CAS No. 61318-91-0
Batch:
Purity:99.98
Chemical Structure
Check the
Sulconazole Nitrate
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 1-[2-[(4-chlorophenyl)methylsulfanyl]-2-(2,4-dichlorophenyl)ethyl]imidazole;nitric acid | |
|---|---|---|
| CAS Number | 61318-91-0 | |
| Molecular Formula |
C18H15Cl3N2S.HNO3 |
|
| Molecular Weight (MW) | 460.76 | |
| SMILES | C1=CC(=CC=C1CSC(CN2C=CN=C2)C3=C(C=C(C=C3)Cl)Cl)Cl.[N+](=O)(O)[O-] | |
| InChIKey | CRKGMGQUHDNAPB-UHFFFAOYSA-N |
Sulconazole nitrate is a synthetic imidazole derivative with broad-spectrum antifungal activity against various dermatophytes and yeasts. It targets and inhibits fungal cytochrome P450 14α-demethylase (CYP51), disrupting the ergosterol biosynthesis pathway and compromising membrane structure and permeability. This perturbation disrupts essential membrane-bound enzyme functions, ultimately inhibiting fungal cell growth and survival.
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
92 mg/mL
(199.67 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
92 mg/mL
(199.67 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
Note: Technical data last updated: Sep 1, 2026.