2D Structure
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2D chemical structural formula diagram.
3D Structure
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This 3D model represents a theoretically simulated conformation and is for reference only.
Check the
SNDX-5613 (Revumenib)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | N-ethyl-2-[4-[7-[[4-(ethylsulfonylamino)cyclohexyl]methyl]-2,7-diazaspiro[3.5]nonan-2-yl]pyrimidin-5-yl]oxy-5-fluoro-N-propan-2-ylbenzamide | |
|---|---|---|
| CAS Number | 2169919-21-3 | |
| Molecular Formula |
C32H47FN6O4S |
|
| Molecular Weight (MW) | 630.82 | |
| SMILES | CCN(C(C)C)C(=O)C1=C(OC2=CN=CN=C2N3CC4(CCN(CC4)CC5CCC(CC5)N[S](=O)(=O)CC)C3)C=CC(=C1)F | |
| InChIKey | FRVSRBKUQZKTOW-UHFFFAOYSA-N |
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
25 mg/mL
(39.63 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 25 mg/mL |
| Water | Insoluble |
| DMSO |
100 mg/mL
(158.52 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 25 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- SNDX-5613 (Revumenib) Mechanism of Action: Menin Inhibition in Leukemic Cell Research
- SNDX-5613 (Revumenib) Clinical Trials
- SNDX-5613 (Revumenib) Working Concentration | Cell Culture | Treatment
- SNDX-5613 (Revumenib) Solubility in DMSO
- SNDX-5613 (Revumenib) Stock Solution
- SNDX-5613 (Revumenib) Storage
- SNDX-5613 (Revumenib) Stability
- SNDX-5613 (Revumenib) Combination Database
- SNDX-5613 (Revumenib) Molecular Weight
- SNDX-5613 (Revumenib) SMILES
- SNDX-5613 (Revumenib) CAS Number
- SNDX-5613 (Revumenib) MedChemExpress (HY-136175)? Try a better option.
- SNDX-5613 (Revumenib) Cayman (40758)? Try a better option.
- SNDX-5613 (Revumenib) Abmole (M13387)? Try a better option.
- SNDX-5613 (Revumenib) Sigma (AMBH9A7E9AFC)? Try a better option.
- SNDX-5613 (Revumenib) Tocris (8907)? Try a better option.
- SNDX-5613 (Revumenib) SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.