Pfizer |
2016-03-23 | PHASE3 |
| NCT00813423 | COMPLETED | Adult Solid Neoplasm |
National Cancer Institute (NCI) |
2010-02-19 | PHASE1 |
| NCT06390826 | ACTIVE_NOT_RECRUITING | Advanced Lymphoma; Advanced Malignant Solid Neoplasm; Refractory Lymphoma; Refractory Malignant Solid Neoplasm; Refractory Multiple Myeloma |
National Cancer Institute (NCI) |
2016-11-01 | PHASE2 |
| NCT05745142 | Completed | Carcinoma Renal Cell|Clear-cell Metastatic Renal Cell Carcinoma |
Pfizer |
2023-02-23 | -- |
| NCT03571438 | UNKNOWN | Kidney Cancer |
University Hospital, Grenoble |
2017-10-16 | |
| NCT04006769 | COMPLETED | Gastrointestinal Stromal Tumor, Malignant |
Xiangya Hospital of Central South University |
2020-10-30 | EARLY_PHASE1 |
| NCT04633122 | COMPLETED | Gastrointestinal Stromal Tumor(GIST) |
Zai Lab (Shanghai) Co., Ltd. |
2020-11-25 | PHASE2 |
| NCT03449173 | UNKNOWN | Type B3 Thymoma; Thymic Carcinoma |
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano |
2017-03-02 | PHASE2 |
| NCT04409223 | TERMINATED | Gastrointestinal Stromal Tumors |
Jiangsu HengRui Medicine Co., Ltd. |
2020-09-12 | PHASE3 |
| NCT00843037 | COMPLETED | Paraganglioma; Pheochromocytoma |
University Health Network, Toronto |
2009-02 | PHASE2 |
| NCT03905889 | TERMINATED | Renal Cell Carcinoma Metastatic |
Brown University |
2019-06-05 | PHASE1 |
| NCT03729245 | TERMINATED | Renal Cell Carcinoma; Metastatic Renal Cell Carcinoma |
Nektar Therapeutics |
2018-12-18 | PHASE3 |
| NCT03025893 | UNKNOWN | Glioblastoma Multiforme; Glioblastoma, Adult; Glioblastoma; Recurrent Brain Tumor; GBM |
Amsterdam UMC, location VUmc |
2018-08-31 | PHASE2; PHASE3 |
| NCT03609424 | COMPLETED | Gastrointestinal Stromal Tumors |
Asan Medical Center |
2019-02-14 | PHASE1; PHASE2 |
| NCT02239952 | UNKNOWN | Cancer; High-grade Glioma |
Amsterdam UMC, location VUmc |
2014-11 | |
| NCT03170180 | COMPLETED | Stomach Neoplasms |
Samsung Medical Center |
2017-03-01 | PHASE2 |
| NCT05043090 | Recruiting | Papillary Renal Cell Carcinoma |
AstraZeneca |
2021-10-28 | Phase 3 |
| NCT03673501 | ACTIVE_NOT_RECRUITING | Gastrointestinal Stromal Tumors |
Deciphera Pharmaceuticals, LLC |
2019-02-08 | PHASE3 |
| NCT03909724 | UNKNOWN | Colorectal Cancer; Metastasis |
Amsterdam UMC, location VUmc |
2019-10-01 | PHASE2; PHASE3 |
| NCT03862768 | UNKNOWN | Gastrointestinal Stromal Tumors; Surgery |
Shanghai Zhongshan Hospital |
2019-07 | |
| NCT01621568 | COMPLETED | Thymoma; Thymus Neoplasms |
National Cancer Institute (NCI) |
2012-05-15 | PHASE2 |
| NCT03641326 | TERMINATED | Gliosarcoma; Central Nervous System Sarcoma |
National Cancer Institute (NCI) |
2019-02-21 | PHASE2 |
| NCT02019576 | COMPLETED | Clear Cell Metastatic Renal Cell Carcinoma |
Sunnybrook Health Sciences Centre |
2014-05 | PHASE2 |
| NCT02960906 | COMPLETED | Clear Cell Metastatic Renal Cell Carcinoma |
Association Pour La Recherche des Thérapeutiques Innovantes en Cancérologie |
2017-05-31 | PHASE2 |
| NCT02432846 | COMPLETED | Renal Cell Carcinoma, Metastatic |
Mendus |
2015-04 | PHASE2 |
| NCT04669366 | Completed | Kidney Neoplasms |
Pfizer |
2021-01-20 | -- |
| NCT03953079 | COMPLETED | Neovascular Age-Related Macular Degeneration |
Graybug Vision |
2019-09-26 | PHASE2 |
| NCT03878524 | TERMINATED | Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Anatomic Stage IV Breast Cancer AJCC v8; Anemia; Ann Arbor Stage III Hodgkin Lymphoma; Ann Arbor Stage III Non-Hodgkin Lymphoma; Ann Arbor Stage IV Hodgkin Lymphoma; Ann Arbor Stage IV Non-Hodgkin Lymphoma; Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative; Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Castration-Resistant Prostate Carcinoma; Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Hematopoietic and Lymphoid System Neoplasm; Locally Advanced Pancreatic Adenocarcinoma; Metastatic Breast Carcinoma; Metastatic Malignant Solid Neoplasm; Metastatic Pancreatic Adenocarcinoma; Myelodysplastic/Myeloproliferative Neoplasm With Ring Sideroblasts and Thrombocytosis; Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable; Primary Myelofibrosis; Recurrent Acute Lymphoblastic Leukemia; Recurrent Acute Myeloid Leukemia; Recurrent Chronic Lymphocytic Leukemia; Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Recurrent Hematologic Malignancy; Recurrent Hodgkin Lymphoma; Recurrent Myelodysplastic Syndrome; Recurrent Myelodysplastic/Myeloproliferative Neoplasm; Recurrent Myeloproliferative Neoplasm; Recurrent Non-Hodgkin Lymphoma; Recurrent Plasma Cell Myeloma; Recurrent Small Lymphocytic Lymphoma; Refractory Acute Lymphoblastic Leukemia; Refractory Acute Myeloid Leukemia; Refractory Chronic Lymphocytic Leukemia; Refractory Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Refractory Chronic Myelomonocytic Leukemia; Refractory Hematologic Malignancy; Refractory Hodgkin Lymphoma; Refractory Malignant Solid Neoplasm; Refractory Myelodysplastic Syndrome; Refractory Myelodysplastic/Myeloproliferative Neoplasm; Refractory Non-Hodgkin Lymphoma; Refractory Plasma Cell Myeloma; Refractory Primary Myelofibrosis; Refractory Small Lymphocytic Lymphoma; Stage II Pancreatic Cancer AJCC v8; Stage III Pancreatic Cancer AJCC v8; Stage IV Pancreatic Cancer AJCC v8; Stage IV Prostate Cancer AJCC v8; Unresectable Pancreatic Adenocarcinoma |
OHSU Knight Cancer Institute |
2020-04-01 | PHASE1 |
| NCT01664182 | COMPLETED | Advanced Renal Cell Carcinoma; Advanced Sarcomatoid Renal Cell Carcinoma; Stage III Renal Cell Cancer AJCC v7; Stage IV Renal Cell Cancer AJCC v7 |
National Cancer Institute (NCI) |
2012-08-01 | PHASE2 |
| NCT01694277 | COMPLETED | Gastrointestinal Stromal Tumors |
AB Science |
2012-04 | PHASE3 |
| NCT02919371 | UNKNOWN | Renal Cell Carcinoma |
King Faisal Specialist Hospital & Research Center |
2014-12 | PHASE1; PHASE2 |
| NCT03066427 | COMPLETED | Clear Cell Renal Carcinoma |
Spanish Oncology Genito-Urinary Group |
2017-05-10 | PHASE2 |
| NCT02811861 | ACTIVE_NOT_RECRUITING | Renal Cell Carcinoma |
Eisai Inc. |
2016-10-13 | PHASE3 |
| NCT02959554 | TERMINATED | Metastatic Renal Cell Carcinoma |
AIO-Studien-gGmbH |
2016-12 | PHASE2 |
| NCT04085341 | COMPLETED | Diabetic Macular Edema; Retina Vein Occlusion |
Graybug Vision |
2019-09-11 | PHASE2 |
| NCT02401815 | COMPLETED | Gastrointestinal Stromal Tumors |
Cogent Biosciences, Inc. |
2015-03-06 | PHASE1; PHASE2 |
| NCT02790580 | UNKNOWN | Breast Cancer |
National University Hospital, Singapore |
2016-05 | PHASE2 |
| NCT00543504 | COMPLETED | Advanced Cancer |
M.D. Anderson Cancer Center |
2007-10-10 | PHASE1 |
| NCT01566747 | COMPLETED | Renal Cell Carcinoma |
Cancer Trials Ireland |
2011-03 | PHASE2 |
| NCT01164228 | COMPLETED | Kidney Cancer |
ECOG-ACRIN Cancer Research Group |
2010-09-17 | PHASE2 |
| NCT02420821 | COMPLETED | Renal Cell Carcinoma |
Hoffmann-La Roche |
2015-05-20 | PHASE3 |
| NCT03141177 | COMPLETED | Renal Cell Carcinoma |
Bristol-Myers Squibb |
2017-07-23 | PHASE3 |
| NCT02555748 | COMPLETED | Metastatic Renal Cell Cancer |
Institut Claudius Regaud |
2015-11-17 | PHASE4 |
| NCT02342600 | WITHDRAWN | Gastrointestinal Stromal Tumors |
Sarcoma Alliance for Research through Collaboration |
2017-01 | PHASE2 |
| NCT03592199 | UNKNOWN | Clear Cell Renal Cell Carcinoma |
Instituto do Cancer do Estado de São Paulo |
2017-12-11 | PHASE2 |
| NCT03323710 | WITHDRAWN | Renal Cell Carcinoma |
Military Institute od Medicine National Research Institute |
2018-09 | PHASE2 |
| NCT02713763 | COMPLETED | Pancreatic Neuroendocrine Tumour Metastatic |
Grupo Espanol de Tumores Neuroendocrinos |
2017-02-14 | PHASE2 |
| NCT03109015 | COMPLETED | Carcinoma, Renal Cell |
Duke University |
