CAS No. 6882-68-4
Batch:
Purity:98
Chemical Structure
Check the
Sophoridine
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 6882-68-4 | |
|---|---|---|
| Molecular Formula |
C15H24N2O |
|
| Molecular Weight (MW) | 248.36 | |
| SMILES | C1CC2C3CCCN4C3C(CCC4)CN2C(=O)C1 |
Sophoridine is a naturally occurring quinolizidine alkaloid with broad bioactivity across multiple biological systems. It modulates cellular signaling pathways, including MAPK/ERK and PI3K/AKT, to inhibit cell proliferation, migration, and invasion in various cancer cell models. Furthermore, Sophoridine suppresses pro-inflammatory responses and induces cell cycle arrest and apoptosis, contributing to its observed anti-tumor, immunomodulatory, and neuroprotective pharmacological effects.
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
49 mg/mL
(197.29 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.