Simvastatin (MK-733) is a lipophilic HMGCR inhibitor. It affects RhoA signaling by blocking mevalonate, reducing cholesterol.
Comprehensive IC50 Values for Simvastatin (MK-733) Across Cell-free Enzyme Inhibitory Profiles and Cell-based Functional Assays.
Simvastatin (MK-733) is a lipophilic HMGCR inhibitor. It affects RhoA signaling by blocking mevalonate, reducing cholesterol.