2017-09-27 | PHASE2 |
| NCT01185366 | TERMINATED | Kidney Cancer |
M.D. Anderson Cancer Center |
2010-08 | PHASE2 |
| NCT02450123 | COMPLETED | Refractory Solid Tumors |
Samsung Medical Center |
2016-03-23 | |
| NCT02691793 | COMPLETED | Refractory Solid Tumors |
Samsung Medical Center |
2017-11-20 | PHASE4 |
| NCT03091192 | ACTIVE_NOT_RECRUITING | Carcinoma; Carcinoma, Renal Cell; Kidney Neoplasms; Urologic Neoplasms; Kidney Diseases; Neoplasms by Site; Enzyme Inhibitors; Protein Kinase Inhibitors |
AstraZeneca |
2017-07-25 | PHASE3 |
| NCT02058901 | COMPLETED | Solid Tumors |
Amsterdam UMC, location VUmc |
2013-07 | PHASE1 |
| NCT02315625 | TERMINATED | Neuroendocrine Tumors; Neuroendocrine Carcinoma; Neuroendocrine Neoplasms; Carcinoma, Neuroendocrine; Neuroendocrine Tumors of the Gastrointestinal Tract and Pancreas |
National Cancer Institute (NCI) |
2015-04-08 | PHASE2 |
| NCT02216578 | COMPLETED | Metastatic Gastrointestinal Stromal Tumor |
European Organisation for Research and Treatment of Cancer - EORTC |
2017-02-02 | PHASE2 |
| NCT02483247 | COMPLETED | Cancer |
Sumitomo Pharma America, Inc. |
2015-09 | PHASE1 |
| NCT01309633 | COMPLETED | Nasopharyngeal Carcinoma |
National University Hospital, Singapore |
2011-09-02 | PHASE2 |
| NCT00478426 | COMPLETED | Endometrial Adenocarcinoma; Endometrial Endometrioid Adenocarcinoma; Endometrial Serous Adenocarcinoma; Recurrent Uterine Corpus Carcinoma; Stage IVA Uterine Corpus Cancer AJCC v7; Stage IVB Uterine Corpus Cancer AJCC v7; Uterine Carcinosarcoma; Uterine Corpus Carcinosarcoma |
National Cancer Institute (NCI) |
2007-04-30 | PHASE2 |
| NCT05800106 | COMPLETED | Gastrointestinal Stromal Tumors; Renal Cell Carcinoma; Pancreatic Neuroendocrine Tumor |
Chia Tai Tianqing Pharmaceutical Group Co., Ltd. |
2018-12-04 | PHASE1 |
| NCT02060370 | COMPLETED | Genitourinary Cancer; Kidney Cancer |
M.D. Anderson Cancer Center |
2014-08 | PHASE2 |
| NCT02570789 | TERMINATED | Clear-cell Metastatic Renal Cell Carcinoma |
Cliniques universitaires Saint-Luc- Université Catholique de Louvain |
2012-12 | PHASE4 |
| NCT03035630 | WITHDRAWN | Clear-cell Renal Cell Carcinoma; RCC; Kidney Cancer; Clear-cell Kidney Carcinoma |
Guru Sonpavde |
2017-05-23 | PHASE2 |
| NCT00930033 | COMPLETED | Metastatic Renal Cell Carcinoma |
Assistance Publique - Hôpitaux de Paris |
2009-09-09 | PHASE3 |
| NCT01735968 | COMPLETED | 3rd Line GIST |
Novartis Pharmaceuticals |
2013-02-27 | PHASE1 |
| NCT02853331 | COMPLETED | Renal Cell Carcinoma |
Merck Sharp & Dohme LLC |
2016-09-16 | PHASE3 |
| NCT02535351 | TERMINATED | Clear-cell Metastatic Renal Cell Carcinoma |
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano |
2015-11 | PHASE3 |
| NCT03249740 | COMPLETED | Neovascular Age-Related Macular Degeneration |
Graybug Vision |
2017-08-29 | PHASE1 |
| NCT03260894 | COMPLETED | Renal Cell Carcinoma (RCC) |
Incyte Corporation |
2017-12-07 | PHASE3 |
| NCT01517243 | COMPLETED | Metastatic Renal Cell Carcinoma |
Dartmouth-Hitchcock Medical Center |
2010-09-22 | PHASE2 |
| NCT03275558 | WITHDRAWN | Recurrent Glioblastoma; Gliosarcoma; Anaplastic Gliomas |
Center Trials & Treatment |
2018-07-17 | PHASE1 |
| NCT02402062 | COMPLETED | Neuroendocrine Tumors; Pancreatic Neoplasms |
Grupo Espanol de Tumores Neuroendocrinos |
2015-05-11 | PHASE2 |
| NCT02779283 | COMPLETED | Acute Lymphoblastic Leukemia; Acute Myeloid Leukemia |
OHSU Knight Cancer Institute |
2016-01-13 | PHASE1 |
| NCT02208128 | UNKNOWN | Renal Cell Carcinoma |
Heidelberg University |
2014-05 | |
| NCT03379012 | COMPLETED | Metastatic Renal Cell Carcinoma |
Kidney Cancer Research Bureau |
2016-02-08 | PHASE2 |
| NCT01005472 | COMPLETED | Metastatic Melanoma |
Jonsson Comprehensive Cancer Center |
2008-12-01 | PHASE1 |
| NCT02626754 | TERMINATED | Renal Cell Carcinoma |
vghtpe user |
2015-08-12 | PHASE2 |
| NCT01636908 | COMPLETED | Cancer; Advanced Solid Tumors |
Amsterdam UMC, location VUmc |
2011-08 | |
| NCT02607332 | COMPLETED | Gastrointestinal Stromal Tumors |
Asan Medical Center |
2015-11 | PHASE2 |
| NCT01190241 | TERMINATED | Advanced Solid Tumors; Inoperable; Metastasis |
Amsterdam UMC, location VUmc |
2010-08 | |
| NCT02446795 | UNKNOWN | Renal Cell Carcinoma; Kidney Cancer |
Consorzio Oncotech |
2016-11 | PHASE1; PHASE2 |
| NCT02623127 | COMPLETED | Thymic Carcinoma |
Seoul National University Hospital |
2015-10 | PHASE2 |
| NCT01731925 | UNKNOWN | Carcinoid Tumors |
GERCOR - Multidisciplinary Oncology Cooperative Group |
2013-01-07 | PHASE2 |
| NCT03456401 | TERMINATED | Renal Cancer Cell |
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano |
2014-11 | PHASE2 |
| NCT01499121 | COMPLETED | Clear Cell, Metastatic Renal Cell Carcinoma |
Sunnybrook Health Sciences Centre |
2012-05 | PHASE2 |
| NCT01551459 | COMPLETED | Metastatic Uveal Melanoma |
The Clatterbridge Cancer Centre NHS Foundation Trust |
2010-10 | PHASE2 |
| NCT02889328 | COMPLETED | Gastrointestinal Stromal Tumors (GISTs) |
Asan Medical Center |
2016-09 | PHASE2 |
| NCT01396148 | COMPLETED | Gastrointestinal Stromal Tumors |
Pfizer |
2012-06 | PHASE2 |
| NCT01829217 | COMPLETED | Lung Cancer |
Dana-Farber Cancer Institute |
2013-05 | PHASE2 |
| NCT02386111 | TERMINATED | Carcinoma, Renal Cell; Kidney Diseases; Kidney Neoplasms; Urogenital Neoplasms; Urologic Diseases; Urologic Neoplasms; Neoplasms; Neoplasms by Histologic Type; Clear-cell Metastatic Renal Cell Carcinoma |
Celldex Therapeutics |
2015-05 | PHASE1 |
| NCT02560012 | TERMINATED | Carcinoma, Renal Cell |
The University of Texas Health Science Center, Houston |
2016-01-04 | PHASE2 |
| NCT01164202 | COMPLETED | Liver Cancer |
Federation Francophone de Cancerologie Digestive |
2010-07 | PHASE2; PHASE3 |
| NCT02231749 | COMPLETED | Advanced Renal Cell Carcinoma; Metastatic Renal Cell Carcinoma |
Bristol-Myers Squibb |
2014-10-16 | PHASE3 |
| NCT02074878 | TERMINATED | Breast Cancer |
Mothaffar Rimawi |
2014-06 | PHASE1 |
| NCT01784978 | TERMINATED | Metastatic Renal Cell Carcinoma |
Associació per a la Recerca Oncologica, Spain |
2013-02-12 | PHASE2 |
| NCT02013089 | UNKNOWN | Gastrointestinal Cancers |
Sun Yat-sen University |
2013-12 | |
| NCT01620216 | TERMINATED | Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome; Chronic Myelomonocytic Leukemia; Recurrent Acute Lymphoblastic Leukemia; Recurrent Acute Myeloid Leukemia; Refractory Acute Lymphoblastic Leukemia; Refractory Acute Myeloid Leukemia |
OHSU Knight Cancer Institute |
2012-05-11 | PHASE2 |
| NCT01803503 | UNKNOWN | Solid Tumors; Breast Cancer; Non-small Cell Lung Cancer; Prostate Cancer; Gastric Cancer |
National University Hospital, Singapore |
2013-05 | PHASE2 |
| NCT02398552 | UNKNOWN | Metastatic Renal Cell Carcinoma |
Peking University Cancer Hospital & Institute |
2015-03 | PHASE2 |
| NCT00381641 | COMPLETED | Differentiated Thyroid Gland Carcinoma; Recurrent Thyroid Gland Carcinoma; Refractory Thyroid Gland Carcinoma; Stage III Thyroid Gland Follicular Carcinoma AJCC v7; Stage III Thyroid Gland Medullary Carcinoma AJCC v7; Stage IV Thyroid Gland Follicular Carcinoma AJCC v7; Stage IV Thyroid Gland Medullary Carcinoma AJCC v7; Stage IV Thyroid Gland Papillary Carcinoma AJCC v7; Stage IVA Thyroid Gland Follicular Carcinoma AJCC v7; Stage IVA Thyroid Gland Medullary Carcinoma AJCC v7; Stage IVA Thyroid Gland Papillary Carcinoma AJCC v7; Stage IVB Thyroid Gland Follicular Carcinoma AJCC v7; Stage IVB Thyroid Gland Medullary Carcinoma AJCC v7; Stage IVB Thyroid Gland Papillary Carcinoma AJCC v7; Stage IVC Thyroid Gland Follicular Carcinoma AJCC v7; Stage IVC Thyroid Gland Medullary Carcinoma AJCC v7; Stage IVC Thyroid Gland Papillary Carcinoma AJCC v7; Thyroid Gland Oncocytic Carcinoma; Unresectable Thyroid Gland Carcinoma |
