Raltegravir potassium Clinical Trials

Size	Price	Qty
10mg	USD 147

Clinical Trials

Raltegravir potassium is supported by numerous clinical trials spanning early- to late-stage development. These studies evaluate HIV-1 and HIV-2 seropositivity, healthy volunteers, hepatitis C, and cognitive impairment, while assessing drug interactions, pharmacokinetics, and treatment simplification strategies across completed, recruiting, terminated, and marketing-approved statuses. The research is sponsored by pharmaceutical companies like Merck Sharp & Dohme LLC alongside academic institutions including ANRS and the Kirby Institute.

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
NCT02140255	RECRUITING	HIV Infection	National Institute of Allergy and Infectious Diseases (NIAID)	2015-01-23	PHASE1; PHASE2
NCT04513626	RECRUITING	HIV Infections	Centre de Recherches et d'Etude sur la Pathologie Tropicale et le Sida	2020-09-15	PHASE2
NCT03174977	UNKNOWN	HIV-1-infection	University of California, San Francisco	2018-04-01	EARLY_PHASE1
NCT04258475	UNKNOWN	Calcium Supplementation in HIV Patients Using Raltegravir	Ottawa Hospital Research Institute	2020-12-09	PHASE4
NCT03954327	COMPLETED	Primary Biliary Cholangitis	University of Alberta	2021-03-01	PHASE2
NCT02691065	COMPLETED	HIV	McGill University Health Centre/Research Institute of the McGill University Health Centre	2017-01-20	PHASE4
NCT03311945	COMPLETED	HIV Infections; HIV-1-infection; HIV Seropositivity	Judit Pich	2018-05-02	PHASE3
NCT03333083	TERMINATED	HIV Seropositivity; HIV Infections; HIV-1-infection	Judit Pich	2018-05-03	PHASE3
NCT03394196	TERMINATED	HIV-2 Infection	University of Washington	2018-07-04
NCT03029689	COMPLETED	HIV	Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia	2017-07-28	PHASE3
NCT03732625	UNKNOWN	HIV Infections	Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud	2019-05	PHASE4
NCT01751568	COMPLETED	HIV Infections; Tuberculosis	National Institute of Allergy and Infectious Diseases (NIAID)	2014-11-12	PHASE1; PHASE2
NCT03374358	COMPLETED	HIV Seropositivity; Metabolic Syndrome; Fatty Liver	Helsinki University Central Hospital	2018-01-10	PHASE4
NCT03195452	COMPLETED	Virus-HIV	Nantes University Hospital	2017-11-08	PHASE2
NCT02150993	COMPLETED	HIV-2 Infection	ANRS, Emerging Infectious Diseases	2016-01-26	PHASE2; PHASE3
NCT02655471	COMPLETED	HTLV-I Infections; Tropical Spastic Paraparesis	Universidad Peruana Cayetano Heredia	2017-07-01	EARLY_PHASE1
NCT02210715	COMPLETED	HIV; Fatty Liver; Nonalcoholic Steatohepatitis	McGill University Health Centre/Research Institute of the McGill University Health Centre	2015-03	PHASE4
NCT01618305	COMPLETED	HIV Infections	Westat	2013-09-05	PHASE4
NCT01896921	COMPLETED	HIV	University of Maryland, Baltimore	2013-09	PHASE3
NCT02273765	COMPLETED	HIV-1 Infection; Tuberculosis	ANRS, Emerging Infectious Diseases	2015-09-11	PHASE3
NCT03667547	COMPLETED	Human Immunodeficiency Virus (HIV) Infection	Merck Sharp & Dohme LLC	2018-09-27	PHASE4
