CAS No. 108-30-5
Batch:
Purity:99.73
Chemical Structure
Check the
Succinic anhydride
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 108-30-5 | |
|---|---|---|
| Molecular Formula |
C4H4O3 |
|
| Molecular Weight (MW) | 100.07 | |
| SMILES | C1CC(=O)OC1=O |
Succinic anhydride is a reactive cyclic dicarboxylic anhydride used as a bioconjugation reagent and chemical linker. It covalently modifies nucleophilic functional groups, such as primary amines on lysine residues and hydroxyl groups, yielding succinylated adducts. This chemical modification alters biomolecular surface charge, increases aqueous solubility, and serves as a noncleavable crosslinking moiety in the synthesis of polypeptide-drug conjugates and modified biopolymers.
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
20 mg/mL
(199.86 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- Succinic anhydride Clinical Trials
- Succinic anhydride Solubility in DMSO
- Succinic anhydride Stock Solution
- Succinic anhydride Storage
- Succinic anhydride Stability
- Succinic anhydride Molecular Weight
- Succinic anhydride SMILES
- Succinic anhydride Chemical Structure (2D and 3D)
- Succinic anhydride SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.