National Cancer Institute (NCI) |
2006-08-29 | PHASE2 |
| NCT02164240 | COMPLETED | Gastrointestinal Stromal Tumor |
Dana-Farber Cancer Institute |
2014-07 | PHASE1 |
| NCT02928575 | UNKNOWN | Glioblastoma Multiforme |
Bassam Abdulkarim |
2012-08 | PHASE2 |
| NCT01176799 | UNKNOWN | Breast Cancer |
National University Hospital, Singapore |
2010-08 | PHASE2 |
| NCT02072031 | UNKNOWN | Anlotinib; RCC |
Chia Tai Tianqing Pharmaceutical Group Co., Ltd. |
2013-12 | PHASE2 |
| NCT01907607 | COMPLETED | Advanced Gastrointestinal Stromal Tumors |
Institut Bergonié |
2014-02 | PHASE2 |
| NCT01718327 | COMPLETED | Unresectable and Advanced Cholangiocarcinoma |
GERCOR - Multidisciplinary Oncology Cooperative Group |
2011-09-01 | PHASE2 |
| NCT01984242 | COMPLETED | Renal Cell Carcinoma |
Hoffmann-La Roche |
2014-01-08 | PHASE2 |
| NCT00400114 | COMPLETED | Esophageal Cancer |
University Health Network, Toronto |
2006-09-25 | PHASE2 |
| NCT02071641 | TERMINATED | Metastatic Renal Cell Carcinoma |
Amsterdam UMC, location VUmc |
2012-10 | PHASE2 |
| NCT00794950 | COMPLETED | Urinary Tract Urothelial Carcinoma |
University of Michigan |
2009-01 | PHASE2 |
| NCT02268435 | WITHDRAWN | Gastrointestinal Stromal Tumors |
Asan Medical Center |
2015-03 | PHASE1 |
| NCT01468688 | COMPLETED | 3rd Line GIST |
Novartis Pharmaceuticals |
2012-04-20 | PHASE1 |
| NCT01308034 | COMPLETED | Non GIST Sarcomas |
Centre Leon Berard |
2011-03 | PHASE1 |
| NCT01835158 | COMPLETED | Clear Cell Renal Cell Carcinoma; Metastatic Kidney Carcinoma; Stage III Renal Cell Cancer AJCC v7; Stage IV Renal Cell Cancer AJCC v7 |
National Cancer Institute (NCI) |
2013-07-08 | PHASE2 |
| NCT00375674 | COMPLETED | Kidney Neoplasms |
Pfizer |
2007-08-01 | PHASE3 |
| NCT01514448 | COMPLETED | Metastatic Renal Cell Carcinoma (mRCC) |
Novartis Pharmaceuticals |
2012-05-21 | PHASE4 |
| NCT01525550 | COMPLETED | Well-differentiated Pancreatic Neuroendocrine Tumor |
Pfizer |
2012-06-06 | PHASE4 |
| NCT01472081 | COMPLETED | Renal Cell Carcinoma; Clear-cell Metastatic Renal Cell Carcinoma |
Bristol-Myers Squibb |
2012-02-09 | PHASE1 |
| NCT02380625 | UNKNOWN | Ebola Virus Disease |
Clinical Research Management, Inc. |
2015-04 | PHASE1; PHASE2 |
| NCT01824615 | COMPLETED | Ovarian Cancer; Adverse Effects |
Cathay General Hospital |
2013-01 | PHASE2 |
| NCT02400385 | WITHDRAWN | Melanoma |
California Pacific Medical Center Research Institute |
2014-10 | PHASE2 |
| NCT02324803 | UNKNOWN | Self Efficacy; Adverse Drug Event; Carcinoma, Renal Cell |
Southern China Urology Cancer Consortium |
2014-07 | PHASE2 |
| NCT01061411 | COMPLETED | Clear Cell Sarcoma of the Kidney; Recurrent Renal Cell Carcinoma; Stage III Renal Cell Cancer; Stage IV Renal Cell Cancer |
Roswell Park Cancer Institute |
2010-02-06 | PHASE1 |
| NCT01216371 | TERMINATED | Renal Cell Carcinoma; Pulmonary Metastases |
Association of Urologic Oncology (AUO) |
2010-10 | PHASE2 |
| NCT01402817 | TERMINATED | Neurofibromatosis; NF1; Plexiform Neurofibromas |
Indiana University |
2012-03 | PHASE2 |
| NCT00326898 | COMPLETED | Clear Cell Renal Cell Carcinoma; Stage I Renal Cell Cancer AJCC v6 and v7; Stage II Renal Cell Cancer AJCC v7; Stage III Renal Cell Cancer AJCC v7 |
National Cancer Institute (NCI) |
2006-04-24 | PHASE3 |
| NCT01396408 | ACTIVE_NOT_RECRUITING | Advanced Rare Tumours |
Canadian Cancer Trials Group |
2012-02-09 | PHASE2 |
| NCT01265901 | COMPLETED | Metastatic Renal Cell Carcinoma |
Immatics Biotechnologies GmbH |
2010-12 | PHASE3 |
| NCT01402089 | COMPLETED | Non Small-cell Lung Cancer; Renal-cell Cancer; Gastrointestinal Stroma Tumor |
Markus Joerger |
2012-01 | PHASE4 |
| NCT01389583 | UNKNOWN | Gastrointestinal Stromal Tumor |
National Health Research Institutes, Taiwan |
2011-10 | PHASE2 |
| NCT00519896 | COMPLETED | Recurrent Thyroid Cancer; Stage IVA Follicular Thyroid Cancer; Stage IVA Papillary Thyroid Cancer; Stage IVB Follicular Thyroid Cancer; Stage IVB Papillary Thyroid Cancer; Stage IVC Follicular Thyroid Cancer; Stage IVC Papillary Thyroid Cancer; Thyroid Gland Medullary Carcinoma |
University of Washington |
2007-07 | PHASE2 |
| NCT00903175 | COMPLETED | Renal Cell Carcinoma |
Novartis Pharmaceuticals |
2009-10 | PHASE2 |
| NCT00465179 | COMPLETED | Renal Cell Cancer; Kidney Cancer |
M.D. Anderson Cancer Center |
2007-03 | PHASE2 |
| NCT01108445 | COMPLETED | Advanced Non-clear Cell Renal Cell Carcinoma |
Duke University |
2010-09 | PHASE2 |
| NCT01524848 | COMPLETED | Gastrointestinal Stromal Tumors |
Scandinavian Sarcoma Group |
2012-02 | PHASE2 |
| NCT00631527 | COMPLETED | Prostate Cancer |
M.D. Anderson Cancer Center |
2008-02 | PHASE1 |
| NCT00912912 | TERMINATED | Genitourinary Disease |
M.D. Anderson Cancer Center |
2009-05 | PHASE2 |
| NCT01034878 | COMPLETED | Carcinoma, Renal Cell |
Istituto Clinico Humanitas |
2009-12 | PHASE2 |
| NCT00943839 | COMPLETED | Kidney Cancer |
Centre Antoine Lacassagne |
2009-02 | |
| NCT01498835 | COMPLETED | Soft Tissue Sarcoma |
Heidelberg University |
2012-02 | PHASE1 |
| NCT01089088 | COMPLETED | Bladder Cancer; Transitional Cell Cancer of the Renal Pelvis and Ureter; Urethral Cancer |
Cardiff University |
2009-04 | PHASE2 |
| NCT00589784 | COMPLETED | CNS Cancer; Meningioma; Intracranial Hemangiopericytoma; Hemangioblastoma; Neurofibromatosis |
Memorial Sloan Kettering Cancer Center |
2007-10 | PHASE2 |
| NCT01850147 | UNKNOWN | Cancer; Lung Cancer |
Chinese Academy of Medical Sciences |
2013-03 | PHASE2 |
| NCT00694096 | COMPLETED | Renal Cell Cancer |
University of Utah |
2007-09 | PHASE1 |
| NCT00734851 | TERMINATED | Prostate Cancer |
Duke University |
2008-12 | PHASE2 |
| NCT01391130 | TERMINATED | Metastatic Clear Cell Renal Cell Carcinoma |
Eli Lilly and Company |
2011-08 | PHASE2 |
| NCT01054911 | TERMINATED | Tumor |
University of Alabama at Birmingham |
2009-10 | |
| NCT00577382 | COMPLETED | Mucosal Lentiginous Melanoma; Acral Lentiginous Malignant Melanoma |
Dana-Farber Cancer Institute |
2007-08 | PHASE2 |
| NCT00428220 | COMPLETED | Metastatic Breast Cancer; Advanced Breast Cancer; Metastatic Castration Resistant Prostate Cancer; Metastatic Renal Cell Cancer; Non-Small Cell Lung Cancer; Thyroid Cancer; Advanced/Metastatic Non-Small Cell Lung Cancer; Advanced Gastric Cancer; Gastrointestinal Stromal Tumor; Hepatocellular Carcinoma; Pancreatic Islet Cell Carcinoma; Pancreatic Neuroendocrine Tumor |
Pfizer |
2007-07 | |
| NCT01122615 | COMPLETED | Renal Cell Cancer; Kidney Cancer |
M.D. Anderson Cancer Center |
2010-05 | PHASE1 |
| NCT01289028 | COMPLETED | Gastrointestinal Stromal Tumors |
Novartis Pharmaceuticals |
2008-11 | PHASE3 |
| NCT00463060 | COMPLETED | Cancer |
Icahn School of Medicine at Mount Sinai |
2007-01 | PHASE1; PHASE2 |
| NCT00747305 | TERMINATED | Kidney Cancer |
Harry Drabkin |
2008-10 | PHASE1 |
| NCT01381822 | UNKNOWN | Advanced Renal Cell Carcinoma; Gastrointestinal Stromal Tumors; Pancreatic Neuroendocrine Tumors |
Threshold Pharmaceuticals |
2011-06 | PHASE1 |
| NCT00570882 | COMPLETED | Metastatic Renal Cell Carcinoma |
Asan Medical Center |
2007-10 | PHASE2 |
| NCT00499135 | COMPLETED | Adult Solid Neoplasm; Clear Cell Renal Cell Carcinoma; Recurrent Renal Cell Carcinoma; Stage III Renal Cell Cancer; Stage IV Renal Cell Cancer |
National Cancer Institute (NCI) |
2007-05-22 | PHASE1 |
| NCT00979992 | COMPLETED | Ovarian Clear Cell Adenocarcinoma; Recurrent Ovarian Carcinoma |
National Cancer Institute (NCI) |
2010-04-19 | PHASE2 |
