Relacorilant (CORT125134) SMILES

SMILES:

C[N]1C=C(C=N1)[S;v6](=O)(=O)N2CCC3=CC4=C(CC3(C2)C(=O)C5=CC(=CC=N5)C(F)(F)F)C=N[N]4C6=CC=C(F)C=C6

Chemical Structure

Check the Relacorilant (CORT125134) product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

IUPAC Name	[(4aR)-1-(4-fluorophenyl)-6-(1-methylpyrazol-4-yl)sulfonyl-4,5,7,8-tetrahydropyrazolo[5,4-g]isoquinolin-4a-yl]-[4-(trifluoromethyl)-2-pyridinyl]methanone
CAS Number	1496510-51-0
Molecular Formula	C₂₇H₂₂F₄N₆O₃S
Molecular Weight (MW)	586.56
SMILES	C[N]1C=C(C=N1)[S;v6](=O)(=O)N2CCC3=CC4=C(CC3(C2)C(=O)C5=CC(=CC=N5)C(F)(F)F)C=N[N]4C6=CC=C(F)C=C6
InChIKey	WANIDIGFXJFFEL-SANMLTNESA-N

Concentration Volume Mass

Batch:

All in vitro solubility values are batch-tested experimental data (non-literature values).

Solvent	Solubility & Note
DMSO	100 mg/mL (170.48 mM) (Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol	100 mg/mL
Water	Insoluble
DMSO	100 mg/mL (170.48 mM) (Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol	100 mg/mL
Water	Insoluble

FAQ

Q: Why does a DMSO stock precipitate in media/saline?

A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.

How to fix it?