CAS No. 123441-03-2

Batch: Purity:99.98
Rivastigmine Chemical Structure
Chemical Structure
Check the Rivastigmine product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name [3-[(1S)-1-(dimethylamino)ethyl]phenyl] N-ethyl-N-methylcarbamate
CAS Number 123441-03-2
Molecular Formula

C14H22N2O2

Molecular Weight (MW) 250.34
SMILES CCN(C)C(=O)OC1=CC=CC(=C1)C(C)N(C)C
InChIKey XSVMFMHYUFZWBK-NSHDSACASA-N

Ordering Information

Biological Activity

Rivastigmine is a brain-selective cholinesterase inhibitor that targets acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). By inhibiting both AChE and BChE enzymes, it prevents the hydrolysis of acetylcholine, thereby increasing extracellular acetylcholine levels and enhancing cholinergic neurotransmission across central nervous system pathways. Downstream, this elevation in cholinergic signaling supports synaptic activity and modulates cognitive cellular responses in preclinical neurodegeneration models. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.