NCT01867320	COMPLETED	HTLV-I Infection	National Institute of Neurological Disorders and Stroke (NINDS)	2013-09-05	EARLY_PHASE1
NCT03205566	COMPLETED	Hiv	Guy's and St Thomas' NHS Foundation Trust	2017-09-19	PHASE4
NCT02577042	COMPLETED	Aging-related Inflammation in HIV-infected Patients	Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia	2015-10-15	PHASE4
NCT01780831	COMPLETED	HIV Infections	National Institute of Allergy and Infectious Diseases (NIAID)	2014-01-28	PHASE1
NCT01900106	COMPLETED	HIV Infection	University of Modena and Reggio Emilia	2013-11	PHASE3
NCT02336074	COMPLETED	HIV	Imperial College London	2015-11-27	PHASE2
NCT01829802	UNKNOWN	Chronic Infection With HIV	Pedro Cahn	2014-05	PHASE4
NCT02212379	COMPLETED	HIV-1 Infection	ANRS, Emerging Infectious Diseases	2015-01	PHASE2
NCT01854762	TERMINATED	HIV; Pregnancy	Fundação Bahiana de Infectologia	2015-06-01	PHASE2; PHASE3
NCT02116660	TERMINATED	HIV Infections	Merck Sharp & Dohme LLC	2014-09-03	PHASE2
NCT03537404	COMPLETED	Healthy	R-Pharm	2017-04-24	PHASE1
NCT02284035	COMPLETED	AIDS	Juan A. Arnaiz	2015-09-27	PHASE3
NCT01601626	TERMINATED	HIV Infection; Tuberculosis	Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections	2013-07-13	PHASE2
NCT01900015	COMPLETED	HCV Coinfection; HIV Infection	Juan Macías	2014-02-03	PHASE4
NCT02099474	COMPLETED	HIV-1 Infection; PREGNANCY	ANRS, Emerging Infectious Diseases	2014-06-30	PHASE2
NCT01902186	TERMINATED	HIV Infection; Osteopenia	Giovanni Di Perri	2014-09	PHASE4
NCT01641367	COMPLETED	HIV-1 Infection	Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections	2013-02-22	PHASE4
NCT01978743	COMPLETED	HIV; HIV-associated Neurocognitive Disorder; Neurotoxicity	Massachusetts General Hospital	2014-01
NCT02025868	UNKNOWN	HIV Infection	ANRS, Emerging Infectious Diseases	2013-03	PHASE2
NCT02219672	UNKNOWN	AIDS/HIV PROBLEM	Peking Union Medical College	2014-07	PHASE3
NCT01147107	COMPLETED	Hepatitis C, Chronic; HIV Infection	University of Hawaii	2014-02	PHASE4
NCT02351908	COMPLETED	HIV	St Stephens Aids Trust	2015-03	PHASE4
NCT02383355	COMPLETED	HIV	Radboud University Medical Center	2015-03-01	PHASE4
NCT02611895	COMPLETED	HIV-1 Infection	University Hospital, Montpellier	2015-03
NCT01825031	COMPLETED	Human Immunodeficiency Virus	Anna Griffiths, MRC	2013-06	PHASE3
NCT01231685	COMPLETED	HIV; Hepatitis C; Liver Fibrosis	McGill University Health Centre/Research Institute of the McGill University Health Centre	2011-12	PHASE2
NCT01784302	COMPLETED	HIV	Helen Reynolds	2014-04	PHASE1
NCT02131233	COMPLETED	HIV Infection	Merck Sharp & Dohme LLC	2014-05-23	PHASE3
NCT01605890	COMPLETED	HIV-2 Infection	ANRS, Emerging Infectious Diseases	2012-07	PHASE2
NCT01844310	UNKNOWN	AIDS/HIV PROBLEM	Peking Union Medical College	2013-05
NCT02097108	COMPLETED	HIV Infections	Arbeitsgemeinschaft medikamentoese Tumortherapie	2014-05	PHASE2