| NCT00981890 | COMPLETED | Brain Metastases |
University Health Network, Toronto |
2009-07 | PHASE1 |
| NCT00793871 | COMPLETED | Gastrointestinal Neoplasms, Gastrointestinal Stromal Tumors |
Pfizer |
2008-11 | PHASE4 |
| NCT01323400 | COMPLETED | GIST |
Centre Leon Berard |
2011-03 | PHASE2 |
| NCT01740154 | TERMINATED | Fatigue; Recurrent Renal Cell Cancer; Stage IV Renal Cell Cancer |
Case Comprehensive Cancer Center |
2012-09 | |
| NCT00982657 | TERMINATED | Solid Tumor |
Pfizer |
2009-09 | PHASE2 |
| NCT00853125 | TERMINATED | Kidney Cancer |
Rutgers, The State University of New Jersey |
2009-02 | PHASE2 |
| NCT01306045 | COMPLETED | Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell Lung; Carcinoma, Thymic |
National Cancer Institute (NCI) |
2011-02-08 | PHASE2 |
| NCT01502228 | TERMINATED | Renal Cell Carcinoma |
Indiana University |
2011-10 | |
| NCT01243359 | COMPLETED | Clear Cell Renal Cell Carcinoma; Recurrent Renal Cell Cancer; Stage I Renal Cell Cancer; Stage II Renal Cell Cancer; Stage III Renal Cell Cancer; Stage IV Renal Cell Cancer; Unspecified Adult Solid Tumor, Protocol Specific |
National Cancer Institute (NCI) |
2010-10 | PHASE1 |
| NCT01673386 | TERMINATED | Metastatic Renal Cell Carcinoma |
AVEO Pharmaceuticals, Inc. |
2012-07 | PHASE2 |
| NCT00556049 | COMPLETED | Renal Cell Carcinoma; Neoplasm Metastases |
Massachusetts General Hospital |
2007-12 | PHASE2 |
| NCT01462695 | COMPLETED | Childhood Cerebellar Anaplastic Astrocytoma; Childhood Cerebral Anaplastic Astrocytoma; Childhood Cerebral Astrocytoma; Childhood Infratentorial Ependymoma; Childhood Mixed Glioma; Childhood Oligodendroglioma; Childhood Supratentorial Ependymoma; Recurrent Childhood Cerebellar Astrocytoma; Recurrent Childhood Cerebral Astrocytoma; Recurrent Childhood Ependymoma; Recurrent Childhood Subependymal Giant Cell Astrocytoma |
National Cancer Institute (NCI) |
2012-01 | PHASE2 |
| NCT01215578 | TERMINATED | Neuroendocrine Tumors; Pancreatic Neoplasms; Advanced Disease; Sunitinib |
Assistance Publique - Hôpitaux de Paris |
2008-10 | PHASE2 |
| NCT00693992 | COMPLETED | Stage IIIB Lung Non-Small Cell Cancer AJCC v7; Stage IV Non-Small Cell Lung Cancer AJCC v7 |
National Cancer Institute (NCI) |
2008-06-15 | PHASE3 |
| NCT01441388 | WITHDRAWN | Carcinoma, Renal Cell; Glioblastoma; Carcinoma, Hepatocellular |
Pfizer |
2011-12 | PHASE1 |
| NCT00884676 | COMPLETED | Unspecified Adult Solid Tumor, Protocol Specific |
Jaime Merchan |
2008-11 | PHASE1 |
| NCT01371201 | COMPLETED | Malignant Progressive Pheochromocytoma and Paraganglioma (PPGL) |
Gustave Roussy, Cancer Campus, Grand Paris |
2011-12-22 | PHASE2 |
| NCT00732914 | COMPLETED | Renal Cell Carcinoma |
Sponsor GmbH |
2009-01 | PHASE3 |
| NCT00702884 | COMPLETED | Esophageal Cancer |
Tony Bekaii-Saab |
2008-06-30 | PHASE2 |
| NCT00570908 | TERMINATED | Breast Cancer |
Baylor Breast Care Center |
2009-02 | PHASE2 |
| NCT00524186 | TERMINATED | Esophageal Cancer; Gastric Cancer |
Roswell Park Cancer Institute |
2007-05 | PHASE1 |
| NCT01481870 | UNKNOWN | Metastatic Renal Cell Carcinoma |
Yamagata University |
2010-01 | PHASE3 |
| NCT00887575 | COMPLETED | Breast Cancer |
SCRI Development Innovations, LLC |
2009-06 | PHASE1; PHASE2 |
| NCT00783653 | COMPLETED | Acute Myeloid Leukemia |
Universitätsklinikum Hamburg-Eppendorf |
2008-08 | PHASE1; PHASE2 |
| NCT00718562 | COMPLETED | Gastrointestinal Stromal Tumors |
Novartis Pharmaceuticals |
2008-09 | PHASE2 |
| NCT00453154 | COMPLETED | Extensive Stage Lung Small Cell Carcinoma; Recurrent Lung Small Cell Carcinoma |
National Cancer Institute (NCI) |
2007-03-15 | PHASE1; PHASE2 |
| NCT01158222 | COMPLETED | Clear Cell Renal Cell Carcinoma; Stage IV Renal Cell Cancer |
Case Comprehensive Cancer Center |
2010-08-18 | PHASE2 |
| NCT01216657 | TERMINATED | Chemo-refractory Melanoma |
Krankenhaus Nordwest |
2009-03 | PHASE2 |
| NCT01829841 | COMPLETED | Renal Cell Cancer; Metastatic Renal Cell Cancer |
Jiangsu HengRui Medicine Co., Ltd. |
2011-05 | PHASE2 |
| NCT01440959 | COMPLETED | Gastrointestinal Stromal Tumors |
Asan Medical Center |
2011-09 | PHASE2 |
| NCT01151852 | COMPLETED | Gastrointestinal Stromal Tumors |
Asan Medical Center |
2010-06 | PHASE3 |
| NCT00891878 | COMPLETED | Adenocarcinoma of the Gastroesophageal Junction; Esophageal Cancer |
Alliance for Clinical Trials in Oncology |
2009-08 | PHASE2 |
| NCT00886132 | COMPLETED | Adenoid Cystic Carcinoma; Salivary Gland Cancer |
University Health Network, Toronto |
2007-01 | PHASE2 |
| NCT00788060 | COMPLETED | Renal Cell Carcinoma |
Daniel George, MD |
2008-10 | PHASE1 |
| NCT00489944 | UNKNOWN | Intraocular Melanoma |
San Diego Pacific Oncology & Hematology Associates |
2007-05 | PHASE2 |
| NCT00859456 | TERMINATED | Sarcoma, Soft Tissue |
Columbia University |
2007-04 | PHASE2 |
| NCT01020630 | COMPLETED | Adenocarcinoma |
PD Dr Markus Möhler |
2009-11 | PHASE2 |
| NCT00847015 | COMPLETED | Bladder Cancer; Urinary Bladder |
Memorial Sloan Kettering Cancer Center |
2009-02 | PHASE2 |
| NCT00495872 | COMPLETED | Solid Tumors |
M.D. Anderson Cancer Center |
2007-06 | PHASE1 |
| NCT00906360 | TERMINATED | Metastatic Squamous Neck Cancer With Occult Primary Squamous Cell Carcinoma; Recurrent Metastatic Squamous Neck Cancer With Occult Primary; Recurrent Salivary Gland Cancer; Recurrent Squamous Cell Carcinoma of the Hypopharynx; Recurrent Squamous Cell Carcinoma of the Larynx; Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity; Recurrent Squamous Cell Carcinoma of the Nasopharynx; Recurrent Squamous Cell Carcinoma of the Oropharynx; Recurrent Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity; Recurrent Verrucous Carcinoma of the Larynx; Recurrent Verrucous Carcinoma of the Oral Cavity; Salivary Gland Squamous Cell Carcinoma; Stage III Salivary Gland Cancer; Stage III Squamous Cell Carcinoma of the Hypopharynx; Stage III Squamous Cell Carcinoma of the Larynx; Stage III Squamous Cell Carcinoma of the Lip and Oral Cavity; Stage III Squamous Cell Carcinoma of the Nasopharynx; Stage III Squamous Cell Carcinoma of the Oropharynx; Stage III Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity; Stage III Verrucous Carcinoma of the Larynx; Stage III Verrucous Carcinoma of the Oral Cavity; Stage IV Salivary Gland Cancer; Stage IV Squamous Cell Carcinoma of the Hypopharynx; Stage IV Squamous Cell Carcinoma of the Larynx; Stage IV Squamous Cell Carcinoma of the Lip and Oral Cavity; Stage IV Squamous Cell Carcinoma of the Nasopharynx; Stage IV Squamous Cell Carcinoma of the Oropharynx; Stage IV Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity; Stage IV Verrucous Carcinoma of the Larynx; Stage IV Verrucous Carcinoma of the Oral Cavity; Tongue Cancer; Untreated Metastatic Squamous Neck Cancer With Occult Primary |
National Cancer Institute (NCI) |
2008-07 | PHASE1 |
| NCT00672594 | COMPLETED | Prostate Cancer; Prostatectomy |
Duke University |
2006-07 | PHASE2 |
| NCT00387920 | COMPLETED | Central Nervous System Metastases; Childhood Central Nervous System Choriocarcinoma; Childhood Central Nervous System Embryonal Tumor; Childhood Central Nervous System Germ Cell Tumor; Childhood Central Nervous System Germinoma; Childhood Central Nervous System Mixed Germ Cell Tumor; Childhood Central Nervous System Teratoma; Childhood Central Nervous System Yolk Sac Tumor; Recurrent Childhood Central Nervous System Embryonal Tumor; Unspecified Childhood Solid Tumor, Protocol Specific |
National Cancer Institute (NCI) |
2006-10 | PHASE1 |
| NCT01122888 | TERMINATED | Adult Giant Cell Glioblastoma; Adult Glioblastoma; Adult Gliosarcoma; Adult Solid Neoplasm; Recurrent Adult Brain Neoplasm |
