CAS No. 115841-09-3
Batch:
Purity:99.95
Chemical Structure
Check the
Salvianolic acid C
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| IUPAC Name | (2R)-3-(3,4-dihydroxyphenyl)-2-[(E)-3-[2-(3,4-dihydroxyphenyl)-7-hydroxy-1-benzofuran-4-yl]prop-2-enoyl]oxypropanoic acid | |
|---|---|---|
| CAS Number | 115841-09-3 | |
| Molecular Formula |
C26H20O10 |
|
| Molecular Weight (MW) | 492.43 | |
| InChIKey | GCJWPRRNLSHTRY-VURDRKPISA-N |
Biological Activity
Salvianolic acid C is a polyphenolic natural product that acts as a non-competitive inhibitor of cytochrome P450 2C8 (CYP2C8) and a moderate mixed inhibitor of cytochrome P450 2J2 (CYP2J2). Inhibition of CYP2C8 and CYP2J2 modulates xenobiotic metabolism and arachidonic acid biotransformation pathways. These enzymatic perturbations alter cellular drug clearance mechanisms and regulate vascular signaling and lipid mediator phenotypes. [1]
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
98 mg/mL
(199.01 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 98 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Reference
Jump to
Note: Technical data last updated: Sep 1, 2026.