NCT01291459	UNKNOWN	HIV	Association Pour la Recherche en Infectiologie	2011-09	PHASE2
NCT01989910	COMPLETED	HIV-1 Infection	Taipei Veterans General Hospital, Taiwan	2013-09	PHASE4
NCT01453192	COMPLETED	HIV-1 Infection; Chronic Renal Insufficiency	ANRS, Emerging Infectious Diseases	2011-12	PHASE3
NCT02247687	TERMINATED	HIV-1 Infection; Treatment Resistant Disorders; Viremia	ANRS, Emerging Infectious Diseases	2014-12	PHASE3
NCT02473367	COMPLETED	HIV Infection	Merck Sharp & Dohme LLC	2015-06-23	PHASE1
NCT01275183	COMPLETED	Head and Neck Cancer	New Mexico Cancer Research Alliance	2010-12	EARLY_PHASE1
NCT01285050	COMPLETED	HIV Infection; Hepatitis C	Johns Hopkins University	2011-01	PHASE4
NCT01679964	COMPLETED	HIV Infection; Adverse Drug Reaction; Quality of Life	Lin, Hsi-Hsun, M.D.	2012-07	PHASE4
NCT01352715	COMPLETED	HIV-1 Infection	Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections	2012-03-13	PHASE3
NCT02489487	COMPLETED	HIV-infection	Viriom	2014-09	PHASE1
NCT01453933	UNKNOWN	HIV Infection; Endothelial Dysfunction	UMC Utrecht	2012-01	PHASE4
NCT01154673	COMPLETED	Acute HIV Infection	University of Toronto	2011-11	PHASE2; PHASE3
NCT01767701	COMPLETED	Relapsing Remitting Multiple Sclerosis	Queen Mary University of London	2013-04	PHASE2
NCT01576731	COMPLETED	HIV Infection	Hospital Clinic of Barcelona	2012-07	PHASE4
NCT01450189	COMPLETED	HIV	University of North Carolina, Chapel Hill	2011-10
NCT01258439	COMPLETED	HIV; Cardiovascular Disease	St Vincent's Hospital, Sydney	2010-11	PHASE4
NCT01204905	COMPLETED	HIV Infections	University of Maryland, Baltimore	2010-09
NCT01343225	UNKNOWN	HIV	East Carolina University	2011-05	PHASE4
NCT01000285	COMPLETED	Leukemia-Lymphoma, Adult T-Cell	Washington University School of Medicine	2010-09	PHASE1; PHASE2
NCT01480713	COMPLETED	HIV-1 Infection	IrsiCaixa	2012-05	PHASE3
NCT01978782	COMPLETED	HIV; Depression	Radboud University Medical Center	2014-01	PHASE1
NCT00988039	COMPLETED	Human Immunodeficiency Virus; HIV	Justine Boles	2010-03	PHASE3
NCT01717287	COMPLETED	HIV Infection	Merck Sharp & Dohme LLC	2012-11-16	PHASE2
NCT01930045	COMPLETED	HIV Infections	Merck Sharp & Dohme LLC	2013-10-01	PHASE1
NCT00525733	COMPLETED	HIV Infections	Rockefeller University	2007-10
NCT01620736	WITHDRAWN	Human T-cell Leukemia Virus Type 1 Infection	Washington University School of Medicine	2012-01	PHASE2
NCT01525628	COMPLETED	Hepatitis C, Chronic	Boehringer Ingelheim	2012-04	PHASE1
NCT01214759	COMPLETED	HIV	The University of Texas Health Science Center, Houston	2011-05	PHASE4
NCT00843713	COMPLETED	HIV Infection; Inflammation; Cardiovascular Disease; HIV Infections	University of California, San Francisco	2009-01	PHASE4
NCT01066962	COMPLETED	HIV Infections	ANRS, Emerging Infectious Diseases	2010-08	PHASE3
NCT01448486	TERMINATED	Human Immunodeficiency Virus (HIV); HIV Associated Neurocognitive Disorders (HAND)	St Vincent's Hospital, Sydney	2011-10	PHASE4
NCT01841593	COMPLETED	HIV	St Stephens Aids Trust	2013-04	PHASE1
