Stemregenin 1 (SR1) is a potent aryl hydrocarbon receptor (AhR) antagonist. It affects AhR and p38α/mTORC1 signaling by blocking AhR activation, effectively promoting the ex vivo expansion and proliferation of hematopoietic stem cells.
Comprehensive IC50 Values for Stemregenin 1 (SR1) Across Cell-free Enzyme Inhibitory Profiles and Cell-based Functional Assays.
Stemregenin 1 (SR1) is a potent aryl hydrocarbon receptor (AhR) antagonist. It affects AhR and p38α/mTORC1 signaling by blocking AhR activation, effectively promoting the ex vivo expansion and proliferation of hematopoietic stem cells.