CAS No. 53003-10-4

Batch: Purity:97
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Salinomycin (Procoxacin) Chemical Structure
Chemical Structure
Check the Salinomycin (Procoxacin) product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name (2R)-2-[(2R,5S,6R)-6-[(2S,3S,4S,6R)-6-[(3S,5S,7R,9S,10S,12R,15R)-3-[(2R,5R,6S)-5-ethyl-5-hydroxy-6-methyloxan-2-yl]-15-hydroxy-3,10,12-trimethyl-4,6,8-trioxadispiro[4.1.57.35]pentadec-13-en-9-yl]-3-hydroxy-4-methyl-5-oxooctan-2-yl]-5-methyloxan-2-yl]butanoic acid
CAS Number 53003-10-4
Molecular Formula

C42H70O11
Molecular Weight (MW) 751.00
SMILES CCC(C1CCC(C(O1)C(C)C(C(C)C(=O)C(CC)C2C(CC(C3(O2)C=CC(C4(O3)CCC(O4)(C)C5CCC(C(O5)C)(CC)O)O)C)C)O)C)C(=O)O
InChIKey KQXDHUJYNAXLNZ-XQSDOZFQSA-N

Ordering Information

Biological Activity

Salinomycin (Procoxacin) is a monocarboxylic polyether ionophore antibiotic with potent selective activity against cancer stem cells (CSCs). It selectively targets CD44-high breast cancer stem cells, impairing mammosphere formation and inducing apoptotic cell death. In preclinical cancer models, salinomycin inhibits oncogenic signaling pathways, leading to suppressed tumor cell growth, reduced CSC populations, and decreased metastatic capability. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 100 mg/mL (133.15 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 100 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.