NCT01332227	COMPLETED	HIV, Combination Therapy	Bristol-Myers Squibb	2011-10	PHASE4
NCT01565889	COMPLETED	Hepatitis C; HIV	Gilead Sciences	2012-03	PHASE1; PHASE2
NCT01330199	COMPLETED	Healthy Adult Females	University of North Carolina, Chapel Hill	2012-02	PHASE1
NCT01033760	COMPLETED	HIV-1 Infections	ANRS, Emerging Infectious Diseases	2010-04	PHASE3
NCT01779687	COMPLETED	HIV; Hypercholesterolaemia	Radboud University Medical Center	2013-03	PHASE1
NCT00976404	COMPLETED	HIV Infection	Robert L. Murphy	2009-11	PHASE2
NCT00485264	COMPLETED	HIV Infections	National Institute of Allergy and Infectious Diseases (NIAID)	2007-09-17	PHASE1; PHASE2
NCT01293123	TERMINATED	HIV	University of California, San Diego	2011-12
NCT01195467	COMPLETED	HIV Infection	St Stephens Aids Trust	2010-10	PHASE3
NCT00811954	COMPLETED	HIV Infection	Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections	2009-05	PHASE3
NCT01424826	COMPLETED	HIV; Tuberculosis	Helen Reynolds	2012-01	PHASE1
NCT00984152	WITHDRAWN	HIV-1 Infections	Rush University Medical Center	2011-06	PHASE3
NCT01164605	UNKNOWN	HIV Infection	Southern California Institute for Research and Education	2010-10
NCT01234116	COMPLETED	Human Immunodeficiency Virus	Henry Ford Health System	2011-02	PHASE4
NCT00814879	COMPLETED	Acquired Immune Deficiency Syndrome; AIDS; Human Immunodeficiency Virus; HIV Infections	Yale University	2009-05
NCT01022476	COMPLETED	HIV Infection; Liver Failure; Evidence of Liver Transplantation	ANRS, Emerging Infectious Diseases	2010-05	PHASE1; PHASE2
NCT00870363	COMPLETED	HIV Infections	University of California, Davis	2009-04	PHASE4
NCT01420523	TERMINATED	Human Immunodeficiency Virus; Lipohypertrophy	ANRS, Emerging Infectious Diseases	2011-12	PHASE2
NCT01785160	COMPLETED	Healthy	Boehringer Ingelheim	2013-02	PHASE1
NCT01059422	COMPLETED	HIV Infections; Tuberculosis	Central Institute of Epidemiology, Moscow, Russia	2010-10	PHASE4
NCT01384734	COMPLETED	Infection, Human Immunodeficiency Virus	ViiV Healthcare	2011-07-26	PHASE2
NCT01231516	COMPLETED	Infection, Human Immunodeficiency Virus; HIV Infections	ViiV Healthcare	2010-10-26	PHASE3
NCT01335620	COMPLETED	HIV	Imperial College London	2011-04	PHASE4
NCT00762892	COMPLETED	HIV Infections	The University of Texas Health Science Center, Houston	2009-01	PHASE4
NCT01327482	COMPLETED	HIV	University of Washington	2011-10
NCT01105611	UNKNOWN	HIV Infections; Hepatitis C	St. James's Hospital, Ireland	2010-08	PHASE4
NCT01025427	COMPLETED	HIV; HIV Infections	University of California, San Francisco	2009-12	PHASE4
NCT01533259	COMPLETED	Acquired Immunodeficiency Syndrome; HIV Infections	Gilead Sciences	2012-01	PHASE3
NCT01173510	WITHDRAWN	HIV Infections; Acquired Immune Deficiency Syndrome	Community Research Initiative of New England	2010-08-23	PHASE4
NCT00677300	COMPLETED	HIV Infections	Dallas VA Medical Center	2009-01	PHASE4
NCT01622673	COMPLETED	HIV Infections	Merck Sharp & Dohme LLC	2012-06	PHASE1
