CAS No. 330161-87-0

Batch: Purity:99.84
SU6656 Chemical Structure
Chemical Structure
Check the SU6656 product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name N,N-dimethyl-2-oxo-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmethylidene)-1H-indole-5-sulfonamide
CAS Number 330161-87-0
Molecular Formula

C19H21N3O3S

Molecular Weight (MW) 371.45
SMILES CN(C)S(=O)(=O)C1=CC2=C(C=C1)NC(=O)C2=CC3=CC4=C(N3)CCCC4
InChIKey LOGJQOUIVKBFGH-UHFFFAOYSA-N

Ordering Information

Biological Activity

SU6656 is a selective Src family kinase inhibitor targeting Src (IC50 of, Yes (IC50 of, Lyn (IC50 of, and Fyn (IC50 of. By selectively suppressing Src family kinase signaling, SU6656 blocks downstream protein phosphorylation and disrupts key cellular processes, including cell proliferation, cell migration, and cytoskeletal rearrangements in preclinical models. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 74 mg/mL (199.21 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water Insoluble
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.