CAS No. 158732-59-3
Chemical Structure
Check the
Salvianolic acid F
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | (E)-3-[2-[(E)-2-(3,4-dihydroxyphenyl)ethenyl]-3,4-dihydroxyphenyl]prop-2-enoic acid | |
|---|---|---|
| CAS Number | 158732-59-3 | |
| Molecular Formula |
C17H14O6 |
|
| Molecular Weight (MW) | 314.29 | |
| SMILES | O=C(O)/C=C/C1=CC=C(O)C(O)=C1/C=C/C2=CC=C(O)C(O)=C2 | |
| InChIKey | PULWRMOKQNWQBD-LZSLGQGWSA-N |
Salvianolic acid F is a KRAS inhibitor targeting KRAS G12D that suppresses NF-kB, MMP-9, and nitric oxide production. It attenuates the PI3K/AKT and EP300/PI3K/AKT signaling cascades, leading to reduced cancer cell proliferation, migration, and invasion, as well as increased apoptosis. Furthermore, it inhibits KRAS-dependent lung cancer and ovarian cancer cell growth in experimental models.[1][2]
|
Concentration
Volume
Mass
|
|---|
Note: Technical data last updated: Sep 1, 2026.