NCT01245101	TERMINATED	HIV	University of Miami	2010-11	PHASE4
NCT01270802	COMPLETED	HIV	Indiana University	2011-04	PHASE4
NCT00931463	COMPLETED	HIV Infections	Kirby Institute	2009-09	PHASE4
NCT01513122	COMPLETED	HIV	Kirby Institute	2010-02	PHASE4
NCT01114425	COMPLETED	HIV Infections	Groupe d'Etude sur le Risque d'Exposition des Soignants aux Agents Infectieux	2010-11-01	PHASE3
NCT01225705	WITHDRAWN	HIV; Hepatitis C	University Hospital, Bonn	2010-10	PHASE4
NCT00734344	COMPLETED	Acute HIV Infection	University of Alabama at Birmingham	2008-09
NCT01318096	UNKNOWN	HBV Coinfection; HIV Infections	Yunnan AIDS Care Center	2011-03
NCT00939874	COMPLETED	HIV; Osteopenia; Osteoporosis; HIV Infections	St Vincent's Hospital, Sydney	2009-10	PHASE4
NCT00887653	COMPLETED	HIV; Hyperlipidemia; Hypertriglyceridemia; HIV Infections	The Miriam Hospital	2009-05	PHASE3
NCT01201239	UNKNOWN	HIV	Shanghai Public Health Clinical Center	2010-09	PHASE4
NCT00537394	COMPLETED	HIV Infections	National Institute of Allergy and Infectious Diseases (NIAID)	2008-01	PHASE3
NCT01087840	COMPLETED	HIV Prevention; HIV Infections	Andrew Carr	2010-07	PHASE4
NCT01529749	COMPLETED	HIV-1 Infection	Felipe Garcia	2012-02	PHASE4
NCT01531647	COMPLETED	Healthy Volunteer	Hoffmann-La Roche	2012-01	PHASE1
NCT01227824	COMPLETED	Infection, Human Immunodeficiency Virus I	ViiV Healthcare	2010-10-19	PHASE3
NCT00931801	COMPLETED	HIV	Community Research Initiative of New England	2009-12	PHASE4
NCT00808184	COMPLETED	Solid Tumor	National University Hospital, Singapore	2010-04	PHASE4
NCT01294761	COMPLETED	HIV Infections	National Center for Global Health and Medicine, Japan	2011-02
NCT00781287	TERMINATED	Human Immunodeficiency Virus	University of Washington	2009-02	PHASE4
NCT00654147	COMPLETED	HIV Infections	Margaret A. Fischl, M.D.	2008-04	PHASE2
NCT01042652	UNKNOWN	HIV; HIV Infections	Centers for Disease Control and Prevention, China	2011-02
NCT00807443	COMPLETED	HIV-1; HIV Infections	Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal	2009-09	PHASE2
NCT00667433	COMPLETED	HIV Infections	David A Wohl, MD	2008-06	PHASE1
NCT00656175	COMPLETED	HIV Infections; Lipodystrophy	University of California, Los Angeles	2008-09	PHASE2
NCT01288417	COMPLETED	HIV Infections; HCV Infections	Radboud University Medical Center	2011-08	PHASE1
NCT00808002	COMPLETED	HIV Infections	Germans Trias i Pujol Hospital	2009-02	PHASE3
NCT00822315	COMPLETED	HIV Infections; Tuberculosis	ANRS, Emerging Infectious Diseases	2009-07	PHASE2
NCT01325051	COMPLETED	Healthy Volunteer	Angela Kashuba, PharmD	2011-04	PHASE1
NCT00785967	WITHDRAWN	HIV Infections	McGill University Health Centre/Research Institute of the McGill University Health Centre	2009-01	PHASE3
NCT00749580	COMPLETED	Virus Diseases; HIV	University of South Florida	2008-11
NCT00874523	COMPLETED	HIV Infection	Kirby Institute	2009-07	PHASE3
NCT00745368	COMPLETED	HIV Infections	University of Rochester	2008-09
