Home Biosimilar Antibodies Immunology & Inflammation CD markers Selicrelumab (Anti-TNFRSF5 / CD40)
For research use only. Not for use in humans.

Selicrelumab (Anti-TNFRSF5 / CD40)

Synonyms: null

Selicrelumab (anti-TNFRSF5 / CD40) is a human immunoglobulin G2 (IgG2) monoclonal antibody agonist of the cell surface receptor CD40 with potential immunostimulatory and antineoplastic activities. It induces changes in the tumor microenvironment and can be used for the research of pancreatic cancer and neoadjuvant tudies. MW: 146.2 kD.

Selicrelumab (Anti-TNFRSF5 / CD40)

Quality Control

Batch: Purity: 99% Protein concentration: 6.6mg/ml Endotoxin Level: ＜1EU/mg
99

Specificity

Name Citation CD38 CD45 CD39 CD88 CD73 Others
RBN013209 0
MK-0159 0
CD38 inhibitor 1 (compound 78c) 7
AB680 0
NQ301 2 TXA2 receptor
SodiuM Metatungstate 3
PMX-53 3
LY-3475070 2
Expand to Check More
1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Mechanism of Action

Description
Selicrelumab (anti-TNFRSF5 / CD40) is a human immunoglobulin G2 (IgG2) monoclonal antibody agonist of the cell surface receptor CD40 with potential immunostimulatory and antineoplastic activities. It induces changes in the tumor microenvironment and can be used for the research of pancreatic cancer and neoadjuvant tudies. MW: 146.2 kD.
References

Product Details

CAS No. 1622140-49-1
Molecular Weight 146.2
Isotype Human IgG2SA
Source CHO
Purification AKTA
Sterility 0.2 μM filtered
Formulation 100 mM Pro-Ac, 20mM Arg, pH5.0
Storage
(From the date of receipt)		 Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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