SRI-011381 (C381): Mechanism of Action

SRI-011381 (C381) MOA:Targeting TGF-β/SMAD for Neurodegenerative Diseases

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SRI-011381 (C381) is a specific TGF-β/Smad agonist. It affects TGF-β/Smad signaling by increasing TGF-β1 and phosphorylating Smad2/3, effectively promoting cell proliferation and fibrosis while inhibiting apoptosis and ferroptosis.

Primary Applications and Mechanism of Action