NCT01289951	COMPLETED	Human Immunodeficiency Virus; Hepatitis C	Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal	2010-12	PHASE1
NCT00752856	COMPLETED	HIV Infections	University of California, San Diego	2008-08-26	PHASE2
NCT00809718	COMPLETED	Healthy	The University of Texas Health Science Center at San Antonio	2009-02	PHASE1
NCT00773708	COMPLETED	HIV Infections	Germans Trias i Pujol Hospital	2009-03	PHASE4
NCT01214486	COMPLETED	HIV	University of Nebraska	2010-10-01
NCT01241773	COMPLETED	Hepatitis C Virus	Tibotec Pharmaceuticals, Ireland	2010-10	PHASE1
NCT00641641	COMPLETED	HIV Infection	Kirby Institute	2008-03
NCT00772720	UNKNOWN	Healthy Volunteers	Hospital Clinic of Barcelona	2010-03	PHASE1
NCT01246804	COMPLETED	HIV Infections; Depression; Mild Cognitive Impairment	Radboud University Medical Center	2010-11	PHASE1
NCT00729924	COMPLETED	HIV Infections	Vanderbilt University	2008-08	PHASE2; PHASE3
NCT00764946	COMPLETED	Human Immunodeficiency Virus	Merck Sharp & Dohme LLC	2008-10	PHASE3
NCT00738569	COMPLETED	HIV	National Jewish Health	2008-07
NCT00562510	TERMINATED	HIV Infections	Pedro Cahn	2008-08	PHASE3
NCT01159132	COMPLETED	HIV Infections	The HIV Netherlands Australia Thailand Research Collaboration	2010-04	PHASE2
NCT01044771	COMPLETED	HIV Infections; Proteinuria	Metropolis Medical	2010-01
NCT00943540	COMPLETED	HIV Infection; HIV Infections	Radboud University Medical Center	2009-07	PHASE2
NCT00708162	COMPLETED	HIV Infection	Gilead Sciences	2008-07	PHASE3
NCT00958100	COMPLETED	HIV/AIDS; Antiretroviral Therapy; HIV Infections	Catholic University of the Sacred Heart	2009-08	PHASE2
NCT00950859	COMPLETED	Infection, Human Immunodeficiency Virus	ViiV Healthcare	2009-08	PHASE2
NCT01121809	COMPLETED	HIV-1 Infection; HIV Infections	Hospitales Universitarios Virgen del Rocío	2010-04	PHASE4
NCT00745823	TERMINATED	HIV	Merck Sharp & Dohme LLC	2008-09	PHASE3
NCT00672932	COMPLETED	HIV Infections	University of California, San Francisco	2008-04
NCT00661960	COMPLETED	HIV Infections; AIDS	University of California, Davis	2008-03
NCT01101893	COMPLETED	Infection, Human Immunodeficiency Virus	ViiV Healthcare	2010-04	PHASE1
NCT00752037	COMPLETED	HIV Infections	Saint Michael's Medical Center	2008-09	PHASE4
NCT01027182	COMPLETED	Human Immunodeficiency Virus	Changi General Hospital	2009-12	PHASE1
NCT00528892	COMPLETED	HIV Infections	Hospital Clinic of Barcelona	2008-01	PHASE3
NCT00772590	COMPLETED	HIV Infections	Kirby Institute	2009-03	PHASE4
NCT02182375	COMPLETED	Healthy	Boehringer Ingelheim	2010-01	PHASE1
NCT00594646	COMPLETED	HIV Infections	Fenway Community Health	2008-02	PHASE4
NCT00863668	WITHDRAWN	HIV Infection; HIV Infections	University of Minnesota	2009-03
NCT00782301	WITHDRAWN	Hepatitis B; Human Immunodeficiency Virus; Hepatitis C, Chronic	ViiV Healthcare	2009-03	PHASE4
NCT00830804	COMPLETED	HIV-1 Infections	Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections	2009-04	PHASE2
