S63845 is a potent, selective MCL-1 inhibitor. It affects BAX/BAK-dependent apoptosis and interferon signaling pathways by binding to the MCL-1 BH3 groove and displacing pro-apoptotic proteins, effectively promoting caspase-dependent apoptosis in cancer cells.
S63845: Mechanism of Action
S63845 MOA：Targeting MCL-1/Mitochondrial Apoptotic Pathway for Hematological Malignancies