CAS No. 62717-42-4
Batch:
Purity:99.57
Chemical Structure
Check the
SKF38393 HCl
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 5-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol;hydrochloride | |
|---|---|---|
| CAS Number | 62717-42-4 | |
| Molecular Formula |
C16H17NO2 . HCl |
|
| Molecular Weight (MW) | 291.77 | |
| SMILES | C1CNCC(C2=CC(=C(C=C21)O)O)C3=CC=CC=C3.Cl | |
| InChIKey | YEWHJCLOUYPAOH-UHFFFAOYSA-N |
SKF38393 HCl is a selective agonist of dopamine D1 and D5 receptors. Upon binding to dopamine D1-like receptors, it stimulates adenylyl cyclase activity, leading to increased intracellular cyclic AMP (cAMP) accumulation and downstream activation of the protein kinase A (PKA) signaling pathway. These cellular events modulate central neurotransmission and influence downstream behavioral phenotypes and motor regulation. [1]
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
58 mg/mL
(198.78 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 6 mg/mL |
| Water | 5 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.