NCT00632970	TERMINATED	HIV Infections	George Washington University	2008-02	PHASE4
NCT00787774	UNKNOWN	HIV Infection	Hospital Clinic of Barcelona	2008-11
NCT00768989	TERMINATED	HIV	Bristol-Myers Squibb	2008-11	PHASE2
NCT00944957	UNKNOWN	Sleep Disorders; HIV Infections	University Hospital, Geneva	2009-11
NCT00995241	COMPLETED	HIV Infections	Germans Trias i Pujol Hospital	2009-11	PHASE4
NCT00944307	COMPLETED	HIV Infections	University of Colorado, Denver	2009-07	PHASE1
NCT01047995	COMPLETED	HIV Infections	St Stephens Aids Trust	2009-06	PHASE1
NCT00941083	UNKNOWN	HIV Infections	Hospital Carlos III, Madrid	2009-01	PHASE4
NCT00858962	COMPLETED	HIV Infection; HIV Infections	Yale University	2009-03
NCT00884793	COMPLETED	HIV Infections	University of California, San Francisco	2008-09
NCT00711009	COMPLETED	Human Immunodeficiency Virus Infection	Abbott	2008-07	PHASE3
NCT00982553	COMPLETED	HIV Infections	Imperial College London	2009-09	PHASE1
NCT00751153	UNKNOWN	HIV Infections	Peter J. Ruane, M.D., Inc.	2008-03	PHASE4
NCT00631449	COMPLETED	HIV Infections	University of California, San Francisco	2008-02	PHASE4
NCT00740064	UNKNOWN	HIV Infections	Denver Infectious Disease Consultants, PLLC	2008-05	PHASE4
NCT00554398	COMPLETED	HIV Infections	Germans Trias i Pujol Hospital	2007-11	PHASE3
NCT00443703	TERMINATED	HIV Infection	Merck Sharp & Dohme LLC	2007-05	PHASE3
NCT00685191	COMPLETED	HIV Infections	Germans Trias i Pujol Hospital	2008-06	PHASE4
NCT00802074	COMPLETED	Healthy	Garden State Infectious Disease Associates, PA	2008-12
NCT00618371	COMPLETED	HIV Infection	University of Pittsburgh	2007-10
NCT01000818	COMPLETED	HIV-1 Infection; HIV Infections	Merck Sharp & Dohme LLC	2008-06	PHASE1
NCT00523237	COMPLETED	HIV Infections	Stanford University	2007-10
NCT00520897	COMPLETED	HIV Infections	Canadian Immunodeficiency Research Collaborative	2007-04	PHASE2
NCT00660972	COMPLETED	HIV Infections	National Institute of Allergy and Infectious Diseases (NIAID)	2008-05	PHASE1
NCT00718536	COMPLETED	HIV Infections	Germans Trias i Pujol Hospital	2008-08	PHASE4
NCT00746499	COMPLETED	Pharmacokinetics	University of North Carolina, Chapel Hill	2008-09	PHASE1
NCT00784420	COMPLETED	Healthy Volunteers	Pfizer	2008-09	PHASE1
NCT00765271	COMPLETED	HIV	St Stephens Aids Trust	2008-05	PHASE1
NCT00443729	TERMINATED	HIV Infection	Merck Sharp & Dohme LLC	2007-05	PHASE3
NCT00618241	COMPLETED	HIV Infection	Radboud University Medical Center	2008-02	PHASE1
NCT00488059	TERMINATED	HIV Infections	Hoffmann-La Roche	2007-06	PHASE4
NCT00665717	COMPLETED	HIV Infections	Radboud University Medical Center	2008-05	PHASE1
NCT00614458	TERMINATED	HIV Infections	University of North Carolina, Chapel Hill	2007-04	PHASE2
NCT00515827	COMPLETED	HIV Infections	National Institute of Allergy and Infectious Diseases (NIAID)	2007-11	PHASE2
NCT00454337	COMPLETED	HIV Infections	French National Agency for Research on AIDS and Viral Hepatitis	2007-05	PHASE3
