CAS No. 91374-20-8
| IUPAC Name | 4-[2-(dipropylamino)ethyl]-1,3-dihydroindol-2-one;hydrochloride | |
|---|---|---|
| CAS Number | 91374-20-8 | |
| Molecular Formula |
C16H24N2O.HCl |
|
| Molecular Weight (MW) | 296.84 | |
| SMILES | CCCN(CCC)CCC1=C2CC(=O)NC2=CC=C1.Cl | |
| InChIKey | XDXHAEQXIBQUEZ-UHFFFAOYSA-N |
Ropinirole HCl (SKF-101468A) is a selective dopamine D2 receptor agonist with a Ki of. By selectively stimulating dopamine D2 receptors, ropinirole mimics endogenous dopamine action and activates downstream signaling cascades, including inhibition of adenylyl cyclase activity. This receptor activation promotes signaling through dopamine-dependent pathways, suppressing elevated prolactin release and modulating motor function phenotypes in preclinical models. [1]
|
Concentration
Volume
Mass
|
|---|
| Solvent | Solubility & Note |
|---|---|
| Water | 59 mg/mL |
| DMSO |
30 mg/mL
(101.06 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | Insoluble |
| Water | 60 mg/mL |
| DMSO |
10 mg/mL
(33.68 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | Insoluble |
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
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