CAS No. 61281-38-7
Batch:
Purity:99.89
Chemical Structure
Check the
Schisandrin A
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| CAS Number | 61281-38-7 | |
|---|---|---|
| Molecular Formula |
C24H32O6 |
|
| Molecular Weight (MW) | 416.51 | |
| SMILES | CC1CC2=CC(=C(C(=C2C3=C(C(=C(C=C3CC1C)OC)OC)OC)OC)OC)OC |
Biological Activity
Schisandrin A is a natural bioactive lignan compound and adiponectin receptor 2 (AdipoR2) agonist with liver-protective, antioxidant, and antitumor activities. It modulates downstream complex pathways by suppressing the NF-kB and MAPK signaling cascades. Consequently, Schisandrin A inhibits cancer cell proliferation, attenuates pro-inflammatory cytokine production, and suppresses cell migration and invasion in preclinical tumor models. [1]
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
83 mg/mL
(199.27 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Reference
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Note: Technical data last updated: Sep 1, 2026.