NCT00531999	COMPLETED	HIV Infections	St Stephens Aids Trust	2007-10	PHASE1
NCT00772551	COMPLETED	HIV	St Stephens Aids Trust	2008-06	PHASE1
NCT00529243	COMPLETED	HIV Infections	Kaiser Permanente	2007-09	PHASE3
NCT00614991	COMPLETED	Healthy	Garden State Infectious Disease Associates, PA	2008-01
NCT00666705	COMPLETED	Healthy	ViiV Healthcare	2008-02	PHASE4
NCT00460382	COMPLETED	HIV Infections	French National Agency for Research on AIDS and Viral Hepatitis	2007-05	PHASE2
NCT00564772	COMPLETED	Healthy	Allina Health System	2007-11	PHASE4
NCT00518297	COMPLETED	HIV Infections	Bristol-Myers Squibb	2007-08	PHASE1
NCT00293254	COMPLETED	HIV Infections	Merck Sharp & Dohme LLC	2006-02	PHASE3
NCT00293267	COMPLETED	HIV Infections	Merck Sharp & Dohme LLC	2006-02	PHASE3
NCT01253551	COMPLETED	Hepatitis C	Tibotec BVBA	2010-12	PHASE1
NCT01288755	COMPLETED	HIV Infections	Tibotec Pharmaceuticals, Ireland	2011-02	PHASE1
NCT01013987	UNKNOWN	HIV-1 Adults Patients; AIDS; Triple Class Failure	Fundación Huésped	2010-02	PHASE4

(data from https://clinicaltrials.gov, updated on 2026-08-19)

Check the Raltegravir potassium product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Compliance for Clinical Use

Mechanism and Biochemical Profile

Raltegravir potassium functions by selectively binding to the active site of human immunodeficiency virus type 1 (HIV-1) integrase, thereby inhibiting the essential strand transfer step required for insertion of the viral DNA into the host chromosome. By blocking viral genome integration, the compound halts viral replication and prevents the propagation of infection, providing the mechanistic foundation for its clinical utility in the treatment of HIV infections.

Appendix RUO and cGMP Quality Standards

Quality Dimension	RUO (Research Use Only)	cGMP (Current Good Manufacturing Practice)
Clinical Applicability	Prohibited in human clinical trials or medical diagnostics.	Mandatory for human clinical trials (Phase I–III) and therapies.
Regulatory Status	Non-regulated grade; exempt from drug manufacturing laws.	Legally enforced by health authorities (e.g., FDA, EMA, NMPA).
Facility Environment	Unclassified analytical or research laboratories.	Validated Cleanrooms (ISO Class 5–8) with continuous monitoring.
Quality Control	Basic purity and activity testing.	Rigorous safety release testing (Sterility, Endotoxin, Mycoplasma).
Process Validation	Basic equipment calibration; no process validation required.	Full qualification (IQ/OQ/PQ) and complete batch records.
Quality Assurance	Vendor self-declared without required formal QMS.	Mandatory QA/QC unit, Change Control, CAPA, and vendor audits.
Regulatory Impact	High risk of IND rejection if used as a critical raw material.	Required for IND/NDA filings, supported by Drug Master Files (DMF).

Footnotes

Regulatory Note: Governed by FDA (21 CFR Parts 210/211/312), EMA (EudraLex Vol 4), ICH Guidelines (E6/Q7/Q9/Q10), and compendial standards (USP <71>/<85>/<1043>).