National Cancer Institute (NCI) |
2009-12 | PHASE1 |
| NCT00513695 | COMPLETED | Inflammatory Breast Cancer; Male Breast Cancer; Stage II Breast Cancer; Stage IIIA Breast Cancer; Stage IIIB Breast Cancer; Stage IIIC Breast Cancer |
University of Washington |
2007-06 | PHASE2 |
| NCT00821327 | COMPLETED | Urothelial Cancer |
US Oncology Research |
2008-08 | PHASE2 |
| NCT00606008 | COMPLETED | Anaplastic Astrocytoma; Glioblastoma |
H. Lee Moffitt Cancer Center and Research Institute |
2007-03 | PHASE2 |
| NCT01118351 | TERMINATED | Recurrent Bladder Cancer; Transitional Cell Carcinoma of the Bladder |
Case Comprehensive Cancer Center |
2008-10 | PHASE2 |
| NCT00979966 | COMPLETED | Non-clear Cell Renal Cell Cancer |
Central European Society for Anticancer Drug Research |
2009-07 | PHASE2 |
| NCT00864721 | COMPLETED | Non Small Cell Lung Cancer |
US Oncology Research |
2009-02 | PHASE2 |
| NCT00357318 | COMPLETED | Unspecified Adult Solid Tumor, Protocol Specific |
National Cancer Institute (NCI) |
2006-06 | PHASE1 |
| NCT00923117 | TERMINATED | Glioblastoma Multiforme; Malignant Gliomas; Anaplastic Gliomas |
National Cancer Institute (NCI) |
2008-06 | PHASE2 |
| NCT01068769 | COMPLETED | Gastrointestinal Stromal Tumor |
Suzanne George, MD |
2010-02 | PHASE2 |
| NCT00543049 | COMPLETED | Platinum Refractory Epithelial Ovarian Cancer; Primary Cancer of the Peritoneum; Cancer of the Fallopian Tube |
AGO Study Group |
2007-09 | PHASE2 |
| NCT01147822 | COMPLETED | Carcinoma, Renal Cell |
Novartis Pharmaceuticals |
2010-05-19 | PHASE2 |
| NCT00720941 | COMPLETED | Carcinoma, Renal Cell |
Novartis Pharmaceuticals |
2008-08-14 | PHASE3 |
| NCT00768144 | COMPLETED | Ovarian Cancer; Fallopian Tube Cancer; Peritoneal Cancer |
Dana-Farber Cancer Institute |
2008-09 | PHASE2 |
| NCT00678119 | COMPLETED | Renal Cell Carcinoma |
Argos Therapeutics |
2008-01 | PHASE2 |
| NCT00777478 | UNKNOWN | Colorectal Cancer |
Radboud University Medical Center |
2008-12 | PHASE1 |
| NCT01042795 | TERMINATED | Urothelial Carcinoma; Bladder Cancer |
University of Michigan |
2009-09 | PHASE2 |
| NCT01238055 | COMPLETED | Advanced Gastric Cancer |
Samsung Medical Center |
2008-11 | PHASE2 |
| NCT00631618 | COMPLETED | Metastatic Melanoma |
California Pacific Medical Center Research Institute |
2007-09 | PHASE2 |
| NCT00510640 | COMPLETED | Cancer; Thyroid Carcinoma |
University Hospital, Bordeaux |
2007-08 | PHASE2 |
| NCT00753727 | UNKNOWN | Soft Tissue Sarcoma |
Australasian Sarcoma Study Group |
2008-09 | PHASE1; PHASE2 |
| NCT01258348 | COMPLETED | Metastatic Renal Cell Cancer |
Eli Lilly and Company |
2008-07 | PHASE1 |
| NCT00620347 | COMPLETED | Lung Cancer |
National Cancer Center, Korea |
2008-03 | PHASE2 |
| NCT00397488 | COMPLETED | Bladder Cancer; Transitional Cell Cancer of the Renal Pelvis and Ureter; Urethral Cancer |
Memorial Sloan Kettering Cancer Center |
2006-09 | PHASE2 |
| NCT00619268 | COMPLETED | Metastatic Renal Cell Carcinoma |
Centre Leon Berard |
2008-02 | PHASE2 |
| NCT00434109 | COMPLETED | Neuroendocrine Tumor; Islet Cell Tumor |
H. Lee Moffitt Cancer Center and Research Institute |
2006-11 | PHASE2 |
| NCT01271712 | COMPLETED | Gastrointestinal Stromal Tumors |
Bayer |
2011-01-04 | PHASE3 |
| NCT00392496 | COMPLETED | Adult Diffuse Large Cell Lymphoma; Recurrent Adult Diffuse Large Cell Lymphoma; Stage IV Adult Diffuse Large Cell Lymphoma |
National Cancer Institute (NCI) |
2007-02 | PHASE2 |
| NCT01082809 | COMPLETED | Advanced Biliary Tract Adenocarcinoma |
Samsung Medical Center |
2009-03 | PHASE2 |
| NCT00388037 | COMPLETED | Recurrent Fallopian Tube Cancer; Recurrent Ovarian Epithelial Cancer; Recurrent Primary Peritoneal Cavity Cancer; Stage IIIA Fallopian Tube Cancer; Stage IIIA Ovarian Epithelial Cancer; Stage IIIA Primary Peritoneal Cavity Cancer; Stage IIIB Fallopian Tube Cancer; Stage IIIB Ovarian Epithelial Cancer; Stage IIIB Primary Peritoneal Cavity Cancer; Stage IIIC Fallopian Tube Cancer; Stage IIIC Ovarian Epithelial Cancer; Stage IIIC Primary Peritoneal Cavity Cancer; Stage IV Fallopian Tube Cancer; Stage IV Ovarian Epithelial Cancer; Stage IV Primary Peritoneal Cavity Cancer |
National Cancer Institute (NCI) |
2007-01 | PHASE2 |
| NCT00910039 | TERMINATED | Cognitive/Functional Effects; Metastatic Cancer; Unspecified Adult Solid Tumor, Protocol Specific |
Case Comprehensive Cancer Center |
2009-04 | PHASE2 |
| NCT00967603 | COMPLETED | Pancreatic Cancer |
IRCCS San Raffaele |
2008-02 | PHASE2 |
| NCT00474786 | COMPLETED | Renal Cell Carcinoma |
Pfizer |
2007-09 | PHASE3 |
| NCT00392444 | COMPLETED | Advanced Malignant Mesothelioma; Recurrent Malignant Mesothelioma |
National Cancer Institute (NCI) |
2007-02 | PHASE2 |
| NCT01286896 | COMPLETED | Malignant Solid Tumour |
The Netherlands Cancer Institute |
2011-04-11 | PHASE1 |
| NCT00698815 | COMPLETED | Recurrent Non-Small Cell Lung Carcinoma; Stage IIIB Non-Small Cell Lung Cancer AJCC v7; Stage IV Non-Small Cell Lung Cancer AJCC v7 |
National Cancer Institute (NCI) |
2008-04-15 | PHASE2 |
| NCT00676650 | TERMINATED | Prostatic Neoplasms |
Pfizer |
2008-07 | PHASE3 |
| NCT00798889 | COMPLETED | Solid Tumors |
Pfizer |
2004-03 | |
| NCT00400569 | COMPLETED | Liposarcoma; Leiomyosarcoma; Fibrosarcoma; Malignant Fibrous Histiocytoma |
H. Lee Moffitt Cancer Center and Research Institute |
2006-11 | PHASE2 |
| NCT01039519 | COMPLETED | Gastrointestinal Stromal Tumor |
Synta Pharmaceuticals Corp. |
2010-01 | PHASE2 |
| NCT01069770 | UNKNOWN | Clear Cell Renal Cell Carcinoma; Metastasis |
Korean Urological Oncology Society |
2009-07 | PHASE2 |
| NCT00699374 | TERMINATED | Carcinoma, Hepatocellular |
Pfizer |
2008-07 | PHASE3 |
| NCT01024920 | COMPLETED | Carcinoma, Renal Cell |
Boehringer Ingelheim |
2009-12-16 | PHASE2 |
| NCT01210053 | UNKNOWN | Non-small Cell Lung Cancer |
Third Military Medical University |
2010-09 | PHASE2 |
| NCT01064310 | COMPLETED | Carcinoma, Renal Cell |
Novartis Pharmaceuticals |
2010-05-17 | PHASE3 |
| NCT00975806 | TERMINATED | Renal Cell Carcinoma |
Celgene |
2009-09-01 | PHASE1; PHASE2 |
| NCT00879619 | TERMINATED | Prostate Cancer; Adenocarcinoma of the Prostate; Recurrent Prostate Cancer; Stage I Prostate Cancer; Stage III Prostate Cancer; Stage IV Prostate Cancer |
John P. Fruehauf |
2009-07 | PHASE1; PHASE2 |
| NCT00673504 | COMPLETED | Pancreatic Cancer |
Central European Society for Anticancer Drug Research |
2008-04 | PHASE2 |
| NCT00480935 | TERMINATED | Renal Cell Carcinoma |
University Health Network, Toronto |
2007-10 | PHASE2 |
| NCT00537056 | COMPLETED | Kidney Neoplasms; Carcinoma, Renal Cell; Kidney (Renal Cell) Cancer |
Stanford University |
2007-10 | |
| NCT00931450 | UNKNOWN | Breast Cancer |
Institut Català d'Oncologia |
2009-03 | PHASE1; PHASE2 |
| NCT00953446 | TERMINATED | Renal Cell Carcinoma |
Beth Israel Deaconess Medical Center |
2010-06-15 | |
| NCT00372424 | COMPLETED | Breast Cancer |
Pfizer |
2006-12 | PHASE1 |
| NCT01219751 | UNKNOWN | Metastatic Renal Cell Carcinoma |
Asan Medical Center |
2008-06 | PHASE2 |
| NCT01506336 | COMPLETED | Gastro Intestinal Stromal Tumor |
AB Science |
2008-10 | PHASE2 |
| NCT00451048 | COMPLETED | Chronic Myelomonocytic Leukemia; de Novo Myelodysplastic Syndromes; Myelodysplastic Syndromes; Secondary Myelodysplastic Syndromes |
National Cancer Institute (NCI) |
2007-02 | PHASE2 |
| NCT00853372 | COMPLETED | Advanced Renal Cell Carcinoma |
Amgen |
2009-05-28 | PHASE2 |
| NCT00453895 | COMPLETED | Adrenocortical Carcinoma |
University of Wuerzburg |
2007-07 | PHASE2 |
| NCT00706706 | COMPLETED | Carcinoma, Renal Cell |
