RSL3 is a potent, selective, and covalent GPX4 inhibitor. It affects ferroptosis and lipid peroxidation signaling, by covalently binding to the active site selenocysteine of GPX4, promoting the lethal accumulation of lipid reactive oxygen species and inducing iron-dependent cell death.
RSL3: Mechanism of Action
RSL3 MOA：Targeting GPX4/Ferroptosis Pathway for Cancer Therapeutics
Jump to
- RSL3 Solubility in DMSO
- RSL3 Stock Solution
- RSL3 Storage
- RSL3 Stability
- RSL3 Molecular Weight
- RSL3 SMILES
- RSL3 CAS Number
- RSL3 Chemical Structure (2D and 3D)
- RSL3 Sigma (sml2234)? Try a better option.
- RSL3 MedChemExpress (HY-100218A)? Try a better option.
- RSL3 Cayman (19288)? Try a better option.
- RSL3 Tocris (6118)? Try a better option.
- RSL3 APExBIO (B6095)? Try a better option.
- RSL3 SDS｜MSDS