CAS No. 22199-08-2
Batch:
Purity:98
Chemical Structure
Check the
Silver Sulfadiazine
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 22199-08-2 | |
|---|---|---|
| Molecular Formula |
C10H9AgN4O2S |
|
| Molecular Weight (MW) | 357.14 | |
| SMILES | C1=CN=C(N=C1)[N-]S(=O)(=O)C2=CC=C(C=C2)N.[Ag+] |
Silver sulfadiazine is a broad-spectrum antibacterial agent that functions as a topical antimicrobial by slowly releasing silver ions and sulfadiazine. It acts by binding to bacterial cell membranes and nucleic acids, disrupting cell wall structure, membrane permeability, and cellular respiration. This targeted action inhibits DNA replication and folate biosynthesis pathways, leading to potent bactericidal activity against diverse gram-negative and gram-positive bacteria as well as yeast strains. [1]
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| 4-Methylpyridine | 3 mg/mL |
| DMSO |
0.1 mg/mL
(0.28 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- Silver Sulfadiazine Clinical Trials
- Silver Sulfadiazine Solubility in DMSO
- Silver Sulfadiazine Stock Solution
- Silver Sulfadiazine Storage
- Silver Sulfadiazine Stability
- Silver Sulfadiazine Molecular Weight
- Silver Sulfadiazine SMILES
- Silver Sulfadiazine Chemical Structure (2D and 3D)
- Silver Sulfadiazine SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.