Pfizer |
2008-07 | PHASE4 |
| NCT00729833 | TERMINATED | Advanced Cancer; Advanced Solid Tumors |
Pfizer |
2008-09 | PHASE1 |
| NCT00705874 | COMPLETED | Cancer |
Progen Pharmaceuticals |
2006-05 | PHASE1 |
| NCT00609622 | TERMINATED | Colorectal Neoplasms |
Pfizer |
2008-04 | PHASE2 |
| NCT01548170 | COMPLETED | Cancer |
Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal |
2011-04 | PHASE1 |
| NCT00520533 | TERMINATED | Renal Cell Carcinoma (RCC) |
Ludwig Institute for Cancer Research |
2008-02 | PHASE1 |
| NCT01121562 | COMPLETED | Pancreatic Neuroendocrine Tumors |
Pfizer |
2010-07 | PHASE2 |
| NCT00486538 | COMPLETED | Advanced Renal Cell Carcinoma |
AbbVie (prior sponsor, Abbott) |
2007-06 | PHASE2 |
| NCT00869011 | UNKNOWN | Renal Cell Carcinoma |
Charite University, Berlin, Germany |
2009-12 | PHASE3 |
| NCT00890110 | UNKNOWN | Renal Cell Cancer |
Hadassah Medical Organization |
2009-06 | PHASE1; PHASE2 |
| NCT00695292 | COMPLETED | Small Cell Lung Cancer |
SCRI Development Innovations, LLC |
2008-06 | PHASE2 |
| NCT00890747 | COMPLETED | Accelerated Phase Chronic Myelogenous Leukemia; Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome; Acute Undifferentiated Leukemia; Adult Acute Lymphoblastic Leukemia in Remission; Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities; Adult Acute Myeloid Leukemia With Del(5q); Adult Acute Myeloid Leukemia With Inv(16)(p13;q22); Adult Acute Myeloid Leukemia With t(15;17)(q22;q12); Adult Acute Myeloid Leukemia With t(16;16)(p13;q22); Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); Adult Grade III Lymphomatoid Granulomatosis; Adult Langerhans Cell Histiocytosis; Adult Nasal Type Extranodal NK/T-cell Lymphoma; Aggressive NK-cell Leukemia; AIDS-related Diffuse Large Cell Lymphoma; AIDS-related Diffuse Mixed Cell Lymphoma; AIDS-related Diffuse Small Cleaved Cell Lymphoma; AIDS-related Immunoblastic Large Cell Lymphoma; AIDS-related Lymphoblastic Lymphoma; AIDS-related Malignancies; AIDS-related Small Noncleaved Cell Lymphoma; Anaplastic Large Cell Lymphoma; Angioimmunoblastic T-cell Lymphoma; Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative; Chronic Eosinophilic Leukemia; Chronic Myelomonocytic Leukemia; Chronic Neutrophilic Leukemia; Chronic Phase Chronic Myelogenous Leukemia; Clear Cell Renal Cell Carcinoma; Cutaneous B-cell Non-Hodgkin Lymphoma; de Novo Myelodysplastic Syndromes; Essential Thrombocythemia; Extramedullary Plasmacytoma; Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue; Hepatosplenic T-cell Lymphoma; HIV Infection; HIV-associated Hodgkin Lymphoma; Intraocular Lymphoma; Isolated Plasmacytoma of Bone; Light Chain Deposition Disease; Mast Cell Leukemia; Myelodysplastic Syndrome With Isolated Del(5q); Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable; Myeloid/NK-cell Acute Leukemia; Nodal Marginal Zone B-cell Lymphoma; Noncutaneous Extranodal Lymphoma; Osteolytic Lesions of Multiple Myeloma; Peripheral T-cell Lymphoma; Plasma Cell Neoplasm; Polycythemia Vera; Post-transplant Lymphoproliferative Disorder; Previously Treated Myelodysplastic Syndromes; Primary Myelofibrosis; Primary Systemic Amyloidosis; Progressive Hairy Cell Leukemia, Initial Treatment; Prolymphocytic Leukemia; Recurrent Adult Acute Lymphoblastic Leukemia; Recurrent Adult Acute Myeloid Leukemia; Recurrent Adult Burkitt Lymphoma; Recurrent Adult Diffuse Large Cell Lymphoma; Recurrent Adult Diffuse Mixed Cell Lymphoma; Recurrent Adult Diffuse Small Cleaved Cell Lymphoma; Recurrent Adult Grade III Lymphomatoid Granulomatosis; Recurrent Adult Hodgkin Lymphoma; Recurrent Adult Immunoblastic Large Cell Lymphoma; Recurrent Adult Lymphoblastic Lymphoma; Recurrent Adult T-cell Leukemia/Lymphoma; Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma; Recurrent Grade 1 Follicular Lymphoma; Recurrent Grade 2 Follicular Lymphoma; Recurrent Grade 3 Follicular Lymphoma; Recurrent Mantle Cell Lymphoma; Recurrent Marginal Zone Lymphoma; Recurrent Mycosis Fungoides/Sezary Syndrome; Recurrent Renal Cell Cancer; Recurrent Small Lymphocytic Lymphoma; Refractory Chronic Lymphocytic Leukemia; Refractory Hairy Cell Leukemia; Refractory Multiple Myeloma; Relapsing Chronic Myelogenous Leukemia; Stage IV Renal Cell Cancer; T-cell Large Granular Lymphocyte Leukemia; Testicular Lymphoma; Unspecified Adult Solid Tumor, Protocol Specific; Waldenström Macroglobulinemia |
National Cancer Institute (NCI) |
2009-08 | PHASE1 |
| NCT00731211 | COMPLETED | Renal Cell Carcinoma |
SCRI Development Innovations, LLC |
2008-09 | PHASE2 |
| NCT00864864 | COMPLETED | Glioblastoma; Brain Tumor |
Massachusetts General Hospital |
2007-05 | EARLY_PHASE1 |
| NCT00792025 | COMPLETED | Bladder Cancer; Transitional Cell Cancer of the Renal Pelvis and Ureter |
Institut Curie |
2008-12 | PHASE2 |
| NCT00330564 | TERMINATED | Von Hippel-Lindau Syndrome; Renal Cell Carcinoma; Hemangioblastoma |
M.D. Anderson Cancer Center |
2006-05 | PHASE2 |
| NCT01215565 | TERMINATED | Hepatocellular Carcinoma; Fibrolamellar Hepatocellular Carcinoma |
Assistance Publique - Hôpitaux de Paris |
2009-10 | PHASE2 |
| NCT00796861 | TERMINATED | Ascites |
Milton S. Hershey Medical Center |
2007-05 | PHASE2 |
| NCT00748358 | COMPLETED | Prostatic Neoplasms; Neoplasms, Hormone-Dependent; Tumor Markers, Biological; Survival Rate; Disease-Free Survival |
Assistance Publique - Hôpitaux de Paris |
2008-03 | PHASE2 |
| NCT00795171 | UNKNOWN | Hormone Refractory Prostate Cancer |
Medical University of Vienna |
2008-11 | PHASE2 |
| NCT00616122 | TERMINATED | Breast Cancer |
University of California, San Francisco |
2006-03-01 | PHASE1; PHASE2 |
| NCT00459979 | COMPLETED | Kidney Cancer |
Case Comprehensive Cancer Center |
2007-03 | PHASE2 |
| NCT00961571 | TERMINATED | Metastatic Colorectal Cancer |
Georgetown University |
2009-08 | PHASE2 |
| NCT00541008 | COMPLETED | Kidney Cancer |
UNICANCER |
2007-09-05 | PHASE2 |
| NCT00673816 | TERMINATED | Von Hippel-Lindau Syndrome |
National Eye Institute (NEI) |
2008-05 | PHASE1; PHASE2 |
| NCT01168440 | COMPLETED | Von Hippel-Lindau Disease |
Association Pour La Recherche des Thérapeutiques Innovantes en Cancérologie |
2010-03 | PHASE2 |
| NCT00626509 | UNKNOWN | Kidney Cancer |
Gruppo Italiano Carcinoma Renale |
2008-02 | PHASE2 |
| NCT00905021 | TERMINATED | Metastatic Breast Cancer |
Baylor Breast Care Center |
2010-03 | PHASE1; PHASE2 |
| NCT00535379 | UNKNOWN | Glioblastoma Multiforme |
Medical University Innsbruck |
2007-10 | PHASE2 |
| NCT00495625 | TERMINATED | Liver Cancer |
H. Lee Moffitt Cancer Center and Research Institute |
2006-10 | PHASE2 |
| NCT01091207 | COMPLETED | Gastrointestinal Stromal Tumors |
Samsung Medical Center |
2009-11 | PHASE2 |
| NCT01019798 | UNKNOWN | Non Small Cell Lung Cancer |
Taipei Medical University Hospital |
2009-01 | PHASE2 |
| NCT00524316 | TERMINATED | Liver Cancer |
Roswell Park Cancer Institute |
2007-04 | PHASE2 |
| NCT00814021 | COMPLETED | Kidney Cancer; Metastatic Cancer |
Institut Claudius Regaud |
2009-04 | PHASE2 |
| NCT01118039 | UNKNOWN | Bladder Cancer; Transitional Cell Cancer of the Renal Pelvis and Ureter; Urethral Cancer |
Hospital del Mar |
2006-07 | PHASE2 |
| NCT00437372 | COMPLETED | Cancer; Head and Neck Cancer; Pelvic Cancer; Nervous System Neoplasms; Thoracic Neoplasms |
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University |
2007-03 | PHASE1 |
| NCT01743300 | COMPLETED | Healthy |
Leiden University Medical Center |
2007-07 | PHASE1 |
| NCT00824538 | TERMINATED | Breast Cancer |
University of California, San Francisco |
2009-02 | PHASE2 |
| NCT00459875 | COMPLETED | Kidney Cancer |
