Semaxanib (SU5416): Selectivity & Specificity
Semaxanib (SU5416) is a potent inhibitor of C57BL/6J hepatic cytosol (AHRb isoform) (2.1 nM), FLT1, KDR, FLT4, PDGFRB, FLT3, KIT, MET, and RET. Semaxanib (SU5416) exhibits the greatest inhibitory potency toward C57BL/6J hepatic cytosol (AHRb isoform) (IC50 = 2.1 nM).