CAS No. 7759-35-5
Batch:
Purity:99.96
Chemical Structure
Check the
Segesterone acetate
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 7759-35-5 | |
|---|---|---|
| Molecular Formula |
C23H30O4 |
|
| Molecular Weight (MW) | 370.48 | |
| SMILES | CC(=O)OC1(C(C)=O)C(=C)CC2C3CCC4=CC(=O)CCC4C3CCC12C |
Segesterone acetate (Nestoron, ST-1435) is a synthetic progestin that acts as a progesterone receptor agonist with an ECof. Activation of progesterone receptor signaling regulates target gene transcription involved in reproductive function. By selectively activating the progesterone receptor without exhibiting androgenic or estrogenic activity, segesterone acetate suppresses ovulation and demonstrates potent progestational response. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
74 mg/mL
(199.74 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 37 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- Segesterone acetate Clinical Trials
- Segesterone acetate Solubility in DMSO
- Segesterone acetate Stock Solution
- Segesterone acetate Storage
- Segesterone acetate Stability
- Segesterone acetate Molecular Weight
- Segesterone acetate SMILES
- Segesterone acetate Chemical Structure (2D and 3D)
- Segesterone acetate SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.