LEE011 (Ribociclib) is stable under recommended storage conditions.
Recommended storage conditions are listed in the table below.
| Form | Storage Temp | Shelf Life |
|---|---|---|
| Powder | -20°C | 3 years |
| In Solvent | -80°C | 1 year |
| In Solvent | -20°C | 1 month |
Check the
LEE011 (Ribociclib)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
8 mg/mL
(18.41 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
8 mg/mL
(18.41 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
7 mg/mL
(16.1 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
22 mg/mL
(50.62 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
20 mg/mL
(46.02 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
- LEE011 (Ribociclib) Mechanism of Action: CDK4/6 Inhibition in HR+/HER2- Breast Cancer Cell Research
- LEE011 (Ribociclib) Clinical Trials
- LEE011 (Ribociclib): Selectivity & Specificity
- LEE011 (Ribociclib) Working Concentration | Cell Culture | Treatment
- LEE011 (Ribociclib) Solubility in DMSO
- LEE011 (Ribociclib) Stock Solution
- LEE011 (Ribociclib) Storage
- LEE011 (Ribociclib) Combination Database
- LEE011 (Ribociclib) Molecular Weight
- LEE011 (Ribociclib) SMILES
- LEE011 (Ribociclib) CAS Number
- LEE011 (Ribociclib) Chemical Structure (2D and 3D)
- LEE011 (Ribociclib) IC50 for Cell-based and Cell-free Assays
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- LEE011 (Ribociclib) SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.