Memorial Sloan Kettering Cancer Center |
2007-03 | PHASE2 |
| NCT00474994 | COMPLETED | Adult Malignant Fibrous Histiocytoma of Bone; Desmoid Tumor; Endometrial Cancer; Ovarian Cancer; Sarcoma; Small Intestine Cancer |
Memorial Sloan Kettering Cancer Center |
2007-04 | PHASE2 |
| NCT00521092 | WITHDRAWN | AIDS-related Kaposi Sarcoma; Classic Kaposi Sarcoma |
National Cancer Institute (NCI) |
2009-01 | PHASE2 |
| NCT00430261 | COMPLETED | Lung Cancer; Adenocarcinoma |
Swedish Medical Center |
2007-01 | PHASE2 |
| NCT00668863 | COMPLETED | Unresectable or Metastatic Colorectal Cancer |
Pfizer |
2008-05 | PHASE2 |
| NCT00656669 | COMPLETED | Breast Cancer |
Indiana University |
2008-04 | |
| NCT01024205 | COMPLETED | Kidney Cancer |
Barts and the London School of Medicine and Dentistry |
2007-08 | PHASE2 |
| NCT00555620 | COMPLETED | Stomach Neoplasms |
Pfizer |
2008-05 | PHASE1 |
| NCT00425386 | COMPLETED | Kidney Cancer |
OHSU Knight Cancer Institute |
2006-08 | PHASE2 |
| NCT00953459 | TERMINATED | Lung Cancer |
European Organisation for Research and Treatment of Cancer - EORTC |
2009-02 | PHASE2 |
| NCT00457392 | COMPLETED | Carcinoma, Non-Small Cell Lung |
Pfizer |
2007-07 | PHASE3 |
| NCT00720148 | COMPLETED | Solid Tumors |
Emory University |
2008-02 | PHASE1 |
| NCT00717587 | UNKNOWN | Kidney Cancer |
Abramson Cancer Center at Penn Medicine |
2008-06 | PHASE2 |
| NCT00806663 | COMPLETED | Metastatic Colorectal Cancer; Liver Metastases |
Central European Society for Anticancer Drug Research |
2008-08 | PHASE2 |
| NCT00471276 | COMPLETED | Breast Neoplasms |
Pfizer |
2007-08 | PHASE2 |
| NCT00267748 | COMPLETED | Carcinoma, Renal Cell |
Pfizer |
2005-12 | PHASE2 |
| NCT00462553 | COMPLETED | Adenocarcinoma of the Pancreas; Recurrent Pancreatic Cancer; Stage III Pancreatic Cancer; Stage IV Pancreatic Cancer; Unspecified Adult Solid Tumor, Protocol Specific |
National Cancer Institute (NCI) |
2007-03 | PHASE1 |
| NCT00618319 | COMPLETED | GIST |
Biogen |
2008-02 | PHASE2 |
| NCT00787787 | TERMINATED | Adult Primary Hepatocellular Carcinoma; Advanced Adult Primary Liver Cancer; Localized Unresectable Adult Primary Liver Cancer; Recurrent Adult Primary Liver Cancer |
University of Washington |
2008-09 | PHASE2 |
| NCT00528619 | COMPLETED | Neoplasms |
Pfizer |
2006-11 | PHASE1 |
| NCT00936832 | WITHDRAWN | Colorectal Cancer; Metastatic Cancer |
Federation Francophone de Cancerologie Digestive |
2009-04 | PHASE2 |
| NCT00482755 | COMPLETED | Breast Cancer |
NCIC Clinical Trials Group |
2009-04-08 | PHASE2 |
| NCT00526656 | COMPLETED | Bladder Cancer |
Case Comprehensive Cancer Center |
2007-09 | PHASE2 |
| NCT00457691 | COMPLETED | Metastatic Colorectal Cancer |
Pfizer |
2007-06 | PHASE3 |
| NCT00387335 | COMPLETED | Metastatic Squamous Neck Cancer With Occult Primary Squamous Cell Carcinoma; Recurrent Metastatic Squamous Neck Cancer With Occult Primary; Recurrent Squamous Cell Carcinoma of the Hypopharynx; Recurrent Squamous Cell Carcinoma of the Larynx; Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity; Recurrent Squamous Cell Carcinoma of the Nasopharynx; Recurrent Squamous Cell Carcinoma of the Oropharynx; Recurrent Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity; Stage IV Squamous Cell Carcinoma of the Hypopharynx; Stage IV Squamous Cell Carcinoma of the Larynx; Stage IV Squamous Cell Carcinoma of the Lip and Oral Cavity; Stage IV Squamous Cell Carcinoma of the Nasopharynx; Stage IV Squamous Cell Carcinoma of the Oropharynx; Stage IV Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity |
National Cancer Institute (NCI) |
2006-08 | PHASE2 |
| NCT00730353 | COMPLETED | Esophageal Cancer |
Hoosier Cancer Research Network |
2008-08 | PHASE2 |
| NCT00709995 | COMPLETED | Metastatic Renal Cell Carcinoma |
Eli Lilly and Company |
2008-06-30 | PHASE2 |
| NCT00265798 | ACTIVE_NOT_RECRUITING | Gastrointestinal Stromal Tumor |
National Cancer Institute (NCI) |
2005-09-14 | PHASE2 |
| NCT00393939 | COMPLETED | Breast Neoplasms |
Pfizer |
2007-02 | PHASE3 |
| NCT00555256 | COMPLETED | Non-Small Cell Lung Cancer |
Washington University School of Medicine |
2007-11 | PHASE1 |
| NCT00422344 | COMPLETED | Renal Cell Carcinoma; Kidney Cancer |
Memorial Sloan Kettering Cancer Center |
2006-10 | PHASE1 |
| NCT00581789 | COMPLETED | Non Small Cell Lung Cancer |
University of Wisconsin, Madison |
2007-08 | PHASE1 |
| NCT00265317 | COMPLETED | Carcinoma, Non-Small-Cell Lung |
Pfizer |
2006-06 | PHASE2 |
| NCT00891475 | COMPLETED | Carcinoma, Renal Cell |
Kidney Cancer Research Bureau |
2008-05 | PHASE1; PHASE2 |
| NCT01070706 | COMPLETED | Breast Cancer |
Jungsil Ro |
2009-03 | PHASE1; PHASE2 |
| NCT00662025 | COMPLETED | Advanced/Metastatic Breast Cancer |
Pfizer |
2008-04 | PHASE2 |
| NCT00555672 | COMPLETED | Stomach Neoplasms |
Pfizer |
2008-08 | PHASE1 |
| NCT00435409 | COMPLETED | Breast Neoplasms |
Pfizer |
2007-02 | PHASE3 |
| NCT00616109 | COMPLETED | Extensive-Stage Small Cell Lung Cancer |
University of Michigan Rogel Cancer Center |
2007-09 | PHASE2 |
| NCT00372775 | COMPLETED | Non-Small Cell Lung Cancer |
Pfizer |
2007-03 | PHASE2 |
| NCT00732992 | COMPLETED | Neoplasm, Malignant |
Pfizer |
2008-08 | PHASE1 |
| NCT00372567 | TERMINATED | Gastrointestinal Stromal Tumor |
Pfizer |
2007-06 | PHASE3 |
| NCT00373113 | TERMINATED | Breast Neoplasms |
Pfizer |
2006-11 | PHASE3 |
| NCT00573404 | TERMINATED | Gastrointestinal Stromal Tumor |
Vanderbilt-Ingram Cancer Center |
2007-07 | PHASE1 |
| NCT00556205 | WITHDRAWN | Renal Cell Carcinoma |
Massachusetts General Hospital |
2009-09 | PHASE2 |
| NCT00663559 | COMPLETED | Carcinoma Renal Cells |
Spanish Oncology Genito-Urinary Group |
2008-02 | PHASE2 |
| NCT00818350 | UNKNOWN | Urinary Bladder Neoplasms |
Campania Younger Oncologists Association |
2009-01 | PHASE1; PHASE2 |
| NCT00849186 | COMPLETED | Kidney Cancer |
Roswell Park Cancer Institute |
2007-08 | |
| NCT00417885 | TERMINATED | Breast Neoplasms |
Pfizer |
2007-06 | PHASE1; PHASE2 |
| NCT00631410 | COMPLETED | Colorectal Neoplasms |
Pfizer |
2008-01 | PHASE1 |
| NCT00411151 | COMPLETED | Gastric Adenocarcinoma; Barrett Esophagus |
Johannes Gutenberg University Mainz |
2006-12 | PHASE2 |
| NCT00553696 | COMPLETED | Stomach Neoplasms |
Pfizer |
2007-11 | PHASE1 |
| NCT00678288 | TERMINATED | Carcinoma, Renal Cell |
Bayer |
2008-04 | PHASE2 |
| NCT00499473 | COMPLETED | Adult Anaplastic Astrocytoma; Adult Diffuse Astrocytoma; Adult Giant Cell Glioblastoma; Adult Glioblastoma; Adult Gliosarcoma; Adult Mixed Glioma; Adult Oligodendroglioma; Adult Pineal Gland Astrocytoma |
National Cancer Institute (NCI) |
2007-06 | PHASE2 |
| NCT00599313 | COMPLETED | Metastatic Prostate Cancer |
US Oncology Research |
2007-03 | PHASE2 |
| NCT00371553 | COMPLETED | Relapsed or Cisplatin-Refractory Germ Cell Cancer |
British Columbia Cancer Agency |
2006-11 | PHASE2 |
| NCT00373256 | COMPLETED | Breast Neoplasms |
Pfizer |
2006-11 | PHASE3 |
| NCT00570635 | COMPLETED | Gastrointestinal Stromal Tumors; Gastrointestinal Neoplasms |
Exelixis |
2007-12 | PHASE2 |
| NCT00688766 | TERMINATED | Gastrointestinal Stromal Tumors |
Infinity Pharmaceuticals, Inc. |
2008-08 | PHASE3 |
| NCT00428597 | TERMINATED | Carcinoma, Islet Cell; Carcinoma, Pancreas |
Pfizer |
2007-06 | PHASE3 |
| NCT00338884 | COMPLETED | Carcinoma, Renal Cell |
Pfizer |
2006-09 | PHASE2 |
| NCT00482911 | TERMINATED | Intraocular Melanoma; Malignant Conjunctival Neoplasm |
National Institutes of Health Clinical Center (CC) |
2007-04 | PHASE2 |
| NCT00904657 | COMPLETED | Blood Pressure |
University of Cologne |
2008-10 | PHASE1 |
| NCT00113516 | COMPLETED | Non-small Cell Lung Cancer |
Pfizer |
2005-09 | PHASE2 |
| NCT00514137 | COMPLETED | Refractory Multiple Myeloma; Stage I Multiple Myeloma; Stage II Multiple Myeloma; Stage III Multiple Myeloma |
National Cancer Institute (NCI) |
2007-09 | PHASE2 |
| NCT00389974 | COMPLETED | Cervical Adenocarcinoma; Cervical Adenosquamous Cell Carcinoma; Cervical Squamous Cell Carcinoma; Recurrent Cervical Cancer; Stage IVB Cervical Cancer |
National Cancer Institute (NCI) |
2007-01 | PHASE2 |
| NCT00511849 | COMPLETED | Neoplasms |
Pfizer |
2005-11 | PHASE1 |
| NCT00387426 | TERMINATED | Accelerated Phase Chronic Myelogenous Leukemia; Acute Undifferentiated Leukemia; Adult Acute Lymphoblastic Leukemia in Remission; Adult Acute Myeloid Leukemia in Remission; Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities; Adult Acute Myeloid Leukemia With Inv(16)(p13;q22); Adult Acute Myeloid Leukemia With t(15;17)(q22;q12); Adult Acute Myeloid Leukemia With t(16;16)(p13;q22); Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative; Blastic Phase Chronic Myelogenous Leukemia; Chronic Myelomonocytic Leukemia; Chronic Phase Chronic Myelogenous Leukemia; Mast Cell Leukemia; Meningeal Chronic Myelogenous Leukemia; Primary Myelofibrosis; Progressive Hairy Cell Leukemia, Initial Treatment; Prolymphocytic Leukemia; Recurrent Adult Acute Lymphoblastic Leukemia; Recurrent Adult Acute Myeloid Leukemia; Refractory Chronic Lymphocytic Leukemia; Refractory Hairy Cell Leukemia; Relapsing Chronic Myelogenous Leukemia; Secondary Acute Myeloid Leukemia; Stage I Chronic Lymphocytic Leukemia; Stage II Chronic Lymphocytic Leukemia; Stage III Chronic Lymphocytic Leukemia; Stage IV Chronic Lymphocytic Leukemia; T-cell Large Granular Lymphocyte Leukemia; Untreated Adult Acute Lymphoblastic Leukemia; Untreated Adult Acute Myeloid Leukemia; Untreated Hairy Cell Leukemia |
National Cancer Institute (NCI) |
2006-09 | PHASE2 |
| NCT00399152 | COMPLETED | Renal Cancer; GIST |
AEterna Zentaris |
2006-10 | PHASE1 |
| NCT00444314 | COMPLETED | Metastatic Renal Cell Carcinoma |
CASI pharmaceuticals, Inc. |
2007-02 | PHASE2 |
| NCT00398112 | COMPLETED | B-cell Chronic Lymphocytic Leukemia; Recurrent Small Lymphocytic Lymphoma; Refractory Chronic Lymphocytic Leukemia |
National Cancer Institute (NCI) |
2007-08 | PHASE2 |
| NCT00599924 | COMPLETED | Colorectal Neoplasms; Neoplasms |
Pfizer |
2005-09 | PHASE1 |
| NCT00453310 | COMPLETED | Extragonadal Germ Cell Tumor; Ovarian Cancer; Teratoma; Testicular Germ Cell Tumor |
Memorial Sloan Kettering Cancer Center |
2007-03 | PHASE2 |
| NCT00291577 | COMPLETED | Breast Neoplasms |
Pfizer |
2006-07 | PHASE1 |
| NCT00514228 | COMPLETED | Liver Cancer |
Swiss Cancer Institute |
2007-07 | PHASE2 |
| NCT00748163 | WITHDRAWN | Lung Cancer |
Masonic Cancer Center, University of Minnesota |
2008-08 | PHASE2 |
| NCT00462982 | COMPLETED | Kidney Cancer; Melanoma (Skin); Metastatic Cancer |
Memorial Sloan Kettering Cancer Center |
2007-03 | PHASE2 |
| NCT00457743 | COMPLETED | Gastrointestinal Stromal Tumors |
Pfizer |
2005-01 | PHASE1; PHASE2 |
| NCT00471328 | COMPLETED | Gastrointestinal Stromal Tumors |
Novartis Pharmaceuticals |
2007-03 | PHASE3 |
| NCT00402415 | TERMINATED | Tumors |
Yale University |
2006-02 | PHASE1 |
| NCT00782834 | TERMINATED | Gastrointestinal Stromal Tumors |
Fox Chase Cancer Center |
2008-07 | PHASE2 |
| NCT00617253 | COMPLETED | Cancer; Renal Cell Carcinoma |
Novo Nordisk A/S |
2007-07-12 | PHASE2 |
| NCT00299741 | COMPLETED | Prostate Cancer |
Massachusetts General Hospital |
2006-03 | PHASE2 |
| NCT00226811 | COMPLETED | Stomach Neoplasms |
Pfizer |
2006-01 | PHASE2 |
| NCT00434356 | TERMINATED | Metastatic Breast Cancer |
Genentech, Inc. |
2007-03 | PHASE2 |
| NCT00522249 | TERMINATED | Carcinoma, Renal Cell |
The Methodist Hospital Research Institute |
2007-05 | PHASE1; PHASE2 |
| NCT00421512 | COMPLETED | Metastatic Renal Cell Carcinoma; Kidney Cancer |
Memorial Sloan Kettering Cancer Center |
2006-03 | PHASE1 |
| NCT00434226 | TERMINATED | Non-Small Cell Lung Cancer |
Genentech, Inc. |
2007-03 | PHASE2 |
| NCT00583063 | COMPLETED | Solid Tumors |
University of Chicago |
2007-10 | EARLY_PHASE1 |
| NCT00247676 | COMPLETED | Liver Neoplasms; Unresectable Hepatocellular Carcinoma |
Pfizer |
2006-02 | PHASE2 |
| NCT00491738 | TERMINATED | Renal Cell Carcinoma |
Genentech, Inc. |
2007-08 | PHASE2 |
| NCT00712504 | COMPLETED | Advanced Solid Tumors; Non Small Cell Lung Cancer |
Pfizer |
2004-07 | PHASE1 |
| NCT00137423 | COMPLETED | Carcinoma, Renal Cell Metastasis |
Pfizer |
2005-05 | PHASE2 |
| NCT00397787 | COMPLETED | Acinar Cell Adenocarcinoma of the Pancreas; Duct Cell Adenocarcinoma of the Pancreas; Recurrent Pancreatic Cancer; Stage IV Pancreatic Cancer |
National Cancer Institute (NCI) |
2006-11 | PHASE2 |
| NCT00113529 | COMPLETED | Carcinoma, Renal Cell |
Pfizer |
2004-10 | PHASE1; PHASE2 |
| NCT00496223 | TERMINATED | Melanoma |
H. Lee Moffitt Cancer Center and Research Institute |
2006-09 | PHASE1; PHASE2 |
| NCT00378911 | COMPLETED | Recurrent Uterine Sarcoma; Uterine Leiomyosarcoma |
National Cancer Institute (NCI) |
2006-10 | PHASE2 |
| NCT00092001 | COMPLETED | Carcinoma, Non-Small-Cell Lung |
Pfizer |
2005-01 | PHASE2 |
| NCT00089648 | COMPLETED | Carcinoma, Renal Cell |
Pfizer |
2004-12 | PHASE2 |
| NCT00056693 | COMPLETED | Neuroendocrine Tumors |
Pfizer |
2003-04 | PHASE2 |
| NCT00417677 | TERMINATED | Renal Cell Carcinoma |
Wyeth is now a wholly owned subsidiary of Pfizer |
2007-03 | PHASE1; PHASE2 |
| NCT00861419 | COMPLETED | Advanced Solid Tumors |
Amgen |
2005-12 | PHASE1 |
| NCT00550810 | UNKNOWN | Prostate Cancer; Hormone Refractory |
Alberta Health services |
2007-10 | PHASE2 |
| NCT01070186 | WITHDRAWN | Renal Cell Carcinoma |
Jonsson Comprehensive Cancer Center |
2010-10 | PHASE2 |
(data from https://clinicaltrials.gov, updated on 2023-09-13)
Mechanism and Biochemical Profile
Appendix RUO and cGMP Quality Standards
| Quality Dimension | RUO (Research Use Only) | cGMP (Current Good Manufacturing Practice) |
|---|---|---|
| Clinical Applicability | Prohibited in human clinical trials or medical diagnostics. | Mandatory for human clinical trials (Phase I–III) and therapies. |
| Regulatory Status | Non-regulated grade; exempt from drug manufacturing laws. | Legally enforced by health authorities (e.g., FDA, EMA, NMPA). |
| Facility Environment | Unclassified analytical or research laboratories. | Validated Cleanrooms (ISO Class 5–8) with continuous monitoring. |
| Quality Control | Basic purity and activity testing. | Rigorous safety release testing (Sterility, Endotoxin, Mycoplasma). |
| Process Validation | Basic equipment calibration; no process validation required. | Full qualification (IQ/OQ/PQ) and complete batch records. |
| Quality Assurance | Vendor self-declared without required formal QMS. | Mandatory QA/QC unit, Change Control, CAPA, and vendor audits. |
| Regulatory Impact | High risk of IND rejection if used as a critical raw material. | Required for IND/NDA filings, supported by Drug Master Files (DMF). |
Footnotes
Regulatory Note: Governed by FDA (21 CFR Parts 210/211/312), EMA (EudraLex Vol 4), ICH Guidelines (E6/Q7/Q9/Q10), and compendial standards (USP <71>/<85>/<1043>).
- Sunitinib (SU-11248) Solubility in DMSO
- Sunitinib (SU-11248) Stock Solution
- Sunitinib (SU-11248) Storage
- Sunitinib (SU-11248) Stability
- Sunitinib (SU-11248) Molecular Weight
- Sunitinib (SU-11248) SMILES
- Sunitinib (SU-11248) CAS Number
- Sunitinib (SU-11248) Chemical Structure (2D and 3D)
- Sunitinib (SU-11248) SDS|MSDS