SP600125 is a potent, selective, and reversible ATP-competitive JNK inhibitor. It affects JNK/c-Jun and MAPK signaling pathways by blocking JNK phosphorylation and c-Jun activation, effectively inhibiting inflammation, cell proliferation, and apoptosis in various cells.
SP600125 IC50 for Cell-based and Cell-free Assays
Comprehensive IC50 Values for SP600125 Across Cell-free Enzyme Inhibitory Profiles and